Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/highly-specific-gene-silencing-by-artificial-micrornas-in-the-oxJeqaX80Z
References (57)
-
Qinglin Niu, Shih-Shun Lin, J. Reyes, Kuan-Chun Chen, Hui-Wen Wu, S. Yeh, N. Chua (2006)
Expression of artificial microRNAs in transgenic Arabidopsis thaliana confers virus resistanceNature Biotechnology, 24
-
R. Schwab, S. Ossowski, Markus Riester, N. Warthmann, D. Weigel (2006)
Highly Specific Gene Silencing by Artificial MicroRNAs in Arabidopsis[W][OA]The Plant Cell Online, 18
-
R. Schwab, J.F. Palatnik, M. Riester, C. Schommer, M. Schmid, D. Weigel (2005)
Specific Effects of MicroRNAs on the Plant TranscriptomeThe Plant Cell, 8
-
A. Khvorova, A. Reynolds, S. Jayasena (2003)
Functional siRNAs and miRNAs Exhibit Strand BiasCell, 115
-
J. Alonso, J. Ecker (2006)
Moving forward in reverse: genetic technologies to enable genome-wide phenomic screens in ArabidopsisNature Reviews Genetics, 7
-
M. Schroda, O. Vallon, J.P. Whitelegge, C.F. Beck, F.‐A. Wollman (2001)
The chloroplastic GrpE homolog of Chlamydomonas: two isoforms generated by differnetial splicingDevelopmental Cell, 13
-
I. Sizova, M. Fuhrmann, P. Hegemann (2001)
A Streptomyces rimosus aphVIII gene coding for a new type phosphotransferase provides stable antibiotic resistance to Chlamydomonas reinhardtii.Gene, 277 1-2
-
R. Schwab, J. Palatnik, Markus Riester, C. Schommer, M. Schmid, D. Weigel (2005)
Specific effects of microRNAs on the plant transcriptome.Developmental cell, 8 4
-
(2004)
White mutants of Chlamydomonas reinhardtii are defective in phytoene synthase -
J. Brennecke, A. Stark, R. Russell, S. Cohen (2005)
Principles of MicroRNA–Target RecognitionPLoS Biology, 3
-
M. Schroda, Dagmar Blöcker, C. Beck (2000)
The HSP70A promoter as a tool for the improved expression of transgenes in Chlamydomonas.The Plant journal : for cell and molecular biology, 21 2
-
M. Schroda, O. Vallon, J. Whitelegge, C. Beck, F. Wollman (2001)
The chloroplastic GrpE homolog of Chlamydomonas: two isoforms generated by differential splicing.The Plant cell, 13 12
-
M. Schroda (2006)
RNA silencing in Chlamydomonas: mechanisms and toolsCurrent Genetics, 49
-
Stefan Ameres, Javier Martinez, R. Schroeder (2007)
Molecular Basis for Target RNA Recognition and Cleavage by Human RISCCell, 130
-
Lee Lim, N. Lau, P. Garrett-engele, Andrew Grimson, Janell Schelter, J. Castle, D. Bartel, P. Linsley, Jason Johnson (2005)
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAsNature, 433
-
David Baulcombe (2006)
Short silencing RNA: the dark matter of genetics?Cold Spring Harbor symposia on quantitative biology, 71
-
N. Warthmann, Hao Chen, S. Ossowski, D. Weigel, P. Hervé (2008)
Highly Specific Gene Silencing by Artificial miRNAs in RicePLoS ONE, 3
-
P. Cardol, D. González-Halphen, A. Reyes-Prieto, D. Baurain, R. Matagne, C. Remacle (2005)
The Mitochondrial Oxidative Phosphorylation Proteome of Chlamydomonas reinhardtii Deduced from the Genome Sequencing Project1Plant Physiology, 137
-
M. Fuhrmann, Alke Stahlberg, E. Govorunova, Simone Rank, P. Hegemann (2001)
The abundant retinal protein of the Chlamydomonas eye is not the photoreceptor for phototaxis and photophobic responses.Journal of cell science, 114 Pt 21
-
P. Xu, Yuanji Zhang, L. Kang, M. Roossinck, K. Mysore (2006)
Computational Estimation and Experimental Verification of Off-Target Silencing during Posttranscriptional Gene Silencing in Plants1[W][OA]Plant Physiology, 142
-
K. Farh, Andrew Grimson, Calvin Jan, B. Lewis, W. Johnston, Lee Lim, C. Burge, D. Bartel (2005)
The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and EvolutionScience, 310
-
V. Ambros (2001)
microRNAs Tiny Regulators with Great PotentialCell, 107
-
Yan Zeng, E. Wagner, B. Cullen (2002)
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells.Molecular cell, 9 6
-
D. Schwarz, G. Hutvagner, T. Du, Zuoshang Xu, N. Aronin, P. Zamore (2003)
Asymmetry in the Assembly of the RNAi Enzyme ComplexCell, 115
-
Sayda Elbashir, Winfried Lendeckel, T. Tuschl (2001)
RNA interference is mediated by 21- and 22-nucleotide RNAs.Genes & development, 15 2
-
M. Kertesz, N. Iovino, U. Unnerstall, U. Gaul, E. Segal (2007)
The role of site accessibility in microRNA target recognitionCell, 39
-
E. Harris (1989)
The Chlamydomonas Sourcebook: A Comprehensive Guide to Biology and Laboratory Use -
V. Lumbreras, D. Stevens, S. Purton (1998)
Efficient foreign gene expression in Chlamydomonas reinhardtii mediated by an endogenous intronPlant Journal, 14
-
S. Ossowski, R. Schwab, D. Weigel (2008)
Gene silencing in plants using artificial microRNAs and other small RNAs.The Plant journal : for cell and molecular biology, 53 4
-
A. Molnár, F. Schwach, D. Studholme, E. Thuenemann, D. Baulcombe (2007)
miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtiiNature, 447
-
P. Xu, Y. Zhang, L. Kang, M.J. Roossinck, K.S. Mysore (2006)
Computational estimation and experimental verification of off‐target silencing during posttranscriptional gene silencing in plantsMolecular Cell, 142
-
J. Casas-Mollano, J. Rohr, Eun Kim, Eniko Balassa, Karin Dijk, Karin Dijk, H. Cerutti (2008)
Diversification of the Core RNA Interference Machinery in Chlamydomonas reinhardtii and the Role of DCL1 in Transposon SilencingGenetics, 179
-
Diana Dugas, B. Bartel (2008)
Sucrose induction of Arabidopsis miR398 represses two Cu/Zn superoxide dismutasesPlant Molecular Biology, 67
-
Shijun Mi, Tao Cai, Yugang Hu, Yemiao Chen, E. Hodges, Fangrui Ni, Liang Wu, Shan Li, Huanyu Zhou, Chengzu Long, She Chen, G. Hannon, Y. Qi (2008)
Sorting of Small RNAs into Arabidopsis Argonaute Complexes Is Directed by the 5′ Terminal NucleotideCell, 133
-
B. Lewis, C. Burge, D. Bartel (2005)
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA TargetsCell, 120
-
D. Bartel (2004)
MicroRNAs Genomics, Biogenesis, Mechanism, and FunctionCell, 116
-
S. Merchant, S. Prochnik, O. Vallon, E. Harris, Steven Karpowicz, G. Witman, A. Terry, A. Salamov, Lillian Fritz-Laylin, L. Marechal-Drouard, W. Marshall, L. Qu, D. Nelson, A. Sanderfoot, M. Spalding, V. Kapitonov, Q. Ren, P. Ferris, E. Lindquist, H. Shapiro, S. Lucas, J. Grimwood, J. Schmutz, P. Cardol, H. Cerutti, G. Chanfreau, Chun-long Chen, V. Cognat, M. Croft, Rachel Dent, S. Dutcher, E. Fernández, H. Fukuzawa, David González-Ballester, D. González-Halphen, A. Hallmann, M. Hanikenne, M. Hippler, W. Inwood, K. Jabbari, M. Kalanon, R. Kuras, P. Lefebvre, S. Lemaire, A. Lobanov, M. Lohr, A. Manuell, I. Meier, L. Mets, M. Mittag, T. Mittelmeier, J. Moroney, J. Moseley, C. Napoli, A. Nedelcu, K. Niyogi, S. Novoselov, I. Paulsen, G. Pazour, S. Purton, J. Ral, D. Riaño-Pachón, W. Riekhof, Linda Rymarquis, M. Schroda, D. Stern, J. Umen, R. Willows, N. Wilson, Sara Zimmer, J. Allmer, J. Balk, K. Bišová, Chong Chen, M. Eliáš, K. Gendler, C. Hauser, M. Lamb, H. Ledford, J. Long, J. Minagawa, M. Page, Junmin Pan, W. Pootakham, S. Roje, A. Rose, E. Stahlberg, A. Terauchi, Pinfen Yang, S. Ball, C. Bowler, C. Dieckmann, V. Gladyshev, P. Green, R. Jorgensen, S. Mayfield, B. Mueller‐Roeber, S. Rajamani, R. Sayre, P. Brokstein, I. Dubchak, D. Goodstein, Leila Hornick, Y. Huang, Jinal Jhaveri, Yi Luo, Diego Martínez, W. Ngau, Bobby Otillar, Alexander Poliakov, Aaron Porter, L. Szajkowski, Gregory Werner, Kemin Zhou, I. Grigoriev, D. Rokhsar, A. Grossman (2007)
The Chlamydomonas Genome Reveals the Evolution of Key Animal and Plant FunctionsScience, 318
-
J. Alvarez, I. Pekker, A. Goldshmidt, Eyal Blum, Z. Amsellem, Y. Eshed (2006)
Endogenous and Synthetic MicroRNAs Stimulate Simultaneous, Efficient, and Localized Regulation of Multiple Targets in Diverse Species[W]The Plant Cell Online, 18
-
Madhuri Gandikota, R. Birkenbihl, S. Höhmann, G. Cardon, H. Saedler, P. Huijser (2007)
The miRNA156/157 recognition element in the 3' UTR of the Arabidopsis SBP box gene SPL3 prevents early flowering by translational inhibition in seedlings.The Plant journal : for cell and molecular biology, 49 4
-
N. Fischer, J. Rochaix (2001)
The flanking regions of PsaD drive efficient gene expression in the nucleus of the green alga Chlamydomonas reinhardtiiMolecular Genetics and Genomics, 265
-
T. Zhao, Guanglin Li, Shijun Mi, Shan Li, G. Hannon, Xiu-Jie Wang, Y. Qi (2007)
A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii.Genes & development, 21 10
-
Y. Zeng, E.J. Wagner, B.R. Cullen (2002)
Both natural and designed micro RNAs technique can inhibit the expression of cognate mRNAs when expressed in human cellsGenes Dev., 9
-
Ziqiang Li, C. Woo, M. Iglesias-Ussel, Diana Ronai, M. Scharff (2004)
The generation of antibody diversity through somatic hypermutation and class switch recombination.Genes & development, 18 1
-
M. Schroda (2006)
RNA silencing in Chlamydomonas: mechanisms and toolsPlant J., 49
-
P. Brodersen, Lali Sakvarelidze-Achard, M. Bruun-Rasmussen, P. Dunoyer, Yoshiharu Yamamoto, L. Sieburth, O. Voinnet (2008)
Widespread Translational Inhibition by Plant miRNAs and siRNAsScience, 320
-
Q.W. Niu, S.S. Lin, J.L. Reyes, K.C. Chen, H.W. Wu, S.D. Yeh, N.H. Chua (2006)
Expression of artificial microRNAs in transgenic Arabidopsis thaliana confers virus resistancePlant J., 24
-
E. Parizotto, P. Dunoyer, Nadia Rahm, C. Himber, O. Voinnet (2004)
In vivo investigation of the transcription, processing, endonucleolytic activity, and functional relevance of the spatial distribution of a plant miRNA.Genes & development, 18 18
-
C. Llave, Zhixin Xie, K. Kasschau, J. Carrington (2002)
Cleavage of Scarecrow-like mRNA Targets Directed by a Class of Arabidopsis miRNAScience, 297
-
Xuemei Chen (2004)
A MicroRNA as a Translational Repressor of APETALA2 in Arabidopsis Flower DevelopmentScience, 303
-
S. Ossowski, R. Schwab, D. Weigel (2008)
Gene silencing in plants using artificial microRNAs and other small RNAsGenes Dev., 53
-
M. Aukerman, H. Sakai (2003)
Regulation of Flowering Time and Floral Organ Identity by a MicroRNA and Its APETALA2-Like Target Genes Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.016238.The Plant Cell Online, 15
-
J. Rohr, Nandita Sarkar, Susan Balenger, Byeong-ryool Jeong, H. Cerutti (2004)
Tandem inverted repeat system for selection of effective transgenic RNAi strains in Chlamydomonas.The Plant journal : for cell and molecular biology, 40 4
-
E.A. Parizotto, P. Dunoyer, N. Rahm, C. Himber, O. Voinnet (2004)
In vivo investigation of the transcription, processing, endonucleolytic activity, and functional relevance of the spatial distribution of a plant miRNAThe Plant Journal, 18
-
Ulrike Mückstein, Hakim Tafer, J. Hackermüller, S. Bernhart, P. Stadler, I. Hofacker (2006)
Thermodynamics of RNA-RNA BindingBioinformatics, 22 10
-
K. Kindle (1990)
High-frequency nuclear transformation of Chlamydomonas reinhardtii.Proceedings of the National Academy of Sciences of the United States of America, 87
-
J. Rohr, N. Sarkar, S. Balenger, B.‐R. Jeong, H. Cerutti (2004)
Tandem inverted repeat system for selection of effective transgenic RNAi strains in ChlamydomonasCurr. Genet., 40
-
N. Warthmann, H. Chen, S. Ossowski, D. Weigel, P. Herve (2008)
Highly specific gene silencing by artificial miRNAs in ricePlant Physiol., 3
- Publisher
- Wiley
- Copyright
- Copyright © 2009 Wiley Subscription Services, Inc., A Wiley Company
- ISSN
- 0960-7412
- eISSN
- 1365-313X
- DOI
- 10.1111/j.1365-313X.2008.03767.x
- pmid
- 19054357
- Publisher site
- See Article on Publisher Site
Abstract
MicroRNAs (miRNAs) are small RNAs, 21 to 22 nucleotides long, with important regulatory roles. They are processed from longer RNA molecules with imperfectly matched foldback regions and they function in modulating the stability and translation of mRNA. Recently, we and others have demonstrated that the unicellular alga Chlamydomonas reinhardtii, like diverse multicellular organisms, contains miRNAs. These RNAs resemble the miRNAs of land plants in that they direct site‐specific cleavage of target mRNA with miRNA‐complementary motifs and, presumably, act as regulatory molecules in growth and development. Utilizing these findings we have developed a novel artificial miRNA system based on ligation of DNA oligonucleotides that can be used for specific high‐throughput gene silencing in green algae.
Journal
The Plant Journal – Wiley
Published: Apr 1, 2009
Keywords: ; ; ; ;