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(2007)
Pediatr Nephrol -
Raymond Harris, E. Neilson (2006)
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- Publisher
- Springer Journals
- Copyright
- Copyright © 2007 by IPNA
- Subject
- Medicine & Public Health; Pediatrics
- ISSN
- 0931-041X
- eISSN
- 1432-198X
- DOI
- 10.1007/s00467-006-0357-2
- pmid
- 17216262
- Publisher site
- See Article on Publisher Site
Abstract
Focal segmental glomerulosclerosis (FSGS) is a major cause of idiopathic steroid-resistant nephrotic syndrome (SRNS) and end-stage kidney disease (ESKD). In recent years, animal models and studies of familial forms of nephrotic syndrome helped elucidate some mechanisms of podocyte injury and disease progression in FSGS. This article reviews some of the experimental and clinical data on the pathophysiology of FSGS.
Journal
Pediatric Nephrology – Springer Journals
Published: Jan 10, 2007