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Diabetologia (2015) 58:199–200 DOI 10.1007/s00125-014-3425-3 LETTER Paolo Palatini Received: 17 September 2014 /Accepted: 3 October 2014 /Published online: 26 October 2014 Springer-Verlag Berlin Heidelberg 2014 . . . . Keywords Caffeine Coffee CYP1A2 Genetics Type 2 Coffee is a ‘blend’ of a large number of bioactive diabetes chemicals that may have different effects on glycaemic control. Among these, the polyphenols dihydrocaffeic acid and chlorogenic acid seem to act as protective antioxidants To the Editor: Controversy still exists over the relationship and to have beneficial actions on glucose homeostasis [4]. In a between coffee consumption and risk of type 2 diabetes previous analysis of the Health Professionals Follow-Up mellitus. A number of prospective studies have reported a Study, the same group of investigators found that consump- negative association between increased coffee consumption tion of caffeinated coffee was associated with a 4% lower risk and risk of type 2 diabetes [1]. According to a recent meta- of type 2 diabetes (RR 0.96; 95% CI 0.93, 0.98), and that analysis, the incidence of type 2 diabetes decreased by 12% decaffeinated coffee was associated with a 7% lower risk of for every two cups per day increase in caffeinated coffee type 2 diabetes
Diabetologia – Springer Journals
Published: Jan 1, 2015
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