Access the full text.
Sign up today, get DeepDyve free for 14 days.
B. Huettel, T. Kanno, L. Daxinger, W. Aufsatz, A. Matzke, M. Matzke (2006)
Endogenous targets of RNA‐directed DNA methylation and Pol IV in ArabidopsisThe EMBO Journal, 25
A. Verdel, Aurélia Vavasseur, Madalen Gorrec, Leila Touat‐Todeschini (2009)
Common themes in siRNA-mediated epigenetic silencing pathways.The International journal of developmental biology, 53 2-3
C. Pikaard, J. Haag, T. Ream, A. Wierzbicki (2008)
Roles of RNA polymerase IV in gene silencing.Trends in plant science, 13 7
Xin‐Jian He, Yi-Feng Hsu, Shihua Zhu, A. Wierzbicki, O. Pontes, C. Pikaard, Hai-liang Liu, Co-Shine Wang, Hailing Jin, Jian‐Kang Zhu (2009)
An Effector of RNA-Directed DNA Methylation in Arabidopsis Is an ARGONAUTE 4- and RNA-Binding ProteinCell, 137
S. Lahmy, D. Pontier, Emilie Cavel, Danielle Vega, Mahmoud El-Shami, T. Kanno, T. Lagrange (2009)
PolV(PolIVb) function in RNA-directed DNA methylation requires the conserved active site and an additional plant-specific subunitProceedings of the National Academy of Sciences, 106
Xin‐Jian He, Yi-Feng Hsu, O. Pontes, Jianhua Zhu, Jian Lu, R. Bressan, C. Pikaard, Co-Shine Wang, Jian‐Kang Zhu (2009)
NRPD4, a protein related to the RPB4 subunit of RNA polymerase II, is a component of RNA polymerases IV and V and is required for RNA-directed DNA methylation.Genes & development, 23 3
Assen Roguev, Sourav Bandyopadhyay, M. Zofall, Ke Zhang, Tamás Fischer, Sean Collins, Hongjing Qu, M. Shales, Han-Oh Park, J. Hayles, K. Hoe, Dong-Uk Kim, T. Ideker, S. Grewal, J. Weissman, N. Krogan (2008)
Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission YeastScience, 322
Linfeng Huang, Alexandra Jones, I. Searle, K. Patel, Hannes Vogler, N. Hubner, D. Baulcombe (2009)
An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase IINature Structural &Molecular Biology, 16
M. Matzke, T. Kanno, L. Daxinger, B. Huettel, A. Matzke (2009)
RNA-mediated chromatin-based silencing in plants.Current opinion in cell biology, 21 3
Mustapha Aouida, N. Pagé, A. Leduc, M. Peter, D. Ramotar (2004)
A Genome-Wide Screen in Saccharomyces cerevisiae Reveals Altered Transport As a Mechanism of Resistance to the Anticancer Drug BleomycinCancer Research, 64
L. Daxinger, T. Kanno, E. Bucher, J. Winden, Ulf Naumann, A. Matzke, M. Matzke (2009)
A stepwise pathway for biogenesis of 24‐nt secondary siRNAs and spreading of DNA methylationThe EMBO Journal, 28
M Matzke, T Kanno, L Daxinger, B Huettel, AJM Matzke (2009)
RNA‐mediated chromatin‐based silencing in plants. Targets of RNA‐directed DNA methylationCurr Opin Cell Biol, 21
L. Peiró-Chova, F. Estruch (2009)
The Yeast RNA Polymerase II-associated Factor Iwr1p Is Involved in the Basal and Regulated Transcription of Specific Genes*The Journal of Biological Chemistry, 284
Zhenghe Li, D. Barajas, T. Panavas, D. Herbst, P. Nagy (2008)
Cdc34p Ubiquitin-Conjugating Enzyme Is a Component of the Tombusvirus Replicase Complex and Ubiquitinates p33 Replication ProteinJournal of Virology, 82
A. Wierzbicki, J. Haag, C. Pikaard (2008)
Noncoding Transcription by RNA Polymerase Pol IVb/Pol V Mediates Transcriptional Silencing of Overlapping and Adjacent GenesCell, 135
M. Matzke, T. Kanno, B. Huettel, L. Daxinger, A. Matzke (2007)
Targets of RNA-directed DNA methylation.Current opinion in plant biology, 10 5
RdDM and development require an IWR1-type factor T
Natacha Bies-Ethève, D. Pontier, S. Lahmy, Claire Picart, Danielle Vega, R. Cooke, T. Lagrange (2009)
RNA‐directed DNA methylation requires an AGO4‐interacting member of the SPT5 elongation factor familyEMBO reports, 10
A. Konieczny, F. Ausubel (1993)
A procedure for mapping Arabidopsis mutations using co-dominant ecotype-specific PCR-based markers.The Plant journal : for cell and molecular biology, 4 2
N. Krogan, G. Cagney, Haiyuan Yu, Gouqing Zhong, Xinghua Guo, A. Ignatchenko, Joyce Li, S. Pu, Nira Datta, A. Tikuisis, Thanuja Punna, J. Peregrín-Alvarez, M. Shales, Xin Zhang, Michael Davey, M. Robinson, Alberto Paccanaro, J. Bray, Anthony Sheung, B. Beattie, D. Richards, Veronica Canadien, A. Lalev, Frank Mena, Peter Wong, A. Starostine, Myra Canete, James Vlasblom, Samuel Wu, Chris Orsi, Sean Collins, Shamanta Chandran, R. Haw, J. Rilstone, Kiran Gandi, Natalie Thompson, Gabriel Musso, P. Onge, S. Ghanny, M. Lam, G. Butland, Amin Altaf-Ul, S. Kanaya, A. Shilatifard, E. O’Shea, J. Weissman, C. Ingles, T. Hughes, J. Parkinson, M. Gerstein, S. Wodak, A. Emili, J. Greenblatt (2006)
Global landscape of protein complexes in the yeast Saccharomyces cerevisiaeNature, 440
T. Ream, J. Haag, A. Wierzbicki, C. Nicora, A. Norbeck, Jian‐Kang Zhu, G. Hagen, T. Guilfoyle, L. Paša-Tolić, C. Pikaard (2009)
Subunit compositions of the RNA-silencing enzymes Pol IV and Pol V reveal their origins as specialized forms of RNA polymerase II.Molecular cell, 33 2
Sean Collins, K. Miller, Nancy Maas, Assen Roguev, Jeffrey Fillingham, Clement Chu, M. Schuldiner, M. Gebbia, J. Recht, M. Shales, Huiming Ding, Hong Xu, Junhong Han, K. Ingvarsdóttir, Benjamin Cheng, B. Andrews, Charles Boone, S. Berger, P. Hieter, Zhiguo Zhang, Grant Brown, C. Ingles, A. Emili, C. Allis, D. Toczyski, J. Weissman, J. Greenblatt, N. Krogan (2007)
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction mapNature, 446
T. Kanno, B. Huettel, M. Mette, W. Aufsatz, Estelle Jaligot, L. Daxinger, David Kreil, M. Matzke, A. Matzke (2005)
Atypical RNA polymerase subunits required for RNA-directed DNA methylationNature Genetics, 37
T. Kanno, E. Bucher, L. Daxinger, B. Huettel, Gudrun Böhmdorfer, W. Gregor, David Kreil, M. Matzke, A. Matzke (2008)
A structural-maintenance-of-chromosomes hinge domain–containing protein is required for RNA-directed DNA methylationNature Genetics, 40
N. Pagé, Manon Gérard-Vincent, Patrice Ménard, M. Beaulieu, M. Azuma, G. Dijkgraaf, Huijuan Li, José Marcoux, Thuy Nguyen, Tim Dowse, A. Sdicu, H. Bussey (2003)
A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin.Genetics, 163 3
RNA‐directed DNA methylation (RdDM) in plants requires two RNA polymerase (Pol) II‐related RNA polymerases, namely Pol IV and Pol V. A genetic screen designed to reveal factors that are important for RdDM in a developmental context in Arabidopsis identified DEFECTIVE IN MERISTEM SILENCING 4 (DMS4). Unlike other mutants defective in RdDM, dms4 mutants have a pleiotropic developmental phenotype. The DMS4 protein is similar to yeast IWR1 (interacts with RNA polymerase II), a conserved putative transcription factor that interacts with Pol II subunits. The DMS4 complementary DNA partly complements the K1 killer toxin hypersensitivity of a yeast iwr1 mutant, suggesting some functional conservation. In the transgenic system studied, mutations in DMS4 directly or indirectly affect Pol IV‐dependent secondary short interfering RNAs, Pol V‐mediated RdDM, Pol V‐dependent synthesis of intergenic non‐coding RNA and expression of many Pol II‐driven genes. These data suggest that DMS4 might be a regulatory factor for several RNA polymerases, thus explaining its diverse roles in the plant.
EMBO Reports – Wiley
Published: Jan 1, 2010
Keywords: ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.