Access the full text.
Sign up today, get DeepDyve free for 14 days.
Martin Swerdlow (1969)
LIVER BIOPSY INTERPRETATIONThe Ulster Medical Journal, 38
(1984)
Ischaemic hepatitis : Clinical features , diagnosis and prognosis . A u s ~ N . Z
E. Schmidt, F. Schmidt (1970)
Enzyme activities in human liver.Enzymologia biologica et clinica, 11 1
(1984)
Ischaemic hepatitis: Clinical features, diagnosis and prognosis. A u s~ N
(1979)
T h e nature of piecemeal necrosis in chronic active hepatitis
(1970)
Studies of enzyme elimination. I. T h e half lives of some enzymes in man
(1980)
, er al . T h e nature of piecemeal necrosis in chronic active hepatitis
P. Gibson, F. Dudley (1984)
Ischemic hepatitis: clinical features, diagnosis and prognosis.Australian and New Zealand journal of medicine, 14 6
J. Kerr, J. Searle, W. Halliday, I. Roberts, W. Cooksley, J. Halliday, L. Holder, W. Burnett, L. Powell (1979)
THE NATURE OF PIECEMEAL NECROSIS IN CHRONIC ACTIVE HEPATITISThe Lancet, 314
M. West, Hyman Zimmerman (1959)
Serum enzymes in hepatic disease.The Medical clinics of North America, 43 2
To examine the hypothesis that different histological forms of liver cell death result in a characteristic serum enzyme pattern, the serum concentration of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and lactic dehydrogenase (LD) enzymes were measured in three aetiologically distinct groups of patients with acute hepatocellular injury. Thirty patients had serologically confirmed acute viral hepatitis B, twenty had histologically proven ischaemic hepatitis and five had paracetamol hepatotoxicity. Serum AST and ALT levels were similar in the patients with viral and ischaemic hepatitis, but the serum LD was significantly higher (P < 0.001) in the ischaemic hepatitis group. The pattern of enzyme elevation in the patients with paracetamol hepatotoxicity was similar to that found in ischaemic hepatitis. AST/LD and ALT/LD ratios, which were greater than 2 and 3 respectively, usually distinguished the patients with viral hepatitis from those with ischaemic hepatitis or paracetamol hepatotoxicity. Because of differences in the clearance of these enzymes from the serum it is likely that the AST/LD ratio will prove of greater discriminatory value and that this will be most evident early in the patient's clinical course and become progressively less with time.
Journal of Gastroenterology and Hepatology – Wiley
Published: Oct 1, 1987
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.