Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Kraak, P. Wijnands, H. Govers, W. Admiraal, P. Voogt (1997)
Structural‐based differences in ecotoxicity of benzoquinoline isomers to the zebra mussel (Dreissena polymorpha)Environmental Toxicology and Chemistry, 16
D. Licht, S. Johansen, E. Arvin, B. Ahring (1997)
Transformation of indole and quinoline by Desulfobacterium indolicum (DSM 3383)Applied Microbiology and Biotechnology, 47
P. Vlaardingen, W. Steinhoff, W. Admiraal, P. Voogt (1996)
PROPERTY-TOXICITY RELATIONSHIPS OF AZAARENES TO THE GREEN ALGA SCENEDESMUS ACUMINATUSEnvironmental Toxicology and Chemistry, 15
(2007)
Effectdirected analysis of key toxicants in Europe in river basins—A review
(2006)
Freshwater alga and cyanobacteria growth inhibition test. Guideline 201
(1986)
Grundriss der biologischen Statistik
J. Bundy, J. Bundy, A. Morriss, D. Durham, C. Campbell, G. Paton (2001)
Development of QSARs to investigate the bacterial toxicity and biotransformation potential of aromatic heterocylic compounds.Chemosphere, 42 8
A. Eisentraeger, C. Brinkmann, K. Michel, S. Hahn, M. Huettner, G. Weber (2004)
Development of automated high-throughput ecotoxicity and genotoxicity test systems and fields of application.Water science and technology : a journal of the International Association on Water Pollution Research, 50 5
(2007)
Bioassaydirected identification of toxic-organic compounds in creosotecontaminated groundwater
(2005)
Water quality-Determination of the genotoxicity of water and waste water-Salmonella/microsome test (Ames test). ISO 16240
(1996)
Water quality — Determination of the inhibition of the mobility of Daphnia magna Straus ( Cladocera , Crustaceae ) — Acute toxicity test
S. Droge, M. Paumen, E. Bleeker, M. Kraak, C. Gestel (2006)
Chronic toxicity of polycyclic aromatic compounds to the springtail Folsomia candida and the enchytraeid Enchytraeus crypticusEnvironmental Toxicology and Chemistry, 25
W. Brack, K. Schirmer (2003)
Effect-directed identification of oxygen and sulfur heterocycles as major polycyclic aromatic cytochrome P4501A-inducers in a contaminated sediment.Environmental science & technology, 37 14
E. Bleeker, S. Wiegman, P. Voogt, M. Kraak, H. Leslie, E. Haas, W. Admiraal (2002)
Toxicity of azaarenes.Reviews of environmental contamination and toxicology, 173
H. Sundberg, R. Ishaq, G. Akerman, U. Tjärnlund, Y. Zebühr, M. Linderoth, D. Broman, L. Balk (2005)
A bio-effect directed fractionation study for toxicological and chemical characterization of organic compounds in bottom sediment.Toxicological sciences : an official journal of the Society of Toxicology, 84 1
T. Nielsen, K. Siigur, C. Helweg, O. Jørgensen, P. Hansen, U. Kirso (1997)
Sorption of Polycyclic Aromatic Compounds to Humic Acid As Studied by High-Performance Liquid ChromatographyEnvironmental Science & Technology, 31
(2004)
Water quality-Fresh water algal growth inhibition test with unicellular green algae
D. Eastmond, G. Booth, Milton Lee (1984)
Toxicity, accumulation, and elimination of polycyclic aromatic sulfur heterocycles inDaphnia magnaArchives of Environmental Contamination and Toxicology, 13
David Seymour, A. Verbeek, S. Hrudey, P. Fedorak (1997)
Acute toxicity and aqueous solubility of some condensed thiophenes and their microbial metabolitesEnvironmental Toxicology and Chemistry, 16
Marie Feldmannová, K. Hilscherová, B. Maršálek, L. Bláha (2006)
Effects of N‐heterocyclic polyaromatic hydrocarbons on survival, reproduction, and biochemical parameters in Daphnia magnaEnvironmental Toxicology, 21
A. Reineke, T. Göen, A. Preiss, J. Hollender (2007)
Quinoline and derivatives at a tar oil contaminated site: hydroxylated products as indicator for natural attenuation?Environmental science & technology, 41 15
B. Parkhurst, A. Bradshaw, J. Forte, G. Wright (1981)
The chronic toxicity to Daphnia magna of acridine, a representative azaarene present in synthetic fossil fuel products and wastewatersEnvironmental Pollution Series A, Ecological and Biological, 24
J. Vondráček, K. Chramostová, M. Plíšková, L. Bláha, W. Brack, A. Kozubík, M. Machala (2004)
Induction of aryl hydrocarbon receptor–mediated and estrogen receptor–mediated activities, and modulation of cell proliferation by dinaphthofuransEnvironmental Toxicology and Chemistry, 23
D. Zamfirescu, P. Grathwohl (2001)
Occurrence and attenuation of specific organic compounds in the groundwater plume at a former gasworks site.Journal of contaminant hydrology, 53 3-4
Heterocyclic aromatic hydrocarbons containing nitrogen, sulfur, or oxygen (NSO‐HET), have been detected in air, soil, sewage sludge, marine environments, and freshwater sediments. Since toxicity data on this class of substances are scarce, the present study focuses on possible implications NSO‐HET have for ecotoxicity (algae and daphnids) and mutagenicity (Salmonella/microsome test). A combination of bioassays and chemical‐analytical quantification of the test compounds during toxicity assays should aid in determination of the hazard potential. Samples of the test concentrations of 14 NSO‐HET were taken at the beginning and end of the bioassays; these samples were then quantified by high‐performance liquid chromatography. The toxicity potential of the substances was evaluated and compared with the toxicity calculated with the nominal concentrations. Significantly different results were obtained primarily for volatile or highly hydrophobic NSO‐HET. The concentration of heterocyclic hydrocarbons can change significantly during the algae and Daphnia test. The EC50 values (effective concentration value: the concentration of a chemical that is required to produce a 50% effect) calculated with the nominal concentrations underestimate the toxicity by a factor of up to 50. Prioritizing the tested compounds according to toxicity, the mutagenic and toxic compounds quinoline, 6‐methylquinoline, and xanthene have to be listed first. The greatest ecotoxic potential on algae and daphnids was determined for dibenzothiophene followed by acridine. In the Daphnia magna immobilization test, benzofuran, dibenzofuran, 2‐methylbenzofuran, and 2,3‐dimethylbenzofuran and also carbazole are ecotoxicologically relevant with EC50 values below 10 mg/L. These substances are followed by indole with a high ecotoxic effect to daphnids and less effect to algae. Only minor toxic effects were observed for 2‐methylpyridine and 2,4,6‐trimethylpyridine.
Environmental Toxicology & Chemistry – Wiley
Published: Jul 1, 2008
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.