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Cryosurgery for Skin Cancer: 30‐Year Experience and Cure Rates

Cryosurgery for Skin Cancer: 30‐Year Experience and Cure Rates Background. Cryosurgery is capable of destroying nonmelanotic skin cancers, and numerous reports from around the world attest to its efficacy. However, there are few long‐term data of large series of patients that were treated in this manner. Objective. To report and evaluate the author's experience of using deep cryosurgery in the management of basal and squamous cell carcinomas on all areas of the body over a 30‐year period. Methods. Records of cryosurgical treatment in 4406 new and recurrent basal and squamous cell carcinomas in 2932 patients were reviewed. All cases were treated by the same physician. Liquid nitrogen was the cryogen. The open spray technique was mostly employed, and a double freeze–thaw cycle was carried out. Treatment was monitored clinically as well as by measurement of the tissue temperature in some cases;−50° to−60°C was reached in the tissue during the past 2 decades. Results. The overall 30‐year cure rate was 98.6% and was remarkably similar in all locations. A recent 5‐year cure rate of 522 cases was 99.0%. There were five recurrences. Conclusions. Cryosurgery is a safe and effective treatment for selected nonmelanotic skin cancers and yields a high cure rate. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Dermatologic Surgery Wolters Kluwer Health

Cryosurgery for Skin Cancer: 30‐Year Experience and Cure Rates

Dermatologic Surgery , Volume 30 – Feb 1, 2004

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References (26)

Publisher
Wolters Kluwer Health
Copyright
Copyright © 2004 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1076-0512
eISSN
1524-4725
DOI
10.1111/j.1524-4725.2004.30090.x
Publisher site
See Article on Publisher Site

Abstract

Background. Cryosurgery is capable of destroying nonmelanotic skin cancers, and numerous reports from around the world attest to its efficacy. However, there are few long‐term data of large series of patients that were treated in this manner. Objective. To report and evaluate the author's experience of using deep cryosurgery in the management of basal and squamous cell carcinomas on all areas of the body over a 30‐year period. Methods. Records of cryosurgical treatment in 4406 new and recurrent basal and squamous cell carcinomas in 2932 patients were reviewed. All cases were treated by the same physician. Liquid nitrogen was the cryogen. The open spray technique was mostly employed, and a double freeze–thaw cycle was carried out. Treatment was monitored clinically as well as by measurement of the tissue temperature in some cases;−50° to−60°C was reached in the tissue during the past 2 decades. Results. The overall 30‐year cure rate was 98.6% and was remarkably similar in all locations. A recent 5‐year cure rate of 522 cases was 99.0%. There were five recurrences. Conclusions. Cryosurgery is a safe and effective treatment for selected nonmelanotic skin cancers and yields a high cure rate.

Journal

Dermatologic SurgeryWolters Kluwer Health

Published: Feb 1, 2004

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