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Multitheragnostic Multi‐GNRs Crystal‐Seeded Magnetic Nanoseaurchin for Enhanced In Vivo Mesenchymal‐Stem‐Cell Homing, Multimodal Imaging, and Stroke Therapy

Multitheragnostic Multi‐GNRs Crystal‐Seeded Magnetic Nanoseaurchin for Enhanced In Vivo... A multifunctional nanoseaurchin probe in which mesoporous silica nanobeads with iron oxide nanoparticles embedded and multi‐gold nanorods crystal‐seeded are fabricated and labeled with umbilical cord mesenchymal stem cells through endocytosis. This nanoplatform enables efficient magnetic remote‐controlled guiding for stem cell homing, and provides dual modalities of photoacoustic imaging and magnetic resonance imaging for in situ tracking and long‐term monitoring to achieve therapeutic efficacy. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Advanced Materials Wiley

Multitheragnostic Multi‐GNRs Crystal‐Seeded Magnetic Nanoseaurchin for Enhanced In Vivo Mesenchymal‐Stem‐Cell Homing, Multimodal Imaging, and Stroke Therapy

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References (30)

Publisher
Wiley
Copyright
Copyright © 2015 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
ISSN
0935-9648
eISSN
1521-4095
DOI
10.1002/adma.201502784
pmid
26403165
Publisher site
See Article on Publisher Site

Abstract

A multifunctional nanoseaurchin probe in which mesoporous silica nanobeads with iron oxide nanoparticles embedded and multi‐gold nanorods crystal‐seeded are fabricated and labeled with umbilical cord mesenchymal stem cells through endocytosis. This nanoplatform enables efficient magnetic remote‐controlled guiding for stem cell homing, and provides dual modalities of photoacoustic imaging and magnetic resonance imaging for in situ tracking and long‐term monitoring to achieve therapeutic efficacy.

Journal

Advanced MaterialsWiley

Published: Nov 1, 2015

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