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B. Myhre, L. Walker, M. White (1974)
Bacteriocidal Properties of Platelet ConcentratesTransfusion, 14
W. Mallin, D. Reuss, J. Bracke, Susan Roberts, G. Moore (1973)
Bacteriological Study of Platelet Concentrates Stored at 22 C and 4 CTransfusion, 13
(1971)
Fine: A technique for quantitative measurement of endotoxin in human plasma
(1972)
Bacteriocidal properties of platelet concentrate. Presented at the XXV Annual Meeting of the American Association of Blood BanksXI11 International Congress
(1971)
An epidemic of septicemia due to Salmonella cholerae-suis var kunzendorf
A. Katz, R. Tilton (1970)
Sterility of Platelet Concentrates Stored at 25 CTransfusion, 10
T. Gibson, W. Norris (1958)
Skin fragments removed by injection needles.Lancet, 2 7054
(1972)
Fine , 1 . : Detection of contaminated blood
Section of Immunology and Cell Biology
(1971)
terial proliferation in platelet products stored at room temperature : transfusion - in - ducal enterobacter sepsis
A. Braude, J. Sanford, J. Bartlett, O. Mallery (1952)
Effects and clinical significance of bacterial contaminants in transfused blood.The Journal of laboratory and clinical medicine, 39 6
J. James (1959)
Bacterial Contamination of Preserved BloodVox Sanguinis, 4
M. Pittman (1953)
A study of bacteria implicated in transfusion reactions and of bacteria isolated from blood products.The Journal of laboratory and clinical medicine, 42 2
D. Buchholz, V. Young, N. Friedman, J. Reilly, M. Mardiney (1971)
Bacterial proliferation in platelet products stored at room temperature. Transfusion-induced Enterobacter sepsis.The New England journal of medicine, 285 8
J. Fine (1972)
Detection of contaminated blood.Lancet, 2 7784
H. Silver, A. Sonnenwirth, L. Beisser (1970)
Bactériologic Study of Platelet Concentrates Prepared and Stored without RefrigerationTransfusion, 10
R. Reinhold, J. Fine (1971)
A Technique for Quantitative Measurement of Endotoxin in Human Plasma 1Proceedings of the Society for Experimental Biology and Medicine, 137
(1972)
Bacteriological study of platelet concentrates stored at 4 C or 22 C. Presented at the XXV Annual Meeting of the American Association of Blood Banks-XI11 International Congress
(1965)
The bacteriology of normal skin
A study of bacterial contamination in platelet products stored at ambient temperature demonstrated the presence of bacteria in 2.4 per cent of platelets as determined by culturing platelet pools. The recovery of bacteria increased as storage time prior to culture increased, which suggested bacterial proliferation during storage. While many of the bacteria recovered were normal skin flora, i.e., diphtheroids and Staphylococcus epidermidis, pathogens such as Enterobacter cloacae, Staphylococcus aureus, and Pseudomonas spp. were recovered several times. Quantitative cultures were performed in the present study which demonstrated that most pools contained relatively few microorganisms, although some harbored more than 500 bacteria/ml after ambient temperature storage. The introduction of microorganisms during the pooling procedure can not be ruled out. Of 3,251 units not subjected to pooling, 45 (1.4%) were found to contain bacteria. Platelets kept at ambient temperature for 11 to 71 days were cultured and 38 of 631 (6.0%) individual units contained bacteria. Four additional severe patient reactions and two deaths have occurred consequent to transfusion of platelets contaminated with bacteria. These observations lead to the conclusion that caution should be exercised in the use of platelets stored at ambient temperature.
Transfusion – Wiley
Published: Sep 10, 1973
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