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M. Ahel, T. Conrad, W. Giger (1987)
Persistent organic chemicals in sewage effluents. 3. Determinations of nonylphenoxy carboxylic acids by high-resolution gas chromatography/mass spectrometry and high-performance liquid chromatography.Environmental science & technology, 21 7
T. Colborn, C. Clement (1992)
Chemically-induced alterations in sexual and functional development : the wildlife/human connection
D. Idler (1972)
Steroids in nonmammalian vertebrates
van den Hurk van den Hurk, Slof Slof (1981)
A morphological and experimental study on gonadal sex differentiation in the rainbow trout, Salmo gairdneriCell Tissue Res, 218
J. Lech, S. Lewis, L. Ren (1996)
In vivo estrogenic activity of nonylphenol in rainbow trout.Fundamental and applied toxicology : official journal of the Society of Toxicology, 30 2
Sharpe Sharpe, Fisher Fisher, Millar Millar, Jobling Jobling, Sumpter Sumpter (1995)
Gestational and/or neonatal exposure of rats to environmental estrogenic chemicals results in reduced testicular size and sperm counts in adult lifeEnviron Health Perspect, 103
R. Johnstone, T. Simpson, A. Youngson (1979)
Sex reversal in salmonid cultureAquaculture, 13
R. Bulkley (1972)
Diethylstilbestrol in Catfish FeedTransactions of The American Fisheries Society, 101
J. Sumpter (1992)
Control of growth of rainbow trout (Oncorhynchus mykiss)Aquaculture, 100
ogenous estradiol-17b and testosterone during the early development of coho salmon (Oncorhynchus kisutch), including eggs, alevins and fry
Jobling Jobling, Sheahan Sheahan, Osborne Osborne, Matthiessen Matthiessen, Sumpter Sumpter (1996)
Inhibition of testicular growth in trout exposed to environmental estrogensEnviron Toxicol Chem, 15
Piferrer Piferrer, Donaldson Donaldson (1994)
Uptake and clearance of exogenous estradiol‐17b and testosterone during the early development of coho salmon ( Oncorhynchus kisutch ), including eggs, alevins and fryFish Physiol Biochem, 13
L. Guillette, D. Crain, Andrew Rooney, D. Pickford (1995)
Organization versus activation: the role of endocrine-disrupting contaminants (EDCs) during embryonic development in wildlife.Environmental Health Perspectives, 103
Naylor Naylor, Mieure Mieure, Adams Adams, Weeks Weeks, Castaldi Castaldi, Ogle Ogle, Romano Romano (1992)
Alkylphenol ethoxylates in the aquatic environmentJ Am Oil Chem Soc, 69
E. Stephanou, W. Giger (1982)
Persistent organic chemicals in sewage effluents. 2. Quantitative determinations of nonylphenols and nonylphenol ethoxylates by glass capillary gas chromatography.Environmental science & technology, 16 11
T. Leatherland, A. Warhurst (1995)
An Environmental Assessment of Alkylphenol Ethoxylates and AlkylphenolsJournal of Applied Ecology, 32
J. Markert, D. Higgs, H. Dye, D. MacQuarrie (1977)
Influence of bovine growth hormone on growth rate, appetite, and food conversion of yearling coho salmon (Oncorhynchus kisutch) fed two diets of different composition.Canadian journal of zoology, 55 1
Roger White, S. Jobling, S. Hoare, J. Sumpter, M. Parker (1994)
Environmentally persistent alkylphenolic compounds are estrogenic.Endocrinology, 135 1
R. Sharpe, N. Skakkebæk (1993)
Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?The Lancet, 341
J. Elliott (1990)
Mechanisms responsible for population regulation in young migratory trout, Salmo trutta. II. Fish growth and size variation.Journal of Animal Ecology, 59
M. Blackburn, M. Waldock (1995)
Concentrations of alkylphenols in rivers and estuaries in England and WalesWater Research, 29
C. Naylor, J. Mieure, W. Adams, J. Weeks, F. Castaldi, L. Ogle, R. Romano (1992)
Alkylphenol ethoxylates in the environmentJournal of the American Oil Chemists Society, 69
V. Trudeau, Gustavo Somoza, C. Nahorniak, Richard Peter (1992)
Interactions of estradiol with gonadotropin-releasing hormone and thyrotropin-releasing hormone in the control of growth hormone secretion in the goldfish.Neuroendocrinology, 56 4
Trudeau Trudeau, Somoza Somoza, Nahorniak Nahorniak, Peter Peter (1992)
Interactions of estradiol with gonadotropin‐releasing hormone in the control of growth hormone secretion in the goldfishNeuroendocrinology, 56
A. Soto, H. Justicia, Jonathan Wray, C. Sonnenschein (1991)
p-Nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene.Environmental Health Perspectives, 92
J. Sumpter, S. Jobling (1995)
Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment.Environmental Health Perspectives, 103
(1984)
Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas). Special Publication of the Center for Lake Superior Environmental Studies
S. Jobling, J. Sumpter, D. Sheahan, J. Osborne, P. Matthiessen (1996)
Inhibition of testicular growth in rainbow trout (Oncorhynchus mykiss) exposed to estrogenic alkylphenolic chemicalsEnvironmental Toxicology and Chemistry, 15
(1997)
Persistent effects of early exposure to the estrogens estradiol-17 and 17-ethynylestradiol on the gonads of the teleost Dicentrarchus labrax
(1992)
Photoperiodic control of plasma growth hormone levels and sexual maturation of adult Atlantic salmon
(1994)
Uptake and clearance of ex686 Environ
S. Jobling, J. Sumpter (1993)
Detergent components in sewage effluent are weakly oestrogenic to fish: An in vitro study using rainbow trout (Oncorhynchus mykiss) hepatocytesAquatic Toxicology, 27
R. Sharpe, J. Fisher, M. Millar, S. Jobling, J. Sumpter (1995)
Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.Environmental Health Perspectives, 103
M. Ahel, J. Mcevoy, W. Giger (1993)
Bioaccumulation of the lipophilic metabolites of nonionic surfactants in freshwater organisms.Environmental pollution, 79 3
The alkylphenol ethoxylates (APEOs) are a major group of nonionic surfactants. Biodegradation of these compounds is incomplete during sewage treatment; thus, they are ubiquitous aquatic pollutants. All the main degradation products of APEOs were recently demonstrated to have estrogenic properties in vitro, but their effects in vivo remain to be established. In this study, female juvenile rainbow trout (Oncorhynchus mykiss Walbaum) were exposed to octylphenol, nonylphenol (NP), nonylphenol diethoxylate, and nonylphenol mono‐carboxylic acid (NP1EC) at environmentally relevant concentrations (Experiment 1: 1, 10, and 50 μg/L; Experiment 2: 1, 10, and 30 μg/L). Exposure to APEOs commenced at hatch (day 0) and was terminated on day 22 (Experiment 1) or day 35 (Experiment 2). Body weight and fork length of representative samples offish from each treatment group were recorded at intervals up to 108 d (Experiment 1) or 466 d (Experiment 2). In Experiment 1, significant differences in size of the exposed fish, related to treatment, were still apparent on day 108, 86 d after withdrawal of the treatments. These observations were confirmed during Experiment 2, in which significant changes in body weight and fork length as a consequence of exposure to the compounds were observed approx. 15 d after exposure was terminated. These differences were sustained for at least 466 d in the case of NP and NP1EC. In addition, the ovosomatic index (OSI) offish exposed to NP and NP1EC was significantly affected zby the treatment. Survival of fish in the natural environment is strongly influenced by body size, and an appropriate OSI is a crucial factor in successful reproduction. Therefore, exposure of natural populations of fish to these chemicals at concentrations currently measurable in the aquatic environment may have an impact on the performance of those populations.
Environmental Toxicology & Chemistry – Wiley
Published: Apr 1, 1998
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