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P. Nielsen, G. Mcmaster, H. Trachsel (1985)
Cloning of eukaryotic protein synthesis initiation factor genes: isolation and characterization of cDNA clones encoding factor eIF-4A.Nucleic acids research, 13 19
T. Chang, J. Arenas, J. Abelson (1990)
Identification of five putative yeast RNA helicase genes.Proceedings of the National Academy of Sciences of the United States of America, 87
F. Rozen, I. Edery, K. Meerovitch, T. Dever, W. Merrick, N. Sonenberg (1990)
Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4FMolecular and Cellular Biology, 10
J. Walker, M. Saraste, M. Runswick, N. Gay (1982)
Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold.The EMBO Journal, 1
D. Dorer, A. Christensen, D. Johnson (1990)
A novel RNA helicase gene tightly linked to the Triplo-lethal locus of Drosophila.Nucleic acids research, 18 18
Jiann-Hwa Chen, R. Lin (1990)
The yeast PRP2 protein, a putative RNA-dependent ATPase, shares extensive sequence homology with two other pre-mRNA splicing factors.Nucleic acids research, 18 21
S. Schmid, P. Linder (1991)
Translation initiation factor 4A from Saccharomyces cerevisiae: analysis of residues conserved in the D-E-A-D family of RNA helicasesMolecular and Cellular Biology, 11
P. Lasko, M. Ashburner (1990)
Posterior localization of vasa protein correlates with, but is not sufficient for, pole cell development.Genes & development, 4 6
Harald Hirling, Martin Scheffner, Tobias Restle, Hans Stahl (1989)
RNA helicase activity associated with the human p68 proteinNature, 339
B. Hay, L. Jan, Y. Jan (1988)
A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicasesCell, 55
(1990)
RNA helicases from Escherichia coli to mammals
Robert Rhoads (1988)
Cap recognition and the entry of mRNA into the protein synthesis initiation cycle.Trends in biochemical sciences, 13 2
M. Kuroda, Maurice Kernan, R. Kreber, B. Ganetzky, B. Baker (1991)
The maleless protein associates with the X chromosome to regulate dosage compensation in drosophilaCell, 66
M. Company, J. Arenas, J. Abelson (1991)
Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomesNature, 349
D. Jamieson, J. Beggs (1991)
A suppressor of yeast spp81/ded1 mutations encodes a very similar putative ATP‐dependent RNA helicaseMolecular Microbiology, 5
R. Iggo, D. Jamieson, S. MacNeill, J. Southgate, J. McPheat, D. Lane (1991)
p68 RNA helicase: identification of a nucleolar form and cloning of related genes containing a conserved intron in yeastsMolecular and Cellular Biology, 11
B. Schwer, C. Guthrie (1991)
PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosomeNature, 349
M. Ford, I. Anton, D. Lane (1988)
Nuclear protein with sequence homology to translation initiation factor eIF-4ANature, 332
R. Iggo, S. Picksley, J. Southgate, J. McPheat, D. Lane (1990)
Identification of a putative RNA helicase in E.coli.Nucleic acids research, 18 18
T. Valoir, M. Tucker, E. Belikoff, L. Camp, C. Bolduc, K. Beckingham (1991)
A second maternally expressed Drosophila gene encodes a putative RNA helicase of the "DEAD box" family.Proceedings of the National Academy of Sciences of the United States of America, 88
M. Scheffner, R. Knippers, H. Stahl (1989)
RNA unwinding activity of SV40 large T antigenCell, 57
Alan Sachs, Ronald Davis (1990)
Translation initiation and ribosomal biogenesis: involvement of a putative rRNA helicase and RPL46.Science, 247 4946
Maurice Kernan, M. Kuroda, R. Kreber, B. Baker, B. Ganetzky (1991)
napts , a Mutation affecting sodium channel activity in Drosophila, Is an allele of mle a regulator of X chromosome transcriptionCell, 66
H. Stahl, Peter Droge, Rolf Knippers (1986)
DNA helicase activity of SV40 large tumor antigen.The EMBO Journal, 5
D. Jamieson, B. Rahe, J. Pringle, J. Beggs (1991)
A suppressor of a yeast splicing mutation (prp8-l) encodes a putative ATP-dependent RNA helicaseNature, 349
P. Nielsen, H. Trachsel (1988)
The mouse protein synthesis initiation factor 4A gene family includes two related functional genes which are differentially expressed.The EMBO Journal, 7
J. Couto, J. Tamm, R. Parker, C. Guthrie (1987)
A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation.Genes & development, 1 5
B. Séraphin, M. Simon, A. Boulet, G. Faye (1989)
Mitochondrial splicing requires a protein from a novel helicase familyNature, 337
R. Gururajan, H. Perry-O'Keefet, Douglas Melton, Daniel Weeks (1991)
The Xenopus localized messenger RNA An3 may encode an ATP-dependent RNA helicaseNature, 349
R. Iggo, D. Lane (1989)
Nuclear protein p68 is an RNA‐dependent ATPase.The EMBO Journal, 8
W. Toone, Kenneth Rudd, D. James, '. Friesen (1991)
deaD, a new Escherichia coli gene encoding a presumed ATP-dependent RNA helicase, can suppress a mutation in rpsB, the gene encoding ribosomal protein S2Journal of Bacteriology, 173
D. Goss, C. Woodley, A. Wahba (1987)
A fluorescence study of the binding of eucaryotic initiation factors to messenger RNA and messenger RNA analogues.Biochemistry, 26 6
S. Burgess, J. Couto, C. Guthrie (1990)
A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicingCell, 60
P. Linder, Paul Lasko, M. Ashburner, P. Leroy, Peter Nielsen, K. Nishi, J. Schnier, P. Slonimski (1989)
Birth of the D-E-A-D boxNature, 337
Florence Rozen, Jerry Pelletier, H. Trachsel, Nahum Sonenberg (1989)
A lysine substitution in the ATP-binding site of eucaryotic initiation factor 4A abrogates nucleotide-binding activityMolecular and Cellular Biology, 9
J Grifo, R. Abramson, C Satler, W. Merrick (1984)
RNA-stimulated ATPase activity of eukaryotic initiation factors.The Journal of biological chemistry, 259 13
S. Milburn, J. Hershey, M. Davies, K. Kelleher, R. Kaufman (1990)
Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif.The EMBO Journal, 9
Sonia Laín, JoséL. Riechmann, Juan García (1990)
RNA helicase: a novel activity associated with a protein encoded by a positive strand RNA virus.Nucleic acids research, 18 23
E. Strauss, Christine Guthrie (1991)
A cold-sensitive mRNA splicing mutant is a member of the RNA helicase gene family.Genes & development, 5 4
P. Leroy, P. Alzari, D. Sassoon, D. Wolgemuth, M. Fellous (1989)
The protein encoded by a murine male germ cell-specific transcript is a putative ATP-dependent RNA helicaseCell, 57
D. King, J. Beggs (1990)
Interactions of PRP2 protein with pre-mRNA splicing complexes in Saccharomyces cerevisiae.Nucleic acids research, 18 22
K. Nishi, F. Morel-Deville, J. Hershey, T. Leighton, J. Schnier (1989)
Corrigendum: An elF-4A-like protein is a suppressor of an Escherichia coli mutant defective in 5OS ribosomal subunit assemblyNature, 340
R. Abramson, T. Dever, T. Lawson, B. Ray, R. Thach, W. Merrick (1987)
The ATP-dependent interaction of eukaryotic initiation factors with mRNA.The Journal of biological chemistry, 262 8
P. Linder, A. Prat (1990)
Baker's yeast, the new work horse in protein synthesis studies: Analyzing eukaryotic translation initiationBioEssays, 12
G. Dalbadie-McFarland, John Abelson (1990)
PRP5: a helicase-like protein required for mRNA splicing in yeast.Proceedings of the National Academy of Sciences of the United States of America, 87
E. Koonin (1991)
Similarities in RNA helicasesNature, 352
P. Lasko, M. Ashburner (1988)
The product of the Drosophila gene vasa is very similar to eukaryotic initiation factor-4ANature, 335
David Lane, David Lane, W. Hoeffler (1980)
SV40 large T shares an antigenic determinant with a cellular protein of molecular weight 68,000Nature, 288
B. Ray, T. Lawson, J. Kramer, M. Cladaras, J. Grifo, R. Abramson, W. Merrick, R. Thach (1985)
ATP-dependent unwinding of messenger RNA structure by eukaryotic initiation factors.The Journal of biological chemistry, 260 12
K. Shannon, C. Guthrie (1991)
Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs.Genes & development, 5 5
P. Linder, P. Slonimski (1988)
Sequence of the genes TIF1 and TIF2 from Saccharomyces cerevisiae coding for a translation initiation factor.Nucleic acids research, 16 21
A. Gorbalenya, E. Koonin, A. Donchenko, V. Blinov (1989)
Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes.Nucleic Acids Research, 17
A. Sachs (1990)
Isolation of the lsd Mutations in Saccharomyces Cerevisiae
(1990)
Nucl Acids Res 18: 6447. Company
Summary RNA metabolism plays a central role in cell growth. It is essential to regulate RNA synthesis, processing, stability and degradation. Conformational changes in RNA are key elements in regulating cellular processes. Recently, an increasing number of putative RNA helicases from different organisms ranging from Escherichia coli to humans and viruses have been identified. They are Involved in diverse cellular functions such as RNA splicing, ribosome assembly, initiation of translation, spermatogenesis, embryogenesis, and cell growth and division. Based on sequence homologies these proteins were grouped in a family, the D‐E‐A‐D box protein family (D‐E‐A‐D = Asp‐Glu‐Ala‐Asp). Some of the better characterized members have been shown to possess ATP‐binding and hydrolysing activities as well as ATP‐dependent RNA helicase activities. Most of the genes encoding such proteins have been isolated from yeast, on which we will focus in this review. From sequence data, three of the members form a subfamily, the D‐E‐A‐H subfamily.
Molecular Microbiology – Wiley
Published: Feb 1, 1992
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