Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/annual-reviews/antioxidants-in-human-health-and-disease-fdY1lZ3GX6
References (79)
-
H. Powers, Amanda Loban, K. Silvers, A. Gibson (1995)
Vitamin C at concentrations observed in premature babies inhibits the ferroxidase activity of caeruloplasmin.Free radical research, 22 1
-
D. Flint, J. Tuminello, M. Emptage (1993)
The inactivation of Fe-S cluster containing hydro-lyases by superoxide.The Journal of biological chemistry, 268 30
-
T. Collins (1993)
Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion.Laboratory investigation; a journal of technical methods and pathology, 68 5
-
Matthew Byers, B. Bowman (2009)
Vitamin E supplements and coronary heart disease.Nutrition reviews, 51 11
-
W. Robberecht, P. Sapp, M. Viaene, D. Rosen, D. McKenna‐Yasek, J. Haines, R. Horvitz, P. Theys, Robert Brown (1994)
Rapid Communication: Cu/Zn Superoxide Dismutase Activity in Familial and Sporadic Amyotrophic Lateral SclerosisJournal of Neurochemistry, 62
-
D. Dème, J. Doussière, V. Sandro, C. Dupuy, J. Pommier, A. Virion (1994)
The Ca2+/NADPH-dependent H2O2 generator in thyroid plasma membrane: inhibition by diphenyleneiodonium.The Biochemical journal, 301 ( Pt 1)
-
B. Halliwell, J. Gutteridge, C. Cross (1992)
Free radicals, antioxidants, and human disease: where are we now?The Journal of laboratory and clinical medicine, 119 6
-
Z. Dixon, B. Burri, A. Clifford, E. Frankel, B. Schneeman, Elizabeth Parks, N. Keim, T. Barbieri, Mei‐Miau Wu, A. Fong, M. Kretsch, A. Sowell, J. Erdman (1994)
Effects of a carotene-deficient diet on measures of oxidative susceptibility and superoxide dismutase activity in adult women.Free radical biology & medicine, 17 6
-
B. Bolann, R. Ulvik (1990)
On the limited ability of superoxide to release iron from ferritin.European journal of biochemistry, 193 3
-
J. Beckman, Jun Chen, H. Ischiropoulos, J. Crow (1994)
Oxidative chemistry of peroxynitrite.Methods in enzymology, 233
-
E. Rimm, M. Stampfer, A. Ascherio, E. Giovannucci, G. Colditz, W. Willett (1993)
Vitamin E consumption and the risk of coronary heart disease in men.The New England journal of medicine, 328 20
-
D. Goldberg (1995)
Does wine work?Clinical chemistry, 41 1
-
M. Kadiiska, P. Hanna, L. Hernández, R. Mason (1992)
In vivo evidence of hydroxyl radical formation after acute copper and ascorbic acid intake: electron spin resonance spin-trapping investigation.Molecular pharmacology, 42 4
-
A. Bendich, L. Machlin, O. Scandurra, G. Burton, D. Wayner (1986)
The antioxidant role of vitamin CAdvances in Free Radical Biology & Medicine, 2
-
M. Gurney, Haifeng (Pu), A. Chiu, M. Canto, C. Polchow, D. Alexander, J. Caliendo, A. Hentati, Y. Kwon, H. Deng (1994)
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.Science, 264 5166
-
K. Maddipati, L. Marnett (1987)
Characterization of the major hydroperoxide-reducing activity of human plasma. Purification and properties of a selenium-dependent glutathione peroxidase.The Journal of biological chemistry, 262 36
-
B. Halliwell, J. Gutteridge (1990)
Role of free radicals and catalytic metal ions in human disease: an overview.Methods in enzymology, 186
-
H. Berger, S. Mumby, J. Gutteridge (1995)
Ferrous ions detected in iron-overloaded cord blood plasma from preterm and term babies: implications for oxidative stress.Free radical research, 22 6
-
G. Poppel, H. Poulsen, S. Loft, H. Verhagen (1995)
No influence of beta carotene on oxidative DNA damage in male smokers.Journal of the National Cancer Institute, 87 4
-
G. Burton, M. Traber (1990)
Vitamin E: antioxidant activity, biokinetics, and bioavailability.Annual review of nutrition, 10
-
L. Candeias, K. Patel, M. Stratford, P. Wardman (1993)
Free hydroxyl radicals are formed on reaction between the neutrophil‐derived species Superoxide anion and hypochlorous acidFEBS Letters, 333
-
N. Das (1971)
Studies on flavonoid metabolism. Absorption and metabolism of (+)-catechin in man.Biochemical pharmacology, 20 12
-
W. Porter (1993)
Paradoxical Behavior of Antioxidants in Food and Biological SystemsToxicology and Industrial Health, 9
-
B. Demple, L. Harrison (1994)
Repair of oxidative damage to DNA: enzymology and biology.Annual review of biochemistry, 63
-
Ian Johnson, Gary Williamson, S. Musk (1994)
Anticarcinogenic Factors in Plant Foods: A New Class of Nutrients?Nutrition Research Reviews, 7
-
B. Chance, H. Sies, A. Boveris (1979)
Hydroperoxide metabolism in mammalian organs.Physiological reviews, 59 3
-
H. Rubbo, R. Radi, M. Trujillo, R. Telleri, B. Kalyanaraman, S. Barnes, Marion Kirk, B. Freeman (1994)
Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives.The Journal of biological chemistry, 269 42
-
M. Dizdaroglu, Z. Nackerdien, B. Chao, E. Gajewski, G. Rao (1991)
Chemical nature of in vivo DNA base damage in hydrogen peroxide-treated mammalian cells.Archives of biochemistry and biophysics, 285 2
-
P. Evans, R. Evans, I. Kovar, A. Holton, B. Halliwell (1992)
Bleomycin‐detectable iron in the plasma of premature and full‐term neonatesFEBS Letters, 303
-
A. Vliet, D. Smith, C. O'Neill, H. Kaur, V. Darley-Usmar, C. Cross, B. Halliwell, B. Halliwell (1994)
Interactions of peroxynitrite with human plasma and its constituents: oxidative damage and antioxidant depletion.The Biochemical journal, 303 ( Pt 1)
-
A. Slivka, J. Kang, G. Cohen (1986)
Hydroxyl radicals and the toxicity of oral iron.Biochemical pharmacology, 35 4
-
S. Harel, Menahem Salan, J. Kanner (1988)
Iron release from metmyoglobin, methaemoglobin and cytochrome c by a system generating hydrogen peroxide.Free radical research communications, 5 1
-
J. Iqbal, L. Clerch, M. Hass, L. Frank, D. Massaro (1989)
Endotoxin increases lung Cu,Zn superoxide dismutase mRNA: O2 raises enzyme synthesis.The American journal of physiology, 257 2 Pt 1
-
J. Morrow, L. Roberts (1994)
Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism.Methods in enzymology, 233
-
A. Laires, J. Gaspar, H. Borba, M. Proença, M. Monteiro, J. Rueff (1993)
Genotoxicity of nitrosated red wine and of the nitrosatable phenolic compounds present in wine: tyramine, quercetin and malvidine-3-glucoside.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 31 12
-
J. Cook, B. Skikne, S. Lynch, M. Reusser (1986)
Estimates of iron sufficiency in the US population.Blood, 68 3
-
R. Moison, J. Palinckx, M. Roest, E. Houdkamp, H. Berger (1993)
Induction of lipid peroxidation of pulmonary surfactant by plasma of preterm babiesThe Lancet, 341
-
B. Babior, Woodman Rc (1990)
Chronic granulomatous disease.Advances in human genetics, 16
-
V. Kagan, V. Kagan, E. Serbinova, E. Serbinova, L. Packer, L. Packer (1990)
Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling.Biochemical and biophysical research communications, 169 3
-
B. Halliwell (2009)
Free radicals and antioxidants: a personal view.Nutrition reviews, 52 8 Pt 1
-
M. Hertog, E. Feskens, P. Hollman, M. Katan, D. Kromhout (1993)
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly StudyThe Lancet, 342
-
F. Ursini, A. Bindoli (1987)
The role of selenium peroxidases in the protection against oxidative damage of membranes.Chemistry and physics of lipids, 44 2-4
-
D. Steinberg, S. Parthasarathy, T. Carew, J. Khoo, J. Witztum (1989)
Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.The New England journal of medicine, 320 14
-
N. Krinsky (1993)
Actions of carotenoids in biological systems.Annual review of nutrition, 13
-
P. Brennan, L. O’Neill (1995)
Effects of oxidants and antioxidants on nuclear factor kappa B activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals.Biochimica et biophysica acta, 1260 2
-
D. Wilhelm-Filho, B. González-Flecha, A. Boveris (1994)
Gill diffusion as a physiological mechanism for hydrogen peroxide elimination by fish.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 27 12
-
O. Aruoma, Barry Halliwell, E. Gajewski, M. Dizdaroglu (1991)
Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide.The Biochemical journal, 273 ( Pt 3)
-
P. Hyslop, Daniel, Hinshawz, Wayne Halsey, Ingrid, Schraufstatter, Richard Sauerhebery, Roger Spraggj, Janis Jackson, C Cochrane (1988)
Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.The Journal of biological chemistry, 263 4
-
W. Willett (1994)
Diet and health: what should we eat?Science, 264 5158
-
J. Swain, V. Darley-Usmar, J. Gutteridge (1994)
Peroxynitrite releases copper from caeruloplasmin: implications for atherosclerosisFEBS Letters, 342
-
D. Touati (1991)
The molecular genetics of superoxide dismutase in E. coli.Free radical research communications, 12-13 Pt 1
-
M. Burt, J. Halliday, L. Powell (1993)
Iron and coronary heart disease.British Medical Journal, 307
-
R. Huie, S. Padmaja (1993)
The reaction of no with superoxide.Free radical research communications, 18 4
-
H. Esterbauer, G. Striegl, H. Puhl, M. Rotheneder (2009)
Continuous Monitoring of in Vztro Oxidation of Human Low Density Lipoprotein, 6
-
D. Touati (1989)
The molecular genetics of superoxide dismutase in E. coli. An approach to understanding the biological role and regulation of SODS in relation to other elements of the defence system against oxygen toxicity.Free radical research communications, 8 1
-
R. Schreck, K. Albermann, P. Baeuerle (1992)
Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review), 17
-
R. Olinski, T. Zastawny, J. Budzbon, J. Skokowski, Wojtek Zegarski, M. Dizdaroglu (1992)
DNA base modifications in chromatin of human cancerous tissuesFEBS Letters, 309
-
S. Loft, A. Astrup, B. Buemann, H. Poulsen (1994)
Oxidative DNA damage correlates with oxygen consumption in humansThe FASEB Journal, 8
-
C. McLaran, J. Bett, J. Nye, J. Halliday (1982)
Congestive cardiomyopathy and haemochromatosis--rapid progression possibly accelerated by excessive ingestion of ascorbic acid.Australian and New Zealand journal of medicine, 12 2
-
S. Orrenius, D. McConkey, G. Bellomo, P. Nicotera (1989)
Role of Ca2+ in toxic cell killing.Trends in pharmacological sciences, 10 7
-
P. Jenner (1994)
Oxidative damage in neurodegenerative diseaseThe Lancet, 344
-
C. Smith, C. Smith, M. Mitchinson, M. Mitchinson, O. Aruoma, O. Aruoma, B. Halliwell, B. Halliwell (1992)
Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions.The Biochemical journal, 286 ( Pt 3)
-
F. Laurindo, P. Luz, L. Uint, Tania Rocha, R. Jaeger, Edgard Lopes (1991)
Evidence for Superoxide Radical–Dependent Coronary Vasospasm After Angioplasty in Intact DogsCirculation, 83
-
J. Balentine (1982)
Pathology of Oxygen Toxicity -
T. Grune, T. Reinheckel, M. Joshi, K. Davies (1995)
Proteolysis in Cultured Liver Epithelial Cells during Oxidative StressThe Journal of Biological Chemistry, 270
-
Yin Zhang, Yin Zhang, O. Marcillat, C. Giulivi, L. Ernster, L. Ernster, K. Davies (1990)
The oxidative inactivation of mitochondrial electron transport chain components and ATPase.The Journal of biological chemistry, 265 27
-
M. Traber, R. Sokol, S. Ringel, H. Neville, C. Thellman, H. Kayden (1987)
Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy.The New England journal of medicine, 317 5
-
J. Totter (1980)
Spontaneous cancer and its possible relationship to oxygen metabolism.Proceedings of the National Academy of Sciences of the United States of America, 77 4
-
G. Block, B. Patterson, A. Subar (1992)
Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence.Nutrition and cancer, 18 1
-
O. Aruoma, B. Halliwell (1987)
Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl-radical generation?The Biochemical journal, 241 1
-
Wendy Fish, M. Cohen, D. Franzek, Janice Williams, J. Lemons (1990)
Effect of intramuscular vitamin E on mortality and intracranial hemorrhage in neonates of 1000 grams or less.Pediatrics, 85 4
-
D. Granger (1988)
Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury.The American journal of physiology, 255 6 Pt 2
-
Xiang‐Dong Wang, G. Tang, J. Fox, N. Krinsky, R. Russell (1991)
Enzymatic conversion of β-carotene into β-apo-carotenals and retinoids by human, monkey, ferret, and rat tissuesArchives of Biochemistry and Biophysics, 285
-
Monsen Meydani, Antonio Martin, J. Ribaya-Mercado, Junxian Gong, Jeffrey Blumberg, Robert Russell (1994)
Beta-carotene supplementation increases antioxidant capacity of plasma in older women.The Journal of nutrition, 124 12
-
B. Ames, M. Shigenaga, T. Hagen (1993)
Oxidants, antioxidants, and the degenerative diseases of aging.Proceedings of the National Academy of Sciences of the United States of America, 90 17
-
C. Edwards, L. Griffen, D. Goldgar, C. Drummond, M. Skolnick, J. Kushner (1988)
Prevalence of hemochromatosis among 11,065 presumably healthy blood donors.The New England journal of medicine, 318 21
-
J. Spencer, A. Jenner, O. Aruoma, P. Evans, H. Kaur, D. Dexter, P. Jenner, A. Lees, D. Marsden, B. Halliwell (1994)
Intense oxidative DNA damage promoted by l‐DOPA and its metabolites implications for neurodegenerative diseaseFEBS Letters, 353
-
B. Halliwell, J. Gutteridge (1985)
Free radicals in biology and medicine -
B. Rowbotham, H. Roeser (1984)
Iron overload associated with congenital pyruvate kinase deficiency and high dose ascorbic acid ingestion.Australian and New Zealand journal of medicine, 14 5
- Publisher
- Annual Reviews
- Copyright
- Copyright 1996 Annual Reviews. All rights reserved
- Subject
- Review Articles
- ISSN
- 0199-9885
- eISSN
- 1545-4312
- DOI
- 10.1146/annurev.nu.16.070196.000341
- pmid
- 8839918
- Publisher site
- See Article on Publisher Site
Abstract
Free radicals and antioxidants are widely discussed in the clinical and nutritional literature. Antioxidants are needed to prevent the formation and oppose the actions of reactive oxygen and nitrogen species, which are generated in vivo and cause damage to DNA, lipids, proteins, and other biomolecules. Endogenous antioxidant defenses (superoxide dismutases, H 2 O 2 -removing enzymes, metal binding proteins) are inadequate to prevent damage completely, so dietderived antioxidants are important in maintaining health. Many dietary compounds have been suggested to be important antioxidants: The evidence for a key role of vitamins E and C is strong, but that for carotenoids and related plant pigments is weaker. Interest is also growing in the role of plant phenolics, especially flavonoids. Some antioxidants can exert prooxidant effects in vitro, but their physiological relevance is uncertain. Experimental approaches to the optimization of antioxidant nutrient intake are proposed.
Journal
Annual Review of Nutrition – Annual Reviews
Published: Jul 1, 1996