Access the full text.
Sign up today, get DeepDyve free for 14 days.
I. Chapman, E. Goble, G. Wittert, M. Horowitz (1999)
Effects of small-intestinal fat and carbohydrate infusions on appetite and food intake in obese and nonobese men.The American journal of clinical nutrition, 69 1
F. Mearin, M. Cucala, F. Azpiroz, J. Malagelada (1991)
The origin of symptoms on the brain-gut axis in functional dyspepsia.Gastroenterology, 101 4
William Brener, T. Hendrix, P. McHugh (1983)
Regulation of the gastric emptying of glucose.Gastroenterology, 85 1
C. Feinle, David Grundy, N. Read (1997)
Effects of duodenal nutrients on sensory and motor responses of the human stomach to distension.The American journal of physiology, 273 3 Pt 1
C. Feinle, O. Meier, B. Otto, M. D'Amato, M. Fried (2001)
Role of duodenal lipid and cholecystokinin A receptors in the pathophysiology of functional dyspepsiaGut, 48
M. Fried, E. Mayer, J. Jansen, C. Lamers, I. Taylor, S. Bloom, J. Meyer (1988)
Temporal relationships of cholecystokinin release, pancreatobiliary secretion, and gastric emptying of a mixed meal.Gastroenterology, 95 5
J. Kleibeuker, H. Beekhuis, J. Jansen, D. Piers, C. Lamers (1988)
Cholecystokinin is a physiological hormonal mediator of fat‐induced inhibition of gastric emptying in manEuropean Journal of Clinical Investigation, 18
T. Lutz, S. Tschudy, P. Rushing, E. Scharrer (2000)
Attenuation of the anorectic effects of cholecystokinin and bombesin by the specific amylin antagonist AC 253Physiology & Behavior, 70
H. Lin, J. Doty, T. Reedy, J. Meyer (1990)
Inhibition of gastric emptying by sodium oleate depends on length of intestine exposed to nutrient.The American journal of physiology, 259 6 Pt 1
Karen Cunningham, R. Baker, M. Horowitz, A. Maddox, M. Edelbroek, B. Chatterton, MD Datz (1991)
Use of technetium-99m(V)thiocyanate to measure gastric emptying of fat.Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 32 5
Barbera Barbera, Feinle Feinle, Read Read (1995)
Nutrient‐specific modulation of gastric mechano‐sensitivity in patients with functional dyspepsiaDig Dis Sci, 40
C. Cook, Jane Andrews, Karen Jones, Gary Wittert, Ian Chapman, John Morley, Michael Horowitz (1997)
Effects of small intestinal nutrient infusion on appetite and pyloric motility are modified by age.The American journal of physiology, 273 2 Pt 2
J. Gutzwiller, B. Göke, J. Drewe, P. Hildebrand, S. Ketterer, D. Handschin, R. Winterhalder, D. Conen, C. Beglinger (1999)
Glucagon-like peptide-1: a potent regulator of food intake in humansGut, 44
Raybould Raybould, Zittel Zittel, Hölzer Hölzer, Lloyd Lloyd, Meyer Meyer (1994)
Gastroduodenal sensory mechanisms and CCK in inhibition of gastric emptying in response to a mealDig Dis Sci, 39
S. Miaskiewicz, E. Stricker, J. Verbalis (1989)
Neurohypophyseal secretion in response to cholecystokinin but not meal-induced gastric distention in humans.The Journal of clinical endocrinology and metabolism, 68 4
(2001)
Symptomatic and plasma CCK responses to increasing doses of duodenal lipid in patients with functional dyspepsia (FD) and the role of CCK-A receptors
antagonist loxiglumide, R. Lieverse, J. Jansen, A. Masclee, L. Rovati, C. Lamers (1994)
Effect of a low dose of intraduodenal fat on satiety in humans: studies using the type A cholecystokinin receptor antagonist loxiglumide.Gut, 35
J. Schirra, P. Houck, U. Wank, R. Arnold, Burkhard Göke, M. Katschinski (2000)
Effects of glucagon-like peptide-1(7-36)amide on antro-pyloro-duodenal motility in the interdigestive state and with duodenal lipid perfusion in humansGut, 46
C. Cheng, J. Geoghegan, D. Lawson, S. Berlangieri, O. Akwari, T. Pappas (1993)
Central and peripheral effects of CCK receptor antagonists on satiety in dogs.The American journal of physiology, 265 2 Pt 1
P. Gregory, M. McFadyen, D. Rayner (1989)
Duodenal infusion of fat, cholecystokinin secretion and satiety in the pigPhysiology & Behavior, 45
P. Maton, A. Selden, V. Chadwick (1982)
Large and small forms of cholecystokinin in human plasma: measurement using high pressure liquid chromatography and radioimmunoassayRegulatory Peptides, 4
K. Jones, S Doran, K. Hveem, F. Bartholomeusz, J Morley, W Sun, B. Chatterton, M. Horowitz (1997)
Relation between postprandial satiation and antral area in normal subjects.The American journal of clinical nutrition, 66 1
M. Kong, T. Stubbs, P. King, I. Macdonald, J. Lambourne, P. Blackshaw, A. Perkins, R. Tattersall (1998)
The effect of single doses of pramlintide on gastric emptying of two meals in men with IDDMDiabetologia, 41
S. Peikin (1989)
Role of cholecystokinin in the control of food intake.Gastroenterology clinics of North America, 18 4
D. Matzinger, Lukas Degen, Jürgen Drewe, J. Meuli, R. Duebendorfer, N. Ruckstuhl, Massimo D'Amato, L. Rovati, C. Beglinger (2000)
The role of long chain fatty acids in regulating food intake and cholecystokinin release in humansGut, 46
G. Shillabeer, J. Davison (1984)
The cholecystokinin antagonist, proglumide, increases food intake in the ratRegulatory Peptides, 8
C. Sepple, N. Read (1989)
Gastrointestinal correlates of the development of hunger in manAppetite, 13
F. Azpiroz, J. Malagelada (1985)
Intestinal control of gastric tone.The American journal of physiology, 249 4 Pt 1
J. Straathof, B. Mearadji, C. Lamers, A. Masclee (1998)
Effect of CCK on proximal gastric motor function in humans.American journal of physiology. Gastrointestinal and liver physiology, 274 5
C. Eastwood, K. Maubach, A. Kirkup, D. Grundy (1998)
The role of endogenous cholecystokinin in the sensory transduction of luminal nutrient signals in the rat jejunumNeuroscience Letters, 254
C. Feinle, David Grundy, Bärbel Otto, Michael Fried (2000)
Relationship between increasing duodenal lipid doses, gastric perception, and plasma hormone levels in humans.American journal of physiology. Regulatory, integrative and comparative physiology, 278 5
(2000)
Relationship between increasing doses of duodenal lipid, gastric perception and plasma hormone responses in humans
R. Lieverse, J. Jansen, C. Lamers (1993)
Cholecystokinin and satiation.The Netherlands journal of medicine, 42 3-4
W. Hopman, J. Jansen, C. Lamers (1985)
Comparative study of the effects of equal amounts of fat, protein, and starch on plasma cholecystokinin in man.Scandinavian journal of gastroenterology, 20 7
F. Azpiroz, J. Malagelada (1987)
Gastric tone measured by an electronic barostat in health and postsurgical gastroparesis.Gastroenterology, 92 4
J. Verbalis, D. Richardson, E. Stricker (1987)
Vasopressin release in response to nausea-producing agents and cholecystokinin in monkeys.The American journal of physiology, 252 4 Pt 2
A. Lindén, M. Carlquist, And HANSEN, K. UVNAS-MOBERG (1989)
Plasma concentrations of cholecystokinin, CCK-8, and CCK-33, 39 in rats, determined by a method based on enzyme digestion of gastrin before HPLC and RIA detection of CCK.Gut, 30
L. Brenner, D. Yox, Robert Ritter (1993)
Suppression of sham feeding by intraintestinal nutrients is not correlated with plasma cholecystokinin elevation.The American journal of physiology, 264 5 Pt 2
G. Hebbard, M. Samsom, W. Sun, J. Dent, M. Horowitz (1996)
Hyperglycemia affects proximal gastric motor and sensory function during small intestinal triglyceride infusion.The American journal of physiology, 271 5 Pt 1
J. Wishart, M. Horowitz, H. Morris, Karen Jones, M. Nauck (1998)
Relation between gastric emptying of glucose and plasma concentrations of glucagon-like peptide-1Peptides, 19
C. Rayner, H. Park, J. Wishart, M. Kong, S. Doran, M. Horowitz (2000)
Effects of intraduodenal glucose and fructose on antropyloric motility and appetite in healthy humans.American journal of physiology. Regulatory, integrative and comparative physiology, 278 2
(1996)
CCK-A receptors modulate gastric sensory and motor responses to gastric distension and duodenal lipid
R. Riepl, F. Fiedler, M. Ernstberger, J. Teufel, P. Lehnert (1996)
Effect of intraduodenal taurodeoxycholate and L-phenylalanine on pancreatic secretion and on gastroenteropancreatic peptide release in man.European journal of medical research, 1 11
K. Hveem, K. Jones, B. Chatterton, M. Horowitz (1996)
Scintigraphic measurement of gastric emptying and ultrasonographic assessment of antral area: relation to appetite.Gut, 38
B. Mearadji, A. Masclee, W. Onkenhout, I. Biemond, C. Lamers (2000)
Effect of Intraduodenal and Intravenous Amino Acids on Proximal Gastric Motor Function in ManDigestive Diseases and Sciences, 46
James Meyer, M. Hlinka, Y. Tabrizi, N. DiMaso, Helen Raybould (1998)
Chemical specificities and intestinal distributions of nutrient-driven satiety.American journal of physiology. Regulatory, integrative and comparative physiology, 275 4
R. Liddle, I. Goldfine, M. Rosen, R. Taplitz, J. Williams (1985)
Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction.The Journal of clinical investigation, 75 4
J. Tack, D. Broeckaert, B. Coulie, J. Janssens (1998)
The influence of cisapride on gastric tone and the perception of gastric distensionAlimentary Pharmacology & Therapeutics, 12
C. Feinle, M. D'Amato, N. Read (1996)
Cholecystokinin-A receptors modulate gastric sensory and motor responses to gastric distension and duodenal lipid.Gastroenterology, 110 5
Lemann Lemann, Dedering Dedering, Franchisseur Franchisseur, Rambaud Rambaud, Jian Jian (1991)
Abnormal perception of visceral pain in response to gastric distension in chronic idiopathic dyspepsiaDig Dis Sci, 36
Duodenal fat modulates sensory and motor responses to gastric distension and raises plasma cholecystokinin compared with glucose. The effects of protein (also releasing cholecystokinin), or mixed nutrients (with a balanced macronutrient composition), on gastrointestinal sensations in relation to gastric relaxation and plasma cholecystokinin concentrations are not known. The aim of this study was therefore to compare the effects of duodenal infusion of fat, protein or mixed nutrients during sustained gastric distension (mimicking the intragastric presence of food) on these parameters. In 10 healthy subjects, gastric distension to fullness was maintained for 90 min, while gastric volume, sensations and plasma cholecystokinin were monitored during duodenal infusion of isotonic saline or nutrients (2 kcal min−1). During saline infusion, all parameters remained unchanged for 90 min. Initially, only lipid increased plasma cholecystokinin, gastric volume and scores for sensations. Cholecystokinin and gastric volume responses to protein and mixed nutrients were delayed and not associated with significant changes in sensations. In conclusion, the intensity of gastrointestinal sensations is related to, but not entirely explained by, the magnitude in intragastric volume and plasma cholecystokinin changes. Our results offer new insights into the role of dietary nutrient composition in gastrointestinal sensations, and may have implications for the dietary management of digestive symptoms.
Neurogastroenterology & Motility – Wiley
Published: Apr 1, 2002
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.