Access the full text.
Sign up today, get DeepDyve free for 14 days.
R. Hille (1996)
The mononuclear molybdenum enzymesCalifornia Agric. Exp. St. Circ., 96
H. Sekimoto, M. Seo, N. Dohmae, K. Takio, Y. Kamiya, T. Koshiba (1997)
Cloning and molecular characterization of plant aldehyde oxidasePlant J., 272
H. Sekimoto, M. Seo, N. Kawakami, T. Komano, S. Desloire, S. Liotenberg, A. Marion‐Poll, M. Caboche, Y. Kamyia, T. Koshiba (1998)
Molecular cloning and characterization of aldehyde oxidases in Arabidopsis thalianaProc. Natl Acad. Sci. USA, 39
H. Bais, R. Vepachedu, S. Gilroy, R. Callaway, J. Vivanco (2003)
Allelopathy and Exotic Plant Invasion: From Molecules and Genes to Species InteractionsScience, 301
M.M. Bradford (1976)
A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principal of protein‐dye bindingJ. Biol. Chem., 72
S.J. Clough, A.F. Bent (1998)
Floral dip: a simplified method for Agrobacterium‐mediated transformation of Arabidopsis thalianaPlant Physiol., 16
J. Badwey, J. Robinson, M. Karnovsky, M. Karnovsky (1981)
Superoxide production by an unusual aldehyde oxidase in guinea pig granulocytes. Characterization and cytochemical localization.The Journal of biological chemistry, 256 7
S. Neill, R. Desikan, J. Hancock (2002)
Hydrogen peroxide signalling.Current opinion in plant biology, 5 5
R. Wright, Daniel Clayton, Mary Riley, J. McManaman, J. Repine (1999)
cDNA Cloning, Sequencing, and Characterization of Male and Female Rat Liver Aldehyde Oxidase (rAOX1)The Journal of Biological Chemistry, 274
M. Seo, A.J. Peeters, H. Koiwai, T. Oritani, A. Marion‐Poll, J.A.D. Zeevaart, M. Koornneef, Y. Kamiya, T. Koshiba (2000b)
The Arabidopsis aldehyde oxidase 3 (AAO3) gene product catalyzes the final step in abscisic acid biosynthesis in leavesPlant Physiol., 97
G. Manchenko (1994)
Handbook of Detection of Enzymes on Electrophoretic Gels
Xiang Min, K. Okada, B. Brockmann, T. Koshiba, Y. Kamiya (2000)
Molecular cloning and expression patterns of three putative functional aldehyde oxidase genes and isolation of two aldehyde oxidase pseudogenes in tomato.Biochimica et biophysica acta, 1493 3
Harry Ahles (1953)
Hordeum vulgare L.
P. Hasegawa, R. Bressan, Jian‐Kang Zhu, H. Bohnert (2000)
PLANT CELLULAR AND MOLECULAR RESPONSES TO HIGH SALINITY.Annual review of plant physiology and plant molecular biology, 51
Hauke Hansen, Klaus Grossmann (2000)
Auxin-induced ethylene triggers abscisic acid biosynthesis and growth inhibition.Plant physiology, 124 3
M. Sagi, Olga Davydov, S. Orazova, Zhazira Yesbergenova, R. Ophir, J. Stratmann, R. Fluhr (2004)
Plant Respiratory Burst Oxidase Homologs Impinge on Wound Responsiveness and Development in Lycopersicon esculentum Online version contains Web-only data.The Plant Cell Online, 16
P. Schopfer, A. Liszkay, M. Bechtold, G. Frahry, A. Wagner (2002)
Evidence that hydroxyl radicals mediate auxin-induced extension growthPlanta, 214
H.J. Bohnert, R.G. Jensen (1996)
Strategies for engineering water stress tolerance in plantsAnal. Biochem., 14
P.M. Hasegawa, R.A. Bressan, J.K. Zhu, H.J. Bohnert (2000)
Plant cellular and molecular responses to high salinityBiochem. J., 51
Zhiguang Zhao, Guo-cang Chen, Cheng-lie Zhang (2001)
Interaction between reactive oxygen species and nitric oxide in drought-induced abscisic acid synthesis in root tips of wheat seedlingsFunctional Plant Biology, 28
M. Sagi, C. Scazzocchio, R. Fluhr (2002)
The absence of molybdenum cofactor sulfuration is the primary cause of the flacca phenotype in tomato plantsEur. J. Biochem., 31
R.S. Bandurski, J.D. Cohen, J. Slovin, D.M. Reinecke (1995)
Plant Hormones: Physiology, Biochemistry and Molecular BiologyJ. Biol. Chem.
P. Montalbini (1992)
Inhibition of hypersensitive response by allopurinol applied to the host in the incompatible relationship between Phaseolus vulgaris and Uromyces phaseoliJournal of Phytopathology, 134
S. Chakraborty, V. Massey (2002)
Reaction of Reduced Flavins and Flavoproteins with Diphenyliodonium Chloride*The Journal of Biological Chemistry, 277
Green (1995)
10.2307/3869996Plant Cell, 7
R. Green, R. Fluhr (1995)
UV-B-Induced PR-1 Accumulation Is Mediated by Active Oxygen Species.The Plant cell, 7
S. A.‐H.‐Mackerness, C. John, B. Jordan, B. Thomas (2001)
Early signaling components in ultraviolet‐B responses: distinct roles for different reactive oxygen species and nitric oxideFEBS Letters, 489
L. Xiong, M. Ishitani, H. Lee, K.J. Zhu (2001)
The Arabidopsis LOS5/ABA3 locus encodes a molybdenum cofactor sulfurase and modulates cold stress‐and osmotic stress‐responsive gene expressionJ. Exp. Bot., 13
E. Zdunek, S. Lips (2001)
Transport and accumulation rates of abscisic acid and aldehyde oxidase activity in Pisum sativum L. in response to suboptimal growth conditions.Journal of experimental botany, 52 359
S.A.‐H. Mackerness, C.F. John, B. Jordan, B. Thomas (2001)
Early signaling components in ultraviolet‐B responses: distinct role for different reactive oxygen species and nitric oxidePlant Physiol. Biochem., 489
Hille (1996)
10.1021/cr950061tChem. Rev., 96
M. Seo, Anton Peeters, H. Koiwai, Takayuki Oritani, A. Marion-Poll, J. Zeevaart, Maarten Koornneef, Yuji Kamiya, T. Koshiba (2000)
The Arabidopsis aldehyde oxidase 3 (AAO3) gene product catalyzes the final step in abscisic acid biosynthesis in leaves.Proceedings of the National Academy of Sciences of the United States of America, 97 23
Steven Schwartz, K. Léon-Kloosterziel, Maarten Koornneef, J. Zeevaart (1997)
Biochemical Characterization of the aba2 and aba3 Mutants in Arabidopsis thaliana, 114
L. Xiong, Hojoung Lee, M. Ishitani, Jian‐Kang Zhu (2002)
Regulation of Osmotic Stress-responsive Gene Expression by theLOS6/ABA1 Locus inArabidopsis *The Journal of Biological Chemistry, 277
L. Xiong, M. Ishitani, Hojoung Lee, Jian‐Kang Zhu (2001)
The Arabidopsis LOS5/ABA3 Locus Encodes a Molybdenum Cofactor Sulfurase and Modulates Cold Stress– and Osmotic Stress–Responsive Gene ExpressionThe Plant Cell Online, 13
E. Marín, A. Marion-Poll (1997)
Tomato flacca mutant is impaired in ABA aldehyde oxidase and xanthine dehydrogenase activitiesPlant Physiology and Biochemistry, 35
P. Montalbini (1992a)
Inhibition of hypersensitive response by allopurinol applied to the host in the incompatible relationship between Phaseolus vulgaris and Uromyces phaseoliCurr. Opin. Plant Biol., 134
A. Fath, P. Bethke, Russell Jones (2001)
Enzymes that scavenge reactive oxygen species are down-regulated prior to gibberellic acid-induced programmed cell death in barley aleurone.Plant physiology, 126 1
N. Ori, Y. Eshed, Patricia Pinto, I. Paran, D. Zamir, R. Fluhr (1997)
TAO1, a Representative of the Molybdenum Cofactor Containing Hydroxylases from Tomato*The Journal of Biological Chemistry, 272
M. Deng, T. Moureaux, M. Caboche (1989)
Tungstate, a molybdate analog inactivating nitrate reductase, deregulates the expression of the nitrate reductase structural gene.Plant physiology, 91 1
Xing-Yu Jiang, R. Omarov, S. Yesbergenova, M. Sagi (2004)
The effect of molybdate and tungstate in the growth medium on abscisic acid content and the Mo-hydroxylases activities in barley (Hordeum vulgare L.)Plant Science, 167
M. Seo, H. Koiwai, S. Akaba, T. Komano, T. Oritani, Y. Kamiya, T. Koshiba (2000)
Abscisic aldehyde oxidase in leaves of Arabidopsis thaliana.The Plant journal : for cell and molecular biology, 23 4
Xiao Zhang, Lin Zhang, Facai Dong, J. Gao, D. Galbraith, C. Song (2001)
Hydrogen peroxide is involved in abscisic acid-induced stomatal closure in Vicia faba.Plant physiology, 126 4
P. Montalbini (1992b)
Ureides and enzymes of ureide synthesis in wheat seeds and leaves and effect of allopurinol on Puccinia recondita f. sp. Tritici infectionPhysiol. Veg., 87
R. Harrison (2002)
Structure and function of xanthine oxidoreductase: where are we now?Free radical biology & medicine, 33 6
M. Sagi, C. Scazzocchio, R. Fluhr (2002)
The absence of molybdenum cofactor sulfuration is the primary cause of the flacca phenotype in tomato plants.The Plant journal : for cell and molecular biology, 31 3
A. Fath, P.C. Bethke, R.L. Jones (2001)
Enzymes that scavenge reactive oxygen species are down‐regulated prior to gibberellic acid‐induced programmed cell death in barley aleuroneClin. Chem., 126
L.M. Guan, J. Zhao, J.G. Scadalios (2000)
Cis‐elements and trans‐factors that regulate expression of the maize Cat1 antioxidant gene in response to ABA and osmotic stress: H2O2 is the likely intermediary signaling molecule for the responsePlant Physiol., 22
F. Bittner, M. Oreb, R.R. Mendel (2001)
ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thalianaTrends Biotechnol., 276
C.M. Harris, V. Massey (1997)
The oxidative half‐reaction of xanthine dehydrogenase with NAD; reaction kinetics and steady‐state mechanismFree Radic. Biol Med., 272
M. Walker‐Simmons, D.A. Kudrna, R.L. Warner (1989)
Reduced accumulation of ABA during water stress in a molybdenum cofactor mutant of barleyPlant Cell, 90
Omarov (1998)
10.1093/jexbot/49.322.897J. Exp. Bot., 49
D. Hoagland, D. Arnon (2018)
The Water-Culture Method for Growing Plants Without Soil
L. Xiong, H. Lee, M. Ishitani, J.K. Zhu (2002b)
Regulation of osmotic stress‐responsive gene expression by the LOS6/ABA1locus in ArabidopsisAust. J. Plant Physiol., 277
M. Bradford (1976)
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.Analytical biochemistry, 72
H.R. Mirsa, I. Fridovich (1972)
The univalent reduction of oxygen by reduced flavins and quinonesPlant Sci., 247
H. Misra, I. Fridovich (1972)
The univalent reduction of oxygen by reduced flavins and quinones.The Journal of biological chemistry, 247 1
R. Omarov, M. Sagi, S. Lips (1998)
Regulation of aldehyde oxidase and nitrate reductase in roots of barley (Hordeum vulgare L.) by nitrogen source and salinityJournal of Experimental Botany, 49
X. Jiang, R.T. Omarov, Z. Yesbergenova, M. Sagi (2004)
The effect of molybdate and tungstate in the growth medium on abscisic acid content and the Mo‐hydroxylases activities in barley (Hordeum vulgare L.)Plant Physiol., 167
A. Marin, A. Marion‐Poll (1997)
Tomato flacca mutant is impaired in ABA aldehyde oxidase and xanthine dehydrogenase activitiesBiochem. Physiol. Pflanz., 35
A. Glatigny, C. Scazzocchio (1995)
Cloning and molecular characterization of hxA, the gene coding for xanthine dehydrogenase (purine hydroxylase I) of Aspergillus nidulansPlant Cell, 270
G. Pastori, L. Río (1997)
Natural Senescence of Pea Leaves (An Activated Oxygen-Mediated Function for Peroxisomes), 113
P. Fossati, L. Prencipe, G. Berti (1980)
Use of 3,5‐dichloro‐2‐hydroxybenzenesulfonic acid/4‐aminophenazone chromogenic system in direct enzymic assay of uric acid in serum and urineJ. Biol. Chem., 26
L. Guan, J. Zhao, J. Scandalios (2000)
Cis-elements and trans-factors that regulate expression of the maize Cat1 antioxidant gene in response to ABA and osmotic stress: H2O2 is the likely intermediary signaling molecule for the response.The Plant journal : for cell and molecular biology, 22 2
L. Mira, L. Maia, L. Barreira, C.F. Manso (1995)
Evidence for free radical generation due to NADH oxidation by aldehyde oxidase during ethanol metabolismJ. Phytopathol., 318
Bandurski (1995)
10.1007/978-94-011-0473-9_3
U. Branzoli, V. Massey (1974)
Preparation of aldehyde oxidase in its native and deflavo forms. Comparison of spectroscopic and catalytic properties.The Journal of biological chemistry, 249 14
R.T. Omarov, S. Akaba, T. Koshiba, S.H. Lips (1999)
Aldehyde oxidase in roots, leaves and seeds of barley (Hordeum vulgare L.)J. Biol. Chem., 50
H. Sekimoto, M. Seo, N. Dohmae, K. Takio, Y. Kamiya, T. Koshiba (1997)
Cloning and Molecular Characterization of Plant Aldehyde Oxidase*The Journal of Biological Chemistry, 272
S. Sanders, R. Eisenthal, R. Harrison (1997)
NADH oxidase activity of human xanthine oxidoreductase--generation of superoxide anion.European journal of biochemistry, 245 3
M. Sagi, R. Fluhr, S. Lips (1999)
Aldehyde oxidase and xanthine dehydrogenase in a flacca tomato mutant with deficient abscisic acid and wilty phenotypePlant physiology, 120 2
M. Leydecker, T. Moureaux, Y. Kraepiel, K. Schnorr, M. Caboche (1995)
Molybdenum Cofactor Mutants, Specifically Impaired in Xanthine Dehydrogenase Activity and Abscisic Acid Biosynthesis, Simultaneously Overexpress Nitrate Reductase, 107
C. Hesberg, R. Hänsch, R. Mendel, F. Bittner (2004)
Tandem Orientation of Duplicated Xanthine Dehydrogenase Genes from Arabidopsis thalianaJournal of Biological Chemistry, 279
L. Xiong, K. Schumaker, Jian‐Kang Zhu (2002)
Cell Signaling during Cold, Drought, and Salt Stress Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.000596.The Plant Cell Online, 14
R. Mertens, B. Deus-Neumann, E. Weiler (1983)
Monoclonal antibodies for the detection and quantitation of the endogenous plant growth regulator, abscisic acidFEBS Letters, 160
J. Kwak, I. Mori, Z. Pei, N. Leonhardt, M. Torres, J. Dangl, Rachel Bloom, S. Bodde, Jonathan Jones, J. Schroeder (2003)
NADPH oxidase AtrbohD and AtrbohF genes function in ROS‐dependent ABA signaling in ArabidopsisThe EMBO Journal, 22
R. Mendel, R. Hänsch (2002)
Molybdoenzymes and molybdenum cofactor in plants.Journal of experimental botany, 53 375
M. Seo, H. Koiwai, S. Akaba, T. Komano, T. Oritani, Y. Kamiya, T. Koshiba (2000a)
Abscisic aldehyde oxidase in leaves of Arabidopsis thalianaPlant Physiol., 23
L. Xiong, K.S. Schumaker, J.K. Zhu (2002a)
Cell signaling during cold, drought, and salt stressPlant Physiol., 14
S. Clough, A. Bent (1998)
Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana.The Plant journal : for cell and molecular biology, 16 6
M. Sagi, R. Fluhr (2001)
Superoxide production by plant homologues of the gp91(phox) NADPH oxidase. Modulation of activity by calcium and by tobacco mosaic virus infection.Plant physiology, 126 3
R.R. Mendel, A. Muller (1976)
A common genetic determination of xanthine dehydrogenase and NR in N. tabacumBiochem. Biophys. Acta, 170
K. Shinozaki, Yamaguchi-Shinozaki Kazuko (1997)
Gene Expression and Signal Transduction in Water-Stress Response, 115
C. Harris, V. Massey (1997)
The Oxidative Half-reaction of Xanthine Dehydrogenase with NAD; Reaction Kinetics and Steady-state Mechanism*The Journal of Biological Chemistry, 272
R. Omarov, S. Akaba, T. Koshiba, S. Lips (1999)
Aldehyde oxidase in roots, leaves and seeds of barley (Hordeum vulgare L.)Journal of Experimental Botany, 50
M. Sagi, O. Davydov, S. Orazova, Z. Yesbergenova, R. Ophir, J. W. Stratmann, R. Fluhr (2004)
Plant respiratory burst oxidase homologs impinges on wound responsiveness and development in Lycopersicon esculentumPlanta, 16
X. Min, K. Okada, B. Brockmann, T. Koshiba, Y. Kamiya (2000)
Molecular cloning and expression patterns of three putative functional aldehyde oxidase genes and isolation of two aldehyde oxidase pseudogenes in tomatoJ. Biol. Chem., 1493
K. Rajagopalan, P. Handler (1964)
HEPATIC ALDEHYDE OXIDASE. II. DIFFERENTIAL INHIBITION OF ELECTRON TRANSFER TO VARIOUS ELECTRON ACCEPTORS.The Journal of biological chemistry, 239
M. Deng, T. Moureaux, M. Caboche (1989)
Tungstate, a molybdate analog inactivating nitrate reductase, deregulates the expression of the nitrate reductase structural geneJ. Biol. Chem., 91
Mingyi Jiang, Jianhua Zhang (2002)
Water stress-induced abscisic acid accumulation triggers the increased generation of reactive oxygen species and up-regulates the activities of antioxidant enzymes in maize leaves.Journal of experimental botany, 53 379
R. Mendel, A. Müller (1976)
A Common Genetic Determinant of Xanthine Dehydrogenase and Nitrate Reductase in Nicotiana tabacumBiochemie und Physiologie der Pflanzen, 170
I.B. Taylor (1991)
Abscisic Acid, Physiology and BiochemistryPlant Cell
R. Omarov, D. Dräger, R. Tischner, H. Lips (2003)
Aldehyde oxidase isoforms and subunit composition in roots of barley as affected by ammonium and nitrate.Physiologia plantarum, 117 3
T. Eilers, G. Schwarz, H. Brinkmann, C. Witt, T. Richter, J. Nieder, B. Koch, R. Hille, R. Hänsch, R. Mendel (2001)
Identification and biochemical characterization of Arabidopsis thaliana sulfite oxidase. A new player in plant sulfur metabolism.The Journal of biological chemistry, 276 50
Hiroyuki Sekimoto, M. Seo, Naoto Kawakami, T. Komano, Sophie Desloire, S. Liotenberg, A. Marion-Poll, M. Caboche, Yuji Kamiya, T. Koshiba (1998)
Molecular cloning and characterization of aldehyde oxidases in Arabidopsis thaliana.Plant & cell physiology, 39 4
L. Mira, L. Maia, L. Barreira, C. Manso (1995)
Evidence for free radical generation due to NADH oxidation by aldehyde oxidase during ethanol metabolism.Archives of biochemistry and biophysics, 318 1
R. Omarov, D. Dräger, R. Tischner, H. Lips (2003)
Aldehyde oxidase isoforms and subunit composition in roots of barley as affected by ammonium and nitratePlant Physiol., 117
Z. Pei, Y. Murata, G. Benning, S. Thomine, Birgit Klüsener, G. Allen, E. Grill, J. Schroeder (2000)
Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cellsNature, 406
H. Bohnert, R. Jensen (1996)
Strategies for engineering water-stress tolerance in plantsTrends in Biotechnology, 14
Omarov (1999)
10.1093/jexbot/50.330.63J. Exp. Bot., 50
R.M. Wright, D.A. Clayton, M.G. Riley, J.L. McManaman, J.E. Repine (1999)
cDNA cloning, sequencing, and characterization of male and female rat liver aldehyde oxidase (rAOX1): differences in redox status may distinguish male and female forms of hepatic AOXJ. Biol. Chem., 274
R.R. Mendel, R. Hänsch (2002)
Molybdoenzymes and molybdenum cofactor in plantsFEBS Lett., 53
R. Harrison (2002)
Structure and function of xanthine oxidoreductase: where are we nowAnnu. Rev. Plant Mol. Plant Physiol., 33
H. Hansen, K. Grossmann (2000)
Auxin‐induced ethylene triggers abscisic acid biosynthesis and growth inhibitionJ. Biol. Chem., 124
M. Walker-Simmons, David Kudrna (1989)
Reduced Accumulation of ABA during Water Stress in a Molybdenum Cofactor Mutant of Barley.Plant physiology, 90 2
J. Alonso, A. Stepanova, Thomas Leisse, Christopher Kim, Huaming Chen, P. Shinn, Denise Stevenson, J. Zimmerman, Pascual Barajas, Rosa Cheuk, Carmelita Gadrinab, Collen Heller, Albert Jeske, Eric Koesema, Cristina Meyers, Holly Parker, Lance Prednis, Yasser Ansari, Nathan Choy, Hashim Deen, M. Geralt, N. Hazari, Emily Hom, Meagan Karnes, C. Mulholland, Ral Ndubaku, Ian Schmidt, P. Guzmán, Laura Aguilar-Henonin, M. Schmid, D. Weigel, D. Carter, T. Marchand, E. Risseeuw, Debra Brogden, Albana Zeko, W. Crosby, C. Berry, J. Ecker (2003)
Genome-Wide Insertional Mutagenesis of Arabidopsis thalianaScience, 301
M. Sagi, R. Fluhr, S.H. Lips (1999)
Aldehyde oxidase and xanthine dehydrogenase in a flacca tomato mutant with deficient abscisic acid and wilty phenotypePlant Cell, 120
T. Koshiba, Eriko Saito, Naoki, Naoki Yamamoto, Mitsuhiko SatÔ (1996)
Purification and Properties of Flavin- and Molybdenum-Containing Aldehyde Oxidase from Coleoptiles of Maize, 110
Mendel (2002)
10.1093/jxb/erf038J. Exp. Bot., 53
F. Bittner, M. Oreb, R. Mendel (2001)
ABA3 Is a Molybdenum Cofactor Sulfurase Required for Activation of Aldehyde Oxidase and Xanthine Dehydrogenase in Arabidopsis thaliana *The Journal of Biological Chemistry, 276
S. Chakraborty, V. Massey (2002)
Reaction of reduced flavins and flavoproteins with diphenyliodonium chloridePlant J., 277
K.V. Rajagopalan, J.L. Johnson (1992)
The pterin molybdenum cofactorPlant Physiol., 267
K.V. Rajagopalan, P. Handler (1964)
Hepatic aldehyde oxidase. II Differential inhibition of electron transfer to various electron acceptorsPlant Cell Physiol., 239
G. Rothe (1974)
Aldehyde oxidase isoenzymes (E.C. 1.2.3.1) in potato tubers (Solanum tuberosum)Plant and Cell Physiology, 15
J. Joo, Y. Bae, June-Seung Lee (2001)
Role of auxin-induced reactive oxygen species in root gravitropism.Plant physiology, 126 3
Zhao Z. (2001)
Interaction between reactive oxygen species and nitric oxide in drought‐induced abscisic acid synthesis in root tips of wheat seedlingsAust. J. Plant Physiol., 28
Mingyi Jiang, Jianhua Zhang (2002)
Involvement of plasma-membrane NADPH oxidase in abscisic acid- and water stress-induced antioxidant defense in leaves of maize seedlingsPlanta, 215
P. Fossati, L. Prencipe, G. Berti (1980)
Use of 3,5-dichloro-2-hydroxybenzenesulfonic acid/4-aminophenazone chromogenic system in direct enzymic assay of uric acid in serum and urine.Clinical chemistry, 26 2
E. Lopez‐Huertas, J.F. Corpas, M.L. Sandalio, A.L. Rio (1999)
Characterization of membrane polypeptides from pea leaf peroxisomes involved in superoxide radical generationFEBS Lett., 337
T. Hawkes, R. Bray (1984)
Quantitative transfer of the molybdenum cofactor from xanthine oxidase and from sulphite oxidase to the deficient enzyme of the nit-1 mutant of Neurospora crassa to yield active nitrate reductase.The Biochemical journal, 219 2
M. Sagi, R. Omarov, S. Lips (1998)
The Mo-hydroxylases xanthine dehydrogenase and aldehyde oxidase in ryegrass as affected by nitrogen and salinityPlant Science, 135
S.A. Sanders, R. Eisenthal, R. Harrison (1997)
NADH oxidase activity of human xanthine oxidoreductase – generation of superoxide anionPlant Physiol., 245
R.J. Mertens, B. Deus‐Neumann, E.W. Weiler (1985)
Monoclonal antibodies for the detection and quantification of the endogenous plant growth regulator, abscisic acidArch. Biochem. Biophys., 160
K. Rajagopalan, Jean Johnson (1992)
The pterin molybdenum cofactors.The Journal of biological chemistry, 267 15
J. Nguyen (1986)
Plant xanthine dehydrogenase: its distribution, properties and function, 24
R. Omarov, M. Sagi, S.H. Lips (1998)
Regulation of aldehyde oxidase and nitrate reductase in roots of barley (Hordeum vulgare L.) by nitrogen sources and salinityPhysiol. Plant., 49
S. Neill, R. Desikan, J. Hancock (2002)
Hydrogen peroxide signallingJ. Exp. Bot., 5
G. Rothe (1974)
Aldehyde oxidase isoenzymes (E.C. 1. 2. 3.1) in potato tubers (Solanum tuberosum)Plant Sci., 15
M. Sagi, R.T. Omarov, S.H. Lips (1998)
The Mo‐hydroxylases xanthine dehydrogenase and aldehyde oxidase in ryegrass as affected by nitrogen and salinityPlant J., 135
A. Glatigny, C. Scazzocchio (1995)
Cloning and Molecular Characterization of hxA, the Gene Coding for the Xanthine Dehydrogenase (Purine Hydroxylase I) of Aspergillus nidulans(*)The Journal of Biological Chemistry, 270
U. Laemmli (1970)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 227
T. Eilers, G. Schwarz, H. Brinkmann, C. Witt, T. Richter, J. Niede, B. Koch, R. Hille, R. Hänsch, R.R. Mendel (2001)
Identification and biochemical characterization of Arabidopsis thaliana sulfite oxidase: a new player in plant sulfur metabolismPlant Physiol., 276
P. Montalbini (1992)
Ureides and enzymes of ureide synthesis in wheat seeds and leaves and effect of allopurinol on Puccinia recondita f. sp. tritici infectionPlant Science, 87
C. Hesberg, R. Hänsch, R.R. Mendel, F. Bittner (2004)
Tandem orientation of duplicated xanthine dehydrogenase genes from Arabidopsis thaliana: differential gene expression and enzyme activitiesChem. Rev., 279
E. López-Huertas, F. Corpas, L. Sandalio, L. Río (1999)
Characterization of membrane polypeptides from pea leaf peroxisomes involved in superoxide radical generation.The Biochemical journal, 337 ( Pt 3)
The plant molybdenum‐cofactor (Moco) and flavin‐containing enzymes, xanthine dehydrogenase (XDH; EC 1.2.1.37) and aldehyde oxidase (AO; EC 1.2.3.1) are thought to play important metabolic roles in purine metabolism and hormone biosynthesis, respectively. Their animal counterparts contribute to reactive oxygen species (ROS) production in numerous pathologies and here we examined these enzymes as potential sources of ROS in plants. Novel in‐gel assay techniques and Moco sulfurase mutants, lacking a sulfur ligand in their Moco active center, were employed to demonstrate that the native tomato and Arabidopsis XDHs are capable of producing O, but not H2O2, while the animal counterpart was shown to produce both, O and H2O2. Superoxide production was dependent on Moco sulfuration when using hypoxanthine/xanthine but not NADH as substrates. The activity was inhibited by diphenylene iodonium (DPI), a suicide inhibitor of FAD containing enzymes. Analysis of XDH in an Arabidopsis Atxdh1 T‐DNA insertion mutant and RNA interference lines revealed loss of O activity, providing direct molecular evidence that plant XDH generates superoxides. Contrary to XDH, AO activity produced only H2O2 dissimilar to native animal AO, that can produce O as well. Surprisingly, H2O2 accumulation was not sensitive to DPI. Plant ROS production and transcript levels of AO and XDH were rapidly upregulated by application of abscisic acid and in water‐stressed leaves and roots. These results, supported by in vivo measurement of ROS accumulation, indicate that plant AO and XDH are possible novel sources for ROS increase during water stress.
The Plant Journal – Wiley
Published: Jun 1, 2005
Keywords: ; ; ; ; ;
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.