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Biomass Estimation in Plant Cell Cultures: A Neural Network Approach

Biomass Estimation in Plant Cell Cultures: A Neural Network Approach 10.1002/btpr.5420110112.abs The special characteristics of plant cell cultures make it difficult to use conventional analytical techniques for on‐line biomass monitoring. Meanwhile, promising results have been obtained using mathematical models and recursive estimation algorithms. However, in this case, additional experimental effort is necessary to obtain a reasonable description of the process. Recently, techniques using more empirical approaches have been proposed to describe complex processes, minimizing the experimental work needed for their application. In this paper, we report on the use of artificial neural networks to monitor biomass evolution in plant cell cultures. The results obtained with a three‐layered network are presented. Method requirements and capabilities are compared with the method based on the extended Kalman filter used in previous work. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Biotechnology Progress Wiley

Biomass Estimation in Plant Cell Cultures: A Neural Network Approach

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References (21)

Publisher
Wiley
Copyright
Copyright © 1995 American Institute of Chemical Engineers (AIChE)
ISSN
8756-7938
eISSN
1520-6033
DOI
10.1021/bp00031a012
Publisher site
See Article on Publisher Site

Abstract

10.1002/btpr.5420110112.abs The special characteristics of plant cell cultures make it difficult to use conventional analytical techniques for on‐line biomass monitoring. Meanwhile, promising results have been obtained using mathematical models and recursive estimation algorithms. However, in this case, additional experimental effort is necessary to obtain a reasonable description of the process. Recently, techniques using more empirical approaches have been proposed to describe complex processes, minimizing the experimental work needed for their application. In this paper, we report on the use of artificial neural networks to monitor biomass evolution in plant cell cultures. The results obtained with a three‐layered network are presented. Method requirements and capabilities are compared with the method based on the extended Kalman filter used in previous work.

Journal

Biotechnology ProgressWiley

Published: Jan 1, 1995

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