Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/specific-role-for-the-ph-domain-of-dynamin-1-in-the-regulation-of-cWoIIX80x2
References (76)
-
C. Artalejo, John HENLEYt, Mark MCNIVENt, H. PALFREYt (1995)
Rapid endocytosis coupled to exocytosis in adrenal chromaffin cells involves Ca2+, GTP, and dynamin but not clathrin.Proceedings of the National Academy of Sciences of the United States of America, 92 18
-
T. Baba, H. Damke, J. Hinshaw, K. Ikeda, S. Schmid, D. Warnock (1995)
Role of dynamin in clathrin-coated vesicle formation.Cold Spring Harbor symposia on quantitative biology, 60
-
K. Ferguson, M. Lemmon, J. Schlessinger, P. Sigler (1995)
Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domainCell, 83
-
(1994)
Structure of the pleckstrin homology domain Ca 2 , GTP and dynamin but not clathrin -
P. Robinson, Jun-Ping Liu, K. Powell, E. Fykse, T. Südhof (1994)
Phosphorylation of dynamin I and synaptic-vesicle recyclingTrends in Neurosciences, 17
-
Yi Zheng, D. Zangrilli, R. Cerione, A. Eva (1996)
The Pleckstrin Homology Domain Mediates Transformation by Oncogenic Dbl through Specific Intracellular Targeting*The Journal of Biological Chemistry, 271
-
T. Kosaka, K. Ikeda (1983)
Reversible blockage of membrane retrieval and endocytosis in the garland cell of the temperature-sensitive mutant of Drosophila melanogaster, shibirets1The Journal of Cell Biology, 97
-
I. Gout, R. Dhand, I. Hiles, M. Fry, G. Panayotou, P. Das, O. Truong, N. Totty, J. Hsuan, G. Booker, I. Campbell, M. Waterfield (1993)
The GTPase dynamin binds to and is activated by a subset of SH3 domainsCell, 75
-
R. Obar, C. Collins, J. Hammarback, H. Shpetner, R. Vallee (1990)
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteinsNature, 347
-
(1996)
Fast steps in exocytosis and PCR products derived from cDNA clones specific for dynamins-1 or -2. endocytosis studied by capacitance methods in endocrine cells -
Pilar Garcia, Rakesh Gupta, Shefali Shah, A. Morris, S. Rudge, S. Scarlata, Victoria Petrova, Stuart McLaughlin, M. Rebecchi (1995)
The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes.Biochemistry, 34 49
-
M. Lemmon, K. Ferguson, R. O'brien, P. Sigler, J. Schlessinger (1995)
Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.Proceedings of the National Academy of Sciences of the United States of America, 92 23
-
K. Ferguson, M. Lemmon, P. Sigler, J. Schlessinger (1995)
Scratching the surface with the PH domainNature Structural Biology, 2
-
K. Ferguson, M. Lemmon, J. Schlessinger, P. Sigler (1994)
Crystal structure at 2.2 Å resolution of the pleckstrin homology domain from human dynaminCell, 79
-
(1994)
Calciummutant dynamin specifically blocks endocytic vesicle formation -
H. Gersdorff, Gary Mathews (1994)
Dynamics of synaptic vesicle fusion and membrane retrieval in synaptic terminalsNature, 367
-
(1991)
Ribbons 2 . 0 . J . Appl . Crystallogr . , 24 , 958 – 961 . signalling -
Linda McCollam, L. Bonfini, C. Karlovich, B. Conway, Lynn Kozma, U. Banerjee, M. Czech (1995)
Functional Roles for the Pleckstrin and Dbl Homology Regions in the Ras Exchange Factor Son-of-sevenless (*)The Journal of Biological Chemistry, 270
-
M. Lemmon, K. Ferguson, J. Schlessinger (1996)
PH Domains: Diverse Sequences with a Common Fold Recruit Signaling Molecules to the Cell SurfaceCell, 85
-
D. Timm, K. Salim, I. Gout, L. Guruprasad, M. Waterfield, T. Blundell (1994)
Crystal structure of the pleckstrin homology domain from dynaminNature Structural Biology, 1
-
(1996)
A role Powell,K.A. and Robinson,P.J -
(1995)
The pleckstrinformation -
Jie Zheng, S. Cahill, M. Lemmon, D. Fushman, J. Schlessinger, D. Cowburn (1996)
Identification of the binding site for acidic phospholipids on the pH domain of dynamin: implications for stimulation of GTPase activity.Journal of molecular biology, 255 1
-
(1995)
LX, 235-242. homology domain in insulin receptor substrate-1 sensitizes insulin Carson,M. (1991) Ribbons 2.0 -
(1993)
Effects incubation of hybridized blots with 5 μg/ml RNase A in 2ϫ SSC for of mutant rat dynamin on endocytosis -
A. Henkel, W. Almers (1996)
Fast steps in exocytosis and endocytosis studied by capacitance measurements in endocrine cellsCurrent Opinion in Neurobiology, 6
-
Matti Saraste, Marko Hyvönen (1995)
Pleckstrin homology domains: a fact file.Current opinion in structural biology, 5 3
-
(1995)
Functional roles for the pleckstrin divalent cation receptor for rapid endocytosis , but not exocytosis , in and Dbl homology regions in the Ras exchange factor Son - of - adrenal chromaffin cells -
H. Damke, T. Baba, D. Warnock, S. Schmid (1994)
Induction of mutant dynamin specifically blocks endocytic coated vesicle formationThe Journal of Cell Biology, 127
-
M. Macias, A. Musacchio, H. Ponstingl, M. Nilges, M. Saraste, H. Oschkinat (1994)
Structure of the pleckstrin homology domain from β-spectrinNature, 369
-
(1995)
The pleckstrin -
(1995)
Rapid Macias,M.J., Musacchio,A., Ponstingl,H., Nilges,M., Saraste,M. and endocytosis coupled to exocytosis in adrenal chromaffin cells -
M. Carson (1991)
RIBBONS 2.0Journal of Applied Crystallography, 24
-
(1993)
min prior to high-stringency rinses (0.1ϫ SSC/0.1% SDS; 4ϫ for -
M. Myers, T. Grammer, Jennifer Brooks, Erin Glasheen, Ling-mei Wang, X. Sun, J. Blenis, J. Pierce, M. White (1995)
The Pleckstrin Homology Domain in Insulin Receptor Substrate-1 Sensitizes Insulin Signaling (*)The Journal of Biological Chemistry, 270
-
M. Cifuentes, L. Honkanen, M. Rebecchi (1993)
Proteolytic fragments of phosphoinositide-specific phospholipase C-delta 1. Catalytic and membrane binding properties.The Journal of biological chemistry, 268 16
-
ME Cifuentes, L Honkanen, MJ Rebecchi (1993)
Proteolytic fragments of phosphoinositide‐specific PLCδ1. Catalytic and membrane‐binding propertiesJ Biol Chem, 268
-
R. Vallee, P. Okamoto (1995)
The regulation of endocytosis: identifying dynamin's binding partners.Trends in cell biology, 5 2
-
J. Herskovits, H. Shpetner, C. Burgess, R. Vallee (1993)
Microtubules and Src homology 3 domains stimulate the dynamin GTPase via its C-terminal domain.Proceedings of the National Academy of Sciences of the United States of America, 90 24
-
(1995)
PH domains : a fact file -
Y. Noda, T. Nakata, N. Hirokawa (1993)
Localization of dynamin: Widespread distribution in mature neurons and association with membranous organellesNeuroscience, 55
-
J. Harlan, P. Hajduk, H. Yoon, S. Fesik (1994)
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphateNature, 371
-
J. Sontag, E. Fykse, Yuri Ushkaryov, Jun-Ping Liu, Phillip Robinson, Thomas Südhof (1994)
Differential expression and regulation of multiple dynamins.The Journal of biological chemistry, 269 6
-
T. Nakata, R. Takemura, N. Hirokawa (1993)
A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis.Journal of cell science, 105 ( Pt 1)
-
Robin Scaife, R. Margolis (1990)
Biochemical and immunochemical analysis of rat brain dynamin interaction with microtubules and organelles in vivo and in vitroThe Journal of Cell Biology, 111
-
R. Scaife, I. Gout, M. Waterfield, R. Margolis (1994)
Growth factor‐induced binding of dynamin to signal transduction proteins involves sorting to distinct and separate proline‐rich dynamin sequences.The EMBO Journal, 13
-
(1991)
Multiple forms of dynamin -
(1993)
Localization of dynamin -
H. Yoon, P. Hajduk, A. Petros, E. Olejniczak, R. Meadows, S. Fesik (1994)
Solution structure of a pleckstrin-homology domainNature, 369
-
M. Vihinen, M. Zvelebil, Qili Zhu, R. Brooimans, H. Ochs, B. Zegers, L. Nilsson, M. Waterfield, C. Smith (1995)
Structural basis for pleckstrin homology domain mutations in X-linked agammaglobulinemia.Biochemistry, 34 5
-
(1994)
Identification of Vallee,R.B -
1% agarose/1.2% formaldehyde gels then transferred to nylon mem-Nature -
Toby Gibson, Marko Hyvönen, Andrea Musacchio, Matti Saraste, E. Birney (1994)
PH domain: the first anniversary.Trends in biochemical sciences, 19 9
-
H. Shpetner, R. Vallee (1992)
Dynamin is a GTPase stimulated to high levels of activity by microtubulesNature, 355
-
Ming-Ming Zhou, K. Ravichandran, E. Olejniczak, A. Petros, R. Meadows, M. Sattler, J. Harlan, W. Wade, S. Burakoff, S. Fesik (1995)
Structure and ligand recognition of the phosphotyrosine binding domain of ShcNature, 378
-
Kate Powell, Phillip Robinson (1995)
Dephosphin/dynamin is a neuronal phosphoprotein concentrated in nerve terminals: Evidence from rat cerebellumNeuroscience, 64
-
T. Cook, R. Urrutia, M. McNiven (1994)
Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues.Proceedings of the National Academy of Sciences of the United States of America, 91
-
AW Henkel, W Almers (1996)
Fast steps in exocytosis and endocytosis studied by capacitance methods in endocrine cellsCurr Opin Neurobiol, 6
-
M. Hyvönen, M. Macias, M. Nilges, H. Oschkinat, M. Saraste, M. Wilmanns (1995)
Structure of the binding site for inositol phosphates in a PH domain.The EMBO Journal, 14
-
T. Parsons, D. Lenzi, W. Almers, W. Roberts (1994)
Calcium-triggered exocytosis and endocytosis in an isolated presynaptic cell: Capacitance measurements in saccular hair cellsNeuron, 13
-
(1994)
Binding of G protein βγ-subunits to pleckstrin homology domains -
(1993)
A novel member -
(1995)
Functional roles for the pleckstrin divalent cation receptor for rapid endocytosis, but not exocytosis -
(1996)
PH domains : diverse sequences with a common fold recruit signalling molecules References to the cell surface -
Carol David, Peter McPherson, O. Mundigl, P. Camilli (1996)
A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.Proceedings of the National Academy of Sciences of the United States of America, 93 1
-
A. Bliek, T. Redelmeier, H. Damke, E. Tisdale, E. Meyerowitz, S. Schmid, S. Schmid (1993)
Mutations in human dynamin block an intermediate stage in coated vesicle formationThe Journal of Cell Biology, 122
-
D. Fushman, S. Cahill, M. Lemmon, J. Schlessinger, D. Cowburn (1995)
Solution structure of pleckstrin homology domain of dynamin by heteronuclear NMR spectroscopy.Proceedings of the National Academy of Sciences of the United States of America, 92 3
-
J. Herskovits, C. Burgess, R. Obar, R. Vallee (1993)
Effects of mutant rat dynamin on endocytosisThe Journal of Cell Biology, 122
-
(1991)
Multiple forms of dynamin the dynamin family of GTP - binding proteins is expressed specificallyare encoded by shibire , a Drosophila gene involved in endocytosis . in the testis -
A. Bliek, Elliot Meyerowrtz (1991)
Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular trafficNature, 351
-
P. Tuma, C. Collins (1995)
Dynamin Forms Polymeric Complexes in the Presence of Lipid VesiclesThe Journal of Biological Chemistry, 270
-
K. Touhara, James Inglese, J. Pitcher, G. Shaw, R. Lefkowitz (1994)
Binding of G protein beta gamma-subunits to pleckstrin homology domains.The Journal of biological chemistry, 269 14
-
C. Artalejo, A. Elhamdani, H. Palfrey (1996)
Calmodulin Is the Divalent Cation Receptor for Rapid Endocytosis, but Not Exocytosis, in Adrenal Chromaffin CellsNeuron, 16
-
Paul Thomas, Albert Lee, J. Wong, Wolfhard Almers (1994)
A triggered mechanism retrieves membrane in seconds after Ca(2+)- stimulated exocytosis in single pituitary cellsThe Journal of Cell Biology, 124
-
(1993)
The GTPase dynamin binds to and is activated by dideoxynucleotide technique. For RNA hybridization analysis, total RNA a subset of SH3 domains -
M. Chen, R. Obar, C. Schroeder, T. Austin, C. Poodry, S. Wadsworth, R. Vallee (1991)
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosisNature, 351
- Publisher
- Wiley
- Copyright
- Copyright © 2013 Wiley Periodicals, Inc
- ISSN
- 0261-4189
- eISSN
- 1460-2075
- DOI
- 10.1093/emboj/16.7.1565
- pmid
- 9130701
- Publisher site
- See Article on Publisher Site
Abstract
Dynamin plays a key role in the scission event common to various types of endocytosis. We demonstrate that the pleckstrin homology (PH) domain of dynamin‐1 is critical in the process of rapid endocytosis (RE) in chromaffin cells. Introduction of this isolated PH domain into cells at concentrations as low as 1 μM completely suppressed RE. PH domains from other proteins, including that from the closely related dynamin‐2, were ineffective as inhibitors, even at high concentrations. Mutational studies indicated that a pair of isoform‐specific amino acids, located in a variable loop between the first two β‐strands, accounted for the differential effect of the two dynamin PH domains. Switching these amino acids in the dynamin‐2 PH domain to the equivalent residues in dynamin‐1 (SL→GI) generated a molecule that blocked RE. Thus, the PH domain of dynamin‐1 is essential for RE and exhibits a precise molecular selectivity. As chromaffin cells express both dynamin‐1 and ‐2, we speculate that different isoforms of dynamin may regulate distinct endocytotic processes and that the PH domain contributes to this specificity.
Journal
The EMBO Journal – Wiley
Published: Jan 1, 1997
Keywords: ; ; ;