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J. Owen, F. Better, J. Hoban (1960)
A SIMPLE METHOD FOR THE DETERMINATION OF SERUM HAPTOGLOBINSJournal of Clinical Pathology, 13
T h e direct diazo reaction of bile pigments in eeruni
Noyes Noyes, Bothwell Bothwell, Finch Finch (1960)
The role of the reticulo‐endothelial cell in iron metabolismBrit. J. Haeinat., C
Lohr Lohr, Waller Waller (1961)
Biochemie und Pathogenese der enzymopenischen hämo‐lytischen Anämien.Deutsch. Med. Wschr., 86
(1961)
Die Wirkung von Nuclrosiden und Steroiden auf die mechanische Resistenz frischer und gelagerter Erythroq tcn
(1962)
Bergmeyer: Glutathion
H. Bock, hämolytischen Anämien, Von Löhr, H. Wailer (1961)
Biochemie und Pathogenese der enzymopenischen hämolytischen Anämien1, 2Deutsche Medizinische Wochenschrift, 86
Nosslin Nosslin (1960)
The direct diazo reaction of bile pigments in serum.Scand. J. Clin. Lab. Invest., 12
Simon Simon, Chapman Chapman, Finch Finch (1962)
Adenine in red cell preservation.J. Clin. Invest., 41
E. Simon (1962)
Red cell preservation: further studies with adenine.Blood, 20
B. Lowy, M. Williams, I. London (1962)
Enzymatic deficiencies of purine nucleotide synthesis in the human erythrocyte.The Journal of biological chemistry, 237
(1962)
Adenosin - 5 ' - triphosphat und Aden - osin - 5 ' - diphosphat uncl Adenosin - 5 ' - monophos - phat
(1962)
Glucose metabolism in normal erythrocytes . 11 . Kinetics of the hexokinase reaction in hemolysates Das Verhalten von Enzymen und Substraten hei der Konservier - ung von Blut in verschiedenen Medien
K. Nakao, T. Wada, T. Kamiyama, M. Nakao, K. Nagano (1962)
A Direct Relationship between Adenosine Triphosphate-level and in vivo Viability of ErythrocytesNature, 194
P. Mollison (1961)
Further observations on the normal survival curve of 51 Cr-labelled red cells.Clinical science, 21
T. Wada, F. Takaku, K. Nakao, M. Nakao, T. Nakao, H. Yoshikawa (1960)
Posttransfusion Survival of the Red Blood Cells Stored in a Medium Containing Adenine and Inosine, 36
C. Verdier, J. Killander (1962)
Storage of Human Red Blood CellsActa Physiologica Scandinavica, 54
(1962)
Untersuchung zur verbesserten Zellkonservierung. I. Ober den Einfluss von Purinnucleosiden auf den Erythrocy~ei~stotfwechsel
L. Garby, M. Hjelm (1962)
Short-term assessment of red cell survival with an improved cr51-technique.Scandinavian journal of clinical and laboratory investigation, 14
H. Bowman (1963)
Red Cell Preservation in Citrate‐Phosphate‐Dextrose and in Acid‐Citrate‐DextroseTransfusion, 3
M. Nakao, T. Nakao, M. Tatibana, H. Yoshikawa (1960)
PHOSPHORUS METABOLISM IN HUMAN ERYTHROCYTE III. REGENERATION OF ADENOSINE TRIPHOSPHATE IN LONG-STORED ERYTHROCYTE BY INCUBATION WITH INOSINE AND ADENINEJournal of Biochemistry, 47
C. Deverdier, C. Hoegman, L. Garby, J. Killander (1964)
STORAGE OF HUMAN RED BLOOD CELLS. II. THE EFFECT OF PH AND OF THE ADDITION OF ADENINE.Acta physiologica Scandinavica, 60
(1962)
Das Verhalten von Enzymen und Substraten hei der Konservierung von Blut in verschiedenen Medien
E. Simon, R. Chapman, C. Finch (1962)
ADENINE IN RED CELL PRESERVATION.Bibliotheca haematologica, 19
Loehr Gw, Waller Hd (1961)
The biochemistry and pathogenesis of enzymopenic hemolytic anemiasDeutsche Medizinische Wochenschrift, 86
Wosegien Wosegien, Dose Dose, Fischer Fischer (1962)
Untersuchung zur verbesserten Zellkonservierung. I. t)ber den Einfluss von Purinnucleosiden auf den Erythrocytenstotfwechsel. Trennung saureloslicher Phosphate und erste Erge‐bnisse.Klin. Wschr., 40
Pathogenese enzymopenisdien, hämolytischen Anämien, Von Löhr (1961)
Biochemie und Pathogenese der enzymopenischen hämolytischen Anämien1Deutsche Medizinische Wochenschrift, 86
Grignani Grignani, Löhr Löhr (1960)
Über die Hexokinase in menschlichen Blutzellen.Klin. Wschr., 38
(1960)
Ober die Hexokinase in menschlichen
W. Noyes, T. Bothwell, C. Finch (1960)
The Role of the Reticulo‐Endothelial Cell in Iron Metabolism *British Journal of Haematology, 6
M. Nakao, T. Nakao, M. Tatibana, H. Yoshikawa, T. Abe (1959)
Effect of inosine and adenine on adenosine triphosphate regeneration and shape transformation in long-stored erythrocyts.Biochimica et biophysica acta, 32
Shirley Crouch, C. Bishop (1963)
The Maintenance of ATP in Stored Blood by Adenosine and InosineTransfusion, 3
C. Verdier, J. Killander (1962)
Storage of human red blood cells. I. The effect of ACD solution on breakdown of glucose.Acta physiologica Scandinavica, 54
Posttransfusion viability was studied in red blood cells stored for 21 days in ACD solution and for 35 days in ACD solution supplemented with adenine to a final concentration of 0.5 mM. The survival of radio‐chromium‐labeled red cells was determined after transfusion of 10 ml. of autologous blood and 350–400 ml. homologous blood. The viability values were about the same for the two transfusion procedures. The mean posttransfusion viability was 80 per cent for erythrocytes stored for 35 days in the medium containing adenine and 79 per cent for cells preserved in ACD solution for 21 days. The concentration in the erythrocytes of ATP, ADP, AMP, reduced and oxidized glutathione, 2,3‐diphosphoglycerate, and four glycolytic enzymes was measured before and after storage in the two media. The ATP and the total adenine nucleotide concentrations were much higher in the red cells stored in the adenine‐containing solution. Of the enzymes tested, only phosphofructokinase decreased in activity during 35 days of storage. The decrease was about 50 per cent and was not dependent on the storage solution. This study supports the theory that decreased adenine supply is an important cause of damage to erythrocytes in ACD solution.
Transfusion – Wiley
Published: Sep 10, 1964
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