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B. Bakay (1968)
Soluble proteins of liver nuclei of rats fed 3'-methyl-4-dimethylaminoazobenzene.Biochemical pharmacology, 17 5
A. Moir, D. Eccleston (1968)
THE EFFECTS OF PRECURSOR LOADING IN THE CEREBRAL METABOLISM OF 5‐HYDROXYINDOLESJournal of Neurochemistry, 15
G. Aghajanian, J. Rosecrans, M. Sheard (1967)
Serotonin: Release in the Forebrain by Stimulation of Midbrain Raph�Science, 156
A. Coppen (1971)
Biogenic Amines and Affective Disorders
S. Adibi (1971)
Interrelationships between level of amino acids in plasma and tissues during starvation.The American journal of physiology, 221 3
R. McMenamy, J. Oncley (1958)
The specific binding of L-tryptophan to serum albumin.The Journal of biological chemistry, 233 6
E. Bliss, J. Ailion, J. Zwanziger (1968)
Metabolism of norepinephrine, serotonin and dopamine in rat brain with stress.The Journal of pharmacology and experimental therapeutics, 164 1
D. Eccleston, G. Ashcroft, T. Crawford (1965)
5‐HYDROXYINDOLE METABOLISM IN RAT BRAIN. A STUDY OF INTERMEDIATE METABOLISM USING THE TECHNIQUE OF TRYPTOPHAN LOADING—II. APPLICATIONS and DRUG STUDIESJournal of Neurochemistry, 12
J. Pérez-Cruet, A. Tagliamonte, P. Tagliamonte, G. Gessa (1972)
Changes in brain serotonin metabolism associated with fasting and satiation in ratsLife Sciences, 11
Knox We, Auerbach Vh (1955)
The hormonal control of tryptophan peroxidase in the rat.Journal of Biological Chemistry, 214
A. Green, G. Curzon (1968)
Decrease of 5-Hydroxytryptamine in the Brain provoked by Hydrocortisone and its Prevention by AllopurinolNature, 220
J. Fernstrom, R. Wurtman (1971)
Brain Serotonin Content: Physiological Dependence on Plasma Tryptophan LevelsScience, 173
A. Moir (1971)
Interaction in the cerebral metabolism of the biogenic amines: Effect of intravenous infusion of l‐tryptophan on tryptophan and tyrosine in brain and body fluidsBritish Journal of Pharmacology, 43
G. Curzon, A. Green (1969)
Effects of immobilization on rat liver tryptophan pyrrolase and brain 5‐hydroxytryptamine metabolismBritish Journal of Pharmacology, 37
U. Scapagnini, P. Preziosi, A. Schaepdryver (1969)
Influence of restraint stress, corticosterone and betamethasone on brain amine levelsPharmacological Research Communications, 1
Arthur Yuwiler, Lennart Wetterberg, Edward Geller (1971)
RELATIONSHIP BETWEEN ALTERNATE ROUTES OF TRYPTOPHAN METABOLISM FOLLOWING ADMINISTRATION OF TRYPTOPHAN PEROXIDASE INDUCERS OR STRESSORS 1Journal of Neurochemistry, 18
G. Curzon, A. Green (1970)
Rapid method for the determination of 5‐hydroxytryptamine and 5‐hydroxyindoleacetic acid in small regions of rat brainBritish Journal of Pharmacology, 39
W. Denckla, W. Denckla, H. Dewey, H. Dewey (1967)
The determination of tryptophan in plasma, liver, and urine.The Journal of laboratory and clinical medicine, 69 1
Bliss E. L. (1968)
122J. Pharmac. exp Ther., 164
J. Fernstrom, R. Wurtman (1971)
Brain Serotonin Content: Increase Following Ingestion of Carbohydrate DietScience, 174
Waalkes Tp, S. Udenfriend (1957)
A fluorometric method for the estimation of tyrosine in plasma and tissues.The Journal of laboratory and clinical medicine, 50 5
Abstract— Withdrawal of food or immobilization both led to changes in rat brain tryptophan metabolism. Brain tryptophan and 5‐hydroxyindolylacetic acid concentrations both increased while changes in 5‐hydroxytryptamine were much smaller. Changes were greater upon withdrawal of food. The brain tryptophan change did not appear merely to reflect an overall increase of brain amino acid concentrations, brain tyrosine concentration being only slightly increased by food withdrawal and significantly decreased upon immobilization. Plasma tryptophan did not increase. The changes in brain indole metabolism were not abolished by adrenalectomy. Results are discussed in relation to the regulation of brain serotonin metabolism.
Journal of Neurochemistry – Wiley
Published: Aug 1, 1972
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