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K. Westlund, R. Denney, R. Rose, C. Abell (1988)
Localization of distinct monoamine oxidase a and monoamine oxidase b cell populations in human brainstemNeuroscience, 25
W. Gibb, J. Fearnley, A. Lees (1990)
The anatomy and pigmentation of the human substantia nigra in relation to selective neuronal vulnerability.Advances in neurology, 53
G. Cohen (1983)
Catalase, Glutathione Peroxidase, Superoxide Dismutase, and Cytochrome P-450
K. Jellinger, W. Danielczyk, P. Fischer, E. Gabriel (1990)
Clinicopathological analysis of dementia disorders in the elderlyJournal of the Neurological Sciences, 95
P. Riederer, W. Rausch, B. Schmidt, P. Kruzik, C. Konradi, E. Sofić, W. Danielczyk, M. Fischer, E. Ogris (1988)
Biochemical fundamentals of Parkinson's disease.The Mount Sinai journal of medicine, New York, 55 1
M. Youdim, A. Green, M. Bloomfield, B. Mitchell, D. Heal, D. Grahame-Smith (1980)
The effects of iron deficiency on brain biogenic monoamine biochemistry and function in ratsNeuropharmacology, 19
D. German, K. Manaye, Wade Smith, D. Woodward, C. Saper (1989)
Midbrain dopaminergic cell loss in parkinson's disease: Computer visualizationAnnals of Neurology, 26
B. Drayer, W. Olanow, P. Burger, G. Johnson, R. Herfkens, S. Riederer (1986)
Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron.Radiology, 159 2
R. Uitti, A. Rajput, B. Rozdilsky, M. Bickis, T. Wollin, W. Yuen (1989)
Regional Metal Concentrations in Parkinson's Disease, Other Chronic Neurological Diseases, and Control BrainsCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 16
B. Fornstedt, A. Brun, E. Rosengren, A. Carlsson (1989)
The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigraJournal of Neural Transmission - Parkinson's Disease and Dementia Section, 1
E. Hirsch, A. Graybiel, Y. Agid (1988)
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's diseaseNature, 334
D. Dexter, C. Carter, F. Agid, Y. Agid, A. Lees, P. Jenner, C. Marsden (1986)
LIPID PEROXIDATION AS CAUSE OF NIGRAL CELL DEATH IN PARKINSON'S DISEASEThe Lancet, 328
Uitti Uitti, Rajput Rajput, Rozdilsky Rozdilsky, Bickis Bickis, Wollin Wollin, Yuen Yuen (1989)
Regional metal concentrations in Parkinson's diseases, and control brainsCan. J. Neurol. Sci., 16
P. Mcgeer, S. Itagaki, H. Akiyama, E. Mcgeer (1988)
Rate of cell death in parkinsonism indicates active neuropathological processAnnals of Neurology, 24
K. Jellinger (1989)
Pathology of Parkinson’s Syndrome
D. Dexter, C. Carter, F. Wells, F. Javoy‐Agid, Y. Agid, A. Lees, P. Jenner, C. Marsden (1989)
Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's DiseaseJournal of Neurochemistry, 52
J. Chen, P. Hardy, M. Clauberg, J. Joshi, J. Parravano, J. Deck, R. Henkelman, L. Becker, W. Kucharczyk (1989)
T2 values in the human brain: comparison with quantitative assays of iron and ferritin.Radiology, 173 2
M. Youdim, D. Ben-Shachar, S. Yehuda, P. Riederer (1990)
The role of iron in the basal ganglion.Advances in neurology, 53
(1990)
Der NigraprozeJ-Ausloser der Parkinson-Krankheit
Hallgren Hallgren, Sourander Sourander (1958)
The effect of age on the non‐haem iron in human brainJ. Neurochem., 3
K. Rajan, R. Colburn, J. Davis (1976)
Distribution of metal ions in the subcellular fractions of several rat brain areas.Life sciences, 18 4
P. Mcgeer, S. Itagaki, B. Boyes, E. Mcgeer (1988)
Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brainsNeurology, 38
(1984)
Improved , Fer - rozine - based reagent for the determination of serum iron ( trans - femn iron ) without deproteinisation
P. Riederer, E. Sofić, W. Rausch, B. Schmidt, G. Reynolds, K. Jellinger, M. Youdim (1989)
Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian BrainsJournal of Neurochemistry, 52
T. Nagatsu (1988)
[Biochemistry of Parkinson's disease].Seikagaku. The Journal of Japanese Biochemical Society, 60 5
B. Pilas, T. Sarna, B. Kalyanaraman, H. Swartz, H. Swartz (1988)
The effect of melanin on iron associated decomposition of hydrogen peroxide.Free radical biology & medicine, 4 5
G. Gomori (1936)
Microtechnical Demonstration of Iron: A Criticism of its Methods.The American journal of pathology, 12 5
Therapie. 2. Auflage
Gomori Gomori (1936)
Microtechnical demonstration of ironAm. J. Pathol., 12
(1988)
Increased iron
A. Boobis, D. Fawthrop, D. Davies (1989)
Mechanisms of cell death.Trends in pharmacological sciences, 10 7
Sofic Sofic, Riederer Riederer, Heinsen Heinsen, Beckmann Beckmann, Reynolds Reynolds, Hebenstreit Hebenstreit, Youdim Youdim (1988)
Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brainJ. Neural Transm., 74
P. Riederer, E. Sofic, W. Rausch, P. Kruzik, M. Youdim (1985)
Dopaminforschung heute und morgen - L-Dopa in der Zukunft
D. Berg, P. Riederer (1980)
Die Parkinson-Krankheit
(1990)
The neuropharmacology
C. Konradi, P. Riederer, H. Heinsen (1989)
Histochemistry of MAO subtypes in the brainstem of humans: a relation to the radical hypothesis of Parkinson’s disease?
Zaleska Zaleska, Nagy Nagy, Floyd Floyd (1989)
Iron‐induced lipid peroxidation and inhibition of dopamine synthesis in striatum synaptosomesNeurochem. Res., 14
J. Hill, R. Switzer (1984)
The regional distribution and cellular localization of iron in the rat brainNeuroscience, 11
(1984)
Early iron - deficiency causes an irreversible diminution of dopamine D 2 receptor
M. Youdim (1989)
Dopaminergic neurotransmission and status of brain iron
H. Spatz (1922)
Über den eisennachweis im gehirn, besonders in zentren des extrapyramidal-motorischen systems. I. TeilZeitschrift für die gesamte Neurologie und Psychiatrie, 77
Agid Y. (1990)
99
B. Hallgren, P. Sourander (1958)
THE EFFECT OF AGE ON THE NON‐HAEMIN IRON IN THE HUMAN BRAINJournal of Neurochemistry, 3
(1960)
Verteilung von Noradrenalin und Dopamin im Gehirn des Menschen und ihr Verhalten bei Erkrankungen des extrapyramidalen Systems
K. Earle (1968)
Studies on Parkinson's disease including x-ray fluorescent spectroscopy of formalin fixed brain tissue.Journal of neuropathology and experimental neurology, 27 1
C. Konradi, J. Kornhuber, L. Froelich, J. Fritze, H. Heinsen, H. Beckmann, E. Schulz, P. Riederer (1989)
Demonstration of monoamine oxidase-A and -B in the human brainstem by a histochemical techniqueNeuroscience, 33
A. Graybiel, E. Hirsch, Yves Agid (1990)
The nigrostriatal system in Parkinson's disease.Advances in neurology, 53
D. Dexter, F. Wells, F. Agid, Y. Agid, A. Lees, P. Jenner, C. Marsden (1987)
INCREASED NIGRAL IRON CONTENT IN POSTMORTEM PARKINSONIAN BRAINThe Lancet, 330
(1984)
Monoamine oxidase and parkinsonism
Abstract: Histochemical and biochemical determinations of total iron, iron (II), and iron (III) contents in brain regions from Parkinson's and Alzheimer's diseases have demonstrated a selective increase of total iron content in parkinsonian substantia nigra zona compacta but not in the zona reticulata. The increase of iron content is mainly in iron (III). The ratio of iron (II):iron (III) in zona compacta changes from almost 2:1 to 1:2. This change is thought to be relevant and may contribute to the selective elevation of basal lipid peroxidation in substantia nigra reported previously. Iron may be available in a free state and thus can participate in autooxidation of dopamine with the resultant generation of H2O2 and oxygen free radicals.
Journal of Neurochemistry – Wiley
Published: Mar 1, 1991
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