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Z. Madhun, D. Goldthwait, D. McKay, U. Hopfer, J. Douglas (1991)
An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells.The Journal of clinical investigation, 88 2
Johannes Norgauer, Eckhard Kownatzki, Roland Seifert, K. Aktories (1988)
Botulinum C2 toxin ADP-ribosylates actin and enhances O2- production and secretion but inhibits migration of activated human neutrophils.The Journal of clinical investigation, 82 4
Thomas (1961)
10.1007/BF00736504Histochemistry, 2
K. Minneman, L. Iversen (1976)
Enkephalin and opiate narcotics increase cyclic GMP accumulation in slices of rat neostriatumNature, 262
J. Drapier, J. Hibbs (1986)
Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible.The Journal of clinical investigation, 78 3
J. Koh, S. Peters, D. Choi (1986)
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity.Science, 234 4772
R. Iyengar, D. Stuehr, M. Marletta (1987)
Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.Proceedings of the National Academy of Sciences of the United States of America, 84 18
D. Stuehr, H. Cho, N. Kwon, Mary Weise, C. Nathan (1991)
Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein.Proceedings of the National Academy of Sciences of the United States of America, 88 17
S. Ferreira, I. Duarte, B. Lorenzetti (1991)
Molecular base of acetylcholine and morphine analgesia.Agents and actions. Supplements, 32
J. Garthwaite, S. Charles, R. Chess-Williams (1988)
Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brainNature, 336
R. Kilbourn, S. Steven, GROSSf, A. Jubran, James Adams, O. Griffith, Roberto Levis, R. Lodato
hypotension: Implications for the involvement of nitric oxide
Richard Knowles, M. Salter, S. Brooks, S. Moncada (1990)
Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat.Biochemical and biophysical research communications, 172 3
F. Antoni, G. Dayanithi (1989)
Guanosine 3':5'cyclic monophosphate and activators of guanylate cyclase inhibit secretagogue-induced corticotropin release by rat anterior pituitary cells.Biochemical and biophysical research communications, 158 3
S. Vincent, O. Johansson, T. Hökfelt, L. Skirboll, R. Elde, L. Terenius, J. Kimmel, M. Goldstein (1983)
NADPH‐diaphorase: A selective histochemical marker for striatal neurons containing both somatostatin‐ and avian pancreatic polypeptide (APP)‐like immunoreactivitiesJournal of Comparative Neurology, 217
D. Stuehr, O. Fasehun, N. Kwon, S. Gross, J. González, R. Levi, C. Nathan (1991)
Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs 1The FASEB Journal, 5
Kortaro Tanaka, F. Gotoh, S. Gomi, S. Takashima, B. Mihara, T. Shirai, Sigeru Nogawa, E. Nagata (1991)
Inhibition of nitric oxide synthesis induces a significant reduction in local cerebral blood flow in the ratNeuroscience Letters, 127
M. Marletta (1989)
Nitric oxide: biosynthesis and biological significance.Trends in biochemical sciences, 14 12
J. Hibbs, R. Taintor, Z. Vavr̆ín (1984)
Iron depletion: possible cause of tumor cell cytotoxicity induced by activated macrophages.Biochemical and biophysical research communications, 123 2
J. Vente, J. Bol, H. Steinbusch (1989)
Localization of cGMP in the cerebellum of the adult rat: an immunohistochemical studyBrain Research, 504
J. Donaldson, R. Kahn, J. Lippincott-Schwartz, R. Klausner (1991)
Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein.Science, 254 5035
Kilbourn (1990)
10.1073/pnas.87.9.3629Proc Natl Acad Sci USA, 87
Dawson TM (1991)
Nitric oxide synthase/NADPH diaphorase neurons: role in neurotoxicitySoc Neurosci Abstr, 17
B. Mayer, Mathias John, Burghard Heinzel, E. Werner, H. Wachter, G. Schultz, E. Böhme (1991)
Brain nitric oxide synthase is a biopterin‐ and flavin‐containing multi‐functional oxido‐reductaseFEBS Letters, 288
T. Serafini, L. Orci, M. Amherdt, M. Brunner, R. Kahn, James Rothmant (1991)
ADP-Ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: A novel role for a GTP-binding proteinCell, 67
J. Hibbs, Z. Vavr̆ín, R. Taintor (1987)
L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.Journal of immunology, 138 2
G. Boeckxstaens, P. Pelckmans, H. Bult, J. Man, A. Herman, Y. Maercke (1991)
Evidence for nitric oxide as mediator of non‐adrenergic, non‐cholinergic relaxations induced by ATP and GABA in the canine gutBritish Journal of Pharmacology, 102
P. Chan, L. Chu, S. Chen, E. Carlson, C. Epstein (1990)
Reduced neurotoxicity in transgenic mice overexpressing human copper-zinc-superoxide dismutase.Stroke, 21 11 Suppl
J. Farah, T. Rao, S. Mick, K. Coyne, S. Iyengar (1991)
N-methyl-D-aspartate treatment increases circulating adrenocorticotropin and luteinizing hormone in the rat.Endocrinology, 128 4
R. Palmer, D. Ashton, S. Moncada (1988)
Vascular endothelial cells synthesize nitric oxide from L-arginineNature, 333
D. Bredt, P. Hwang, C. Glatt, C. Lowenstein, R. Reed, S. Snyder (1991)
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductaseNature, 351
P. Andersson, V. Perry, Stephen Gordon (1991)
The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degenerationNeuroscience, 42
J. Ahlner, Rolf Andersson, K. Torfgård, K. Axelsson (1991)
Organic nitrate esters: clinical use and mechanisms of actions.Pharmacological reviews, 43 3
Faraci FM (1990)
Role of nitric oxide in regulation of basilar artery tone in vivoAm. J Physiol, 255
S. Moncada, R. Palmer, E. Higgs (1989)
Biosynthesis of nitric oxide from L-arginine. A pathway for the regulation of cell function and communication.Biochemical pharmacology, 38 11
C. Köhler, Lars Eriksson, T. Hansson, M. Warner, Jan Åke-Gustafsson (1988)
Immunohistochemical localization of cytochrome P-450 in the rat brainNeuroscience Letters, 84
W. Arnold, C. Mittal, S. Katsuki, F. Murad (1977)
Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations.Proceedings of the National Academy of Sciences of the United States of America, 74 8
C. Lyons, Gregory Orloff, J. Cunningham (1992)
Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.The Journal of biological chemistry, 267 9
D. Stuehr, C. Nathan (1989)
Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cellsThe Journal of Experimental Medicine, 169
M. Nakane, M. Ichikawa, T. Deguchi (1983)
Light and electron microscopic demonstration of guanylate cyclase in rat brainBrain Research, 273
J. Vente, H. Steinbusch, J. Schipper (1987)
A new approach to immunocytochemistry of 3′,5′-cyclic guanosine monophosphate: Preparation, specificity, and initial application of a new antiserum against formaldehyde-fixed 3′,5′-cyclic guanosine monophosphateNeuroscience, 22
S. Eriksson, B. Appelgren, M. Rundgren, B. Andersson (1982)
Vasopressin release in response to intracerebroventricular L-alanine and L-arginine, and its dependence upon CSF NaCl concentration.Acta physiologica Scandinavica, 116 1
E. Schuman, D. Madison (1991)
A requirement for the intercellular messenger nitric oxide in long-term potentiation.Science, 254 5037
S. Moncada, R. Palmer, E. Higgs (1991)
Nitric oxide: physiology, pathophysiology, and pharmacology.Pharmacological reviews, 43 2
Nozaki (1992)
10.1038/jcbfm.1993.9
H. Bult, G. Boeckxstaens, P. Pelckmans, F. Jordaens, Y. Maercke, A. Herman (1990)
Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitterNature, 345
Berklemans (1989)
10.1007/BF00315967Histochemistry, 93
K. Nozaki, S. Okamoto, H. Yanamoto, H. Kikuchi (1990)
Red blood cells are essential for late vasospasm following experimentally induced subarachnoid hemorrhage in dogs.Neurologia medico-chirurgica, 30 1
D. Wink, Kasprzak Ks, C. Maragos, R. Elespuru, M. Misra, T. Dunams, Cebula Ta, Koch Wh, Andrews Aw, Allen Js (1991)
DNA deaminating ability and genotoxicity of nitric oxide and its progenitors.Science, 254 5034
D. Stuehr, Steven Gross, I. Sakuma, Roberto Levi, Carl Nathan (1989)
Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxideThe Journal of Experimental Medicine, 169
Alasdair Gaw, Alasdair Gaw, J. Aberdeen, P. Humphrey, R. Wadsworth, Geoffrey Burnstock (1991)
Relaxation of sheep cerebral arteries by vasoactive intestinal polypeptide and neurogenic stimulation: inhibition by l‐NG‐monomethyl arginine in endothelium‐denuded vesselsBritish Journal of Pharmacology, 102
N. Kwon, C. Nathan, D. Stuehr (1989)
Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages.The Journal of biological chemistry, 264 34
J. Nowicki, D. Duval, H. Poignet, Bernard Scatton (1991)
Nitric oxide mediates neuronal death after focal cerebral ischemia in the mouse.European journal of pharmacology, 204 3
J. Beckman, Tanya Beckman, Jun Chen, P. Marshall, B. Freeman (1990)
Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.Proceedings of the National Academy of Sciences of the United States of America, 87
D. Bredt, P. Hwang, S. Snyder (1990)
Localization of nitric oxide synthase indicating a neural role for nitric oxideNature, 347
Nyoun Kwon, Carl Nathan, C. Gilker, Owen Griffith, Dwight Matthews, D. Stuehr (1990)
L-citrulline production from L-arginine by macrophage nitric oxide synthase. The ureido oxygen derives from dioxygen.The Journal of biological chemistry, 265 23
J. Pollock, U. Förstermann, J. Mitchell, T. Warner, Harald Schmidt, M. Nakane, F. Murad (1991)
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.Proceedings of the National Academy of Sciences of the United States of America, 88 23
Solomon Snyder, D. Bredt (1991)
Nitric oxide as a neuronal messenger.Trends in pharmacological sciences, 12 4
D. Giulian, K. Vaca, C. Noonan (1990)
Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1Science, 250
K. Shibuki, D. Okada (1991)
Endogenous nitric oxide release required for long-term synaptic depression in the cerebellumNature, 349
Rajfer Rajfer, Aronson Aronson, Bush Bush (1992)
Nitric oxide as a mediator of the corpus cavernosum in response to nonadrenergic noncholinergic transmissionN Engl J Med, 326
D. Paupardin-Tritsch, C. Hammond, H. Gerschenfeld, A. Nairn, P. Greengard (1986)
cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neuronesNature, 323
G. Werner-Felmayer, E. Werner, Dietmar Fuchs, A. Hausen, G. Reibnegger, H. Wachter (1990)
Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblastsThe Journal of Experimental Medicine, 172
D. Light, E. Schwiebert, K. Karlson, B. Stanton (1989)
Atrial natriuretic peptide inhibits a cation channel in renal inner medullary collecting duct cells.Science, 243 4889
Acetylcholine induces peripheral analgesia by the release of nitric oxide
R. Duman, Rose Terwilliger, Eric Nestler (1991)
Endogenous ADP‐Ribosylation in Brain: Initial Characterization of Substrate ProteinsJournal of Neurochemistry, 57
P. Wood, M. Emmett, T. Rao, J. Cler, S. Mick, S. Iyengar (1990)
Inhibition of Nitric Oxide Synthase Blocks N‐Methyl‐D‐Aspartate‐, Quisqualate‐, Kainate‐, Harmaline‐, and Pentylenetetrazole‐Dependent Increases in Cerebellar Cyclic GMP In VivoJournal of Neurochemistry, 55
M. Ramagopal, H. Leighton (1989)
Effects of NG-monomethyl-L-arginine on field stimulation-induced decreases in cytosolic Ca2+ levels and relaxation in the rat anococcygeus muscle.European journal of pharmacology, 174 2-3
V. Chan‐Palay, S. Palay (1979)
Immunocytochemical localization of cyclic GMP: light and electron microscope evidence for involvement of neuroglia.Proceedings of the National Academy of Sciences of the United States of America, 76 3
D. Granger, A. Lehninger (1982)
Sites of inhibition of mitochondrial electron transport in macrophage- injured neoplastic cellsThe Journal of Cell Biology, 95
L. Ignarro, P. Bush, G. Buga, K. Wood, J. Fukuto, J. Rajfer (1990)
Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle.Biochemical and biophysical research communications, 170 2
Q. Xie, H. Cho, J. Calaycay, R. Mumford, K. Swiderek, Terry Lee, A. Ding, Tiffany Troso, C. Nathan (1992)
Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.Science, 256 5054
O. Eugster (1989)
History of Meteorites from the Moon Collected in AntarcticaScience, 245
C. Moine, E. Normand, Bertrand Bloch (1991)
Phenotypical characterization of the rat striatal neurons expressing the D1 dopamine receptor gene.Proceedings of the National Academy of Sciences of the United States of America, 88
J. Gally, P. Montague, G. Reeke, Gerald Edelman (1990)
The NO hypothesis: possible effects of a short-lived, rapidly diffusible signal in the development and function of the nervous system.Proceedings of the National Academy of Sciences of the United States of America, 87 9
C. Poole, D. Carter, M. Vallejo, S. Lightman (1987)
Atrial natriuretic factor inhibits the stimulated in-vivo and in-vitro release of vasopressin and oxytocin in the rat.The Journal of endocrinology, 112 1
(1989)
cGMP immuno - cytochemistry in aorta , kidney , retina and brain tissues of the rat after perfusion with nitroptusside
R. Gerzer, A. Brash, J. Hardman (1986)
Activation of soluble guanylate cyclase by arachidonic acid and 15-lipoxygenase products.Biochimica et biophysica acta, 886 3
J. Daly (1977)
Cyclic Nucleotides in the Nervous System
M. Warner, C. Köhler, T. Hansson, J. Gustafsson (1988)
Regional Distribution of Cytochrome P‐450 in the Rat Brain: Spectral Quantitation and Contribution of P‐450b,e and P‐450c,dJournal of Neurochemistry, 50
Y. Izumi, A. Benz, D. Clifford, C. Zorumski (1992)
Nitric oxide inhibitors attenuate N-methyl-d-aspartate excitotoxicity in rat hippocampal slicesNeuroscience Letters, 135
Lamas S (1992)
Molecular characterization of constitutive nitric oxide synthase: evidence for a family of related genesClin Res, 40
W. Song, A. Brash (1991)
Purification of an allene oxide synthase and identification of the enzyme as a cytochrome P-450.Science, 253 5021
G. Böhme, C. Bon, J. Stutzmann, A. Doble, J. Blanchard (1991)
Possible involvement of nitric oxide in long-term potentiation.European journal of pharmacology, 199 3
Tayeh (1989)
10.1016/S0021-9258(19)47163-9J Biol Chem, 264
Tayeh Tayeh, Marletta Marletta (1989)
Macrophage oxidation of L‐arginine to nitric oxide, nitrite, and nitrateJ Biol Chem, 264
M. Moskowitz, Damianos Sakas, E. Wei, M. Kano, M. Buzzi, Christopher Ogilvy, H. Kontos (1989)
Postocclusive cerebral hyperemia is markedly attenuated by chronic trigeminal ganglionectomy.The American journal of physiology, 257 5 Pt 2
M. Beal, N. Kowall, D. Ellison, M. Mazurek, Kenton Swartz, Joseph Martin (1986)
Replication of the neurochemical characteristics of Huntington's disease by quinolinic acidNature, 321
Ulrich Förstermann, L. Gorsky, Jennifer Pollock, Harald Schmidt, Michael Heller, Ferid Murad (1990)
Regional distribution of EDRF/NO-synthesizing enzyme(s) in rat brain.Biochemical and biophysical research communications, 168 2
M. Radomski, R. Palmer, S. Moncada (1990)
An L-arginine/nitric oxide pathway present in human platelets regulates aggregation.Proceedings of the National Academy of Sciences of the United States of America, 87 13
George Foster, Peter Sanderson, Peter Roberts (1983)
β-Adrenergic receptor-mediated increases in mouse cerebellar cyclic GMP levels in vitroEuropean Journal of Pharmacology, 87
R. Furchgott (1990)
The 1989 Ulf von Euler lecture. Studies on endothelium-dependent vasodilation and the endothelium-derived relaxing factor.Acta physiologica Scandinavica, 139 2
Thomas Thomas, Pearse Pearse (1964)
The solitary active cells. Histochemical demonstration of damage‐resistant nerve cells with a TPNdiaphorase reactionActa Neuropathol (Berl), 3
B. Meldrum, J. Garthwaite (1990)
Excitatory amino acid neurotoxicity and neurodegenerative disease.Trends in pharmacological sciences, 11 9
M. Graziano, A. Gilman (1987)
Guanine nucleotide-binding regulatory proteins; mediators of transmembrane signalingTrends in Pharmacological Sciences, 8
S. East, J. Garthwaite (1991)
NMDA receptor activation in rat hippocampus induces cyclic GMP formation through the l-arginine-nitric oxide pathwayNeuroscience Letters, 123
(1992)
Carbon monoxide as a physiological messenger indicated by heme oxygenase localizations and cyclic GMP regulation
Izumi Izumi, Benz Benz, Clifford Clifford, Zorumski Zorumski (1992)
Nitric oxide inhibitors attenuat N‐methyl‐D‐asparate excitotoxicity in rat hippocampal slicesNeurosci Lett, 135
(1992)
Possible origins and distribution of immunoreactive nitric oxide synthase - containing nerve fibers in rat and human cerebral arteries
B. Brüne, E. Lapetina (1989)
Activation of a cytosolic ADP-ribosyltransferase by nitric oxide-generating agents.The Journal of biological chemistry, 264 15
S. Sagar, D. Ferriero (1987)
NADPH diaphorase activity in the posterior pituitary: relation to neuronal functionBrain Research, 400
JY Koh, D. Choi (1988)
Vulnerability of cultured cortical neurons to damage by excitotoxins: differential susceptibility of neurons containing NADPH-diaphorase, 8
L. Ignarro (1990)
Biosynthesis and metabolism of endothelium-derived nitric oxide.Annual review of pharmacology and toxicology, 30
L. Ignarro, P. Kadowitz (1985)
The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation.Annual review of pharmacology and toxicology, 25
T. Cornwell, T. Lincoln (1989)
Regulation of intracellular Ca2+ levels in cultured vascular smooth muscle cells. Reduction of Ca2+ by atriopeptin and 8-bromo-cyclic GMP is mediated by cyclic GMP-dependent protein kinase.The Journal of biological chemistry, 264 2
D. Bredt, C. Glatt, P. Hwang, M. Fotuhi, T. Dawson, S. Snyder (1991)
Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphoraseNeuron, 7
K. Nozaki, S. Okamoto, Y. Uemura, H. Kikuchi, N. Mizuno (1990)
Erythrocytes suppress calcitonin gene-related peptide- and vasoactive intestinal polypeptide-like immunoreactivities in cerebrovascular nerve fibers after subarachnoid hemorrhageNeuroscience Letters, 110
S. Puri, P. Choma, L. Volicer (1978)
Cyclic nucleotide levels in the rat striatum and cerebellum--in vivo effects of dopamine and acetylcholine receptor agonists and antagonists.Biochemical pharmacology, 27 19
J. Ferrendelli, M. Chang, D. Kinscherf (1974)
ELEVATION OF CYCLIC GMP LEVELS IN CENTRAL NERVOUS SYSTEM BY EXCITATORY AND INHIBITORY AMINO ACIDS 1Journal of Neurochemistry, 22
Kazuhiko Nozaki, Shinichiro Okamoto, Y. Uemura, Haruhiko Kikuchi, Noboru Mizuno (1990)
Vascular relaxation properties of calcitonin gene-related peptide and vasoactive intestinal polypeptide in subarachnoid hemorrhage.Journal of neurosurgery, 72 5
H. Urbanski, S. Ojeda (1990)
A role for N-methyl-D-aspartate (NMDA) receptors in the control of LH secretion and initiation of female puberty.Endocrinology, 126 3
J. Krahenbuhl, Jack Remington (1974)
The role of activated macrophages in specific and nonspecific cytostasis of tumor cells.Journal of immunology, 113 2
J. Garthwaite, G. Garthwaite, R. Palmer, S. Moncada (1989)
NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices.European journal of pharmacology, 172 4-5
V. Perry, S. Gordon (1988)
Macrophages and microglia in the nervous systemTrends in Neurosciences, 11
Carter DA (1989)
Cyclic nucleotide dynamics in the rat hypothalamus during osmotic stimulation in vivo and in vitro release of vasopressin and oxtocin in the ratJ Endocrinol, 112
V. Gay, T. Plant (1987)
N-methyl-D,L-aspartate elicits hypothalamic gonadotropin-releasing hormone release in prepubertal male rhesus monkeys (Macaca mulatta).Endocrinology, 120 6
Noboru Toda, T. Okamura (1990)
Possible role of nitric oxide in transmitting information from vasodilator nerve to cerebroarterial muscle.Biochemical and biophysical research communications, 170 1
Naomasa Miki, Yasunori Kawabe, Kinya Kuriyama (1977)
Activation of cerebral guanylate cyclase by nitric oxide.Biochemical and biophysical research communications, 75 4
Y. Yui, Ryuichi Hattori, Kunihiko Kosuga, H. Eizawa, K. Hiki, S. Ohkawa, K. Ohnishi, S. Terao, Chuichi Kawai (1991)
Calmodulin-independent nitric oxide synthase from rat polymorphonuclear neutrophils.The Journal of biological chemistry, 266 6
de Vente de Vente, Steinbusch Steinbusch, Schipper Schipper (1987)
A new approach to immunocytochemistry of 3′,5′‐cyclic guanosine monophosphateNeuroscience, 22
R. Freedman, D. Taylor, A. Seiger, L. Olson, B. Hoffer (1979)
Seizures and related epileptiform activity in hippocampus transplanted to the anterior chamber of the eye: Modulation by cholinergic and adrenergic inputAnnals of Neurology, 6
D. Doerner, B. Alger (1988)
Cyclic GMP depresses hippocampal Ca2+ current through a mechanism independent of cGMP-dependent protein kinaseNeuron, 1
T. Murphy, M. Long, J. Coyle (1991)
Enhanced NAD(P)H:Quinone Reductase Activity Prevents Glutamate Toxicity Produced by Oxidative StressJournal of Neurochemistry, 56
J. Beavo, J. Beavo, D. Reifsnyder, D. Reifsnyder (1990)
Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors.Trends in pharmacological sciences, 11 4
Thomas (1964)
10.1007/BF00684399Acta Neuropathol (Berl), 3
Boeckxstaens Boeckxstaens, Pelckmans Pelckmans, Bult Bult (1990)
Evidence for nitric oxide as mediator of non‐adrenergic non‐cholinergic neurotransmitterNature, 345
Toshio Nakaki, M. Nakayama, R. Kato (1990)
Inhibition by nitric oxide and nitric oxide-producing vasodilators of DNA synthesis in vascular smooth muscle cells.European journal of pharmacology, 189 6
M. Wharton, D. Granger, D. Durack (1988)
Mitochondrial iron loss from leukemia cells injured by macrophages. A possible mechanism for electron transport chain defects.Journal of immunology, 141 4
E. Böhme, G. Grossmann, J. Herz, A. Mülsch, C. Spies, G. Schultz (1984)
Regulation of cyclic GMP formation by soluble guanylate cyclase: stimulation by NO-containing compounds.Advances in cyclic nucleotide and protein phosphorylation research, 17
M. Marletta, P. Yoon, R. Iyengar, C. Leaf, J. Wishnok (1988)
Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate.Biochemistry, 27 24
J. Drapier, Jr Hibbs (1988)
Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells.Journal of immunology, 140 8
T. Dawson, D. Bredt, M. Fotuhi, P. Hwang, S. Snyder (1991)
Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues.Proceedings of the National Academy of Sciences of the United States of America, 88 17
A. Tøttrup, D. Svane, A. Forman (1991)
Nitric oxide mediating NANC inhibition in opossum lower esophageal sphincter.The American journal of physiology, 260 3 Pt 1
Y. Yui, Ryuichi Hattori, Kunihiko Kosuga, H. Eizawa, K. Hiki, Chuichi Kawai (1991)
Purification of nitric oxide synthase from rat macrophages.The Journal of biological chemistry, 266 19
Richard Knowles, M. Palacios, R. Palmer, S. Moncada (1989)
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.Proceedings of the National Academy of Sciences of the United States of America, 86 13
M. Hanley, L. Iversen (1978)
Muscarinic cholinergic receptors in rat corpus striatum and regulation of guanosine cyclic 3',5'-monophosphate.Molecular pharmacology, 14 2
S. Murphy, R. Minor, G. Welk, D. Harrison (1990)
Evidence for an Astrocyte‐Derived Vasorelaxing Factor with Properties Similar to Nitric OxideJournal of Neurochemistry, 55
R. Rapoport, M. Draznin, F. Murad (1983)
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylationNature, 306
M. Acrophages, BY Keller (1973)
CYTOSTATIC ELIMINATION OF SYNGENEIC RAT TUMOR CELLS IN VITRO BY NONSPECIFICALLY ACTIVATED MACROPHAGESThe Journal of Experimental Medicine, 138
(1989)
Role of nitric oxide in regulation of basilar artery 254 : 1503 - 1 506 199 1 ; 349 : 326 - 328 2289 - 2296
R. Ferrante, N. Kowall, Beal Mf, E. Richardson, E. Bird, Jens Martin (1985)
Selective sparing of a class of striatal neurons in Huntington's disease.Science, 230 4725
K. Desai, W. Sessa, J. Vane (1991)
Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluidNature, 351
T. Deguchi (1977)
Endogenous activating factor for guanylate cyclase in synaptosomal-soluble fraction of rat brain.The Journal of biological chemistry, 252 21
R. Palmer, A. Ferrige, S. Moncada (1987)
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factorNature, 327
N. Toda, T. Okamura (1991)
Role of nitric oxide in neurally induced cerebroarterial relaxation.The Journal of pharmacology and experimental therapeutics, 258 3
Roger Smith, Claudine Louis, R. Kruszyna, H. Kruszyna (1991)
Acute neurotoxicity of sodium azide and nitric oxide.Fundamental and applied toxicology : official journal of the Society of Toxicology, 17 1
D. Choi (1990)
Cerebral hypoxia: some new approaches and unanswered questions, 10
Gerzer Gerzer, Brash Brash, Hardman Hardman (1986)
Activation of soluble guanylate cyclase by arachidonic acid and 15‐lipoxygenase productsBiochem Biophys Acta, 886
H. Kinouchi, C. Epstein, T. Mizui, E. Carlson, Sylvia Chen, Pak Chan (1991)
Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.Proceedings of the National Academy of Sciences of the United States of America, 88 24
M. Tayeh, M. Marletta (1989)
Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor.The Journal of biological chemistry, 264 33
D. Bredt, C. Ferris, Solomon Snyder (1992)
Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites.The Journal of biological chemistry, 267 16
Gerald Marks, James Brien, K. Nakatsu, B. McLaughlin (1991)
Does carbon monoxide have a physiological function?Trends in pharmacological sciences, 12 5
L. Ignarro, K. Wood, M. Wolin (1984)
Regulation of purified soluble guanylate cyclase by porphyrins and metalloporphyrins: a unifying concept.Advances in cyclic nucleotide and protein phosphorylation research, 17
T. O’Dell, R. Hawkins, E. Kandel, O. Arancio (1991)
Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.Proceedings of the National Academy of Sciences of the United States of America, 88 24
E. Southam, Stephen East, John Garthwaite (1991)
Excitatory Amino Acid Receptors Coupled to the Nitric Oxide/Cyclic GMP Pathway in Rat Cerebellum During DevelopmentJournal of Neurochemistry, 56
Rafael Radil, J. Beckman, K. Bush, B. Freeman (1991)
Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide.The Journal of biological chemistry, 266 7
Steven Vincent, Keiji Satoh, David Armstrong, H. Fibiger (1983)
NADPH-diaphorase: A selective histochemical marker for the cholinergic neurons of the pontine reticular formationNeuroscience Letters, 43
A. Reyes, J. Luckhaus, M. Ferin (1990)
Unexpected inhibitory action of N-methyl-D,L-aspartate or luteinizing hormone release in adult ovariectomized rhesus monkeys: a role of the hypothalamic-adrenal axis.Endocrinology, 127 2
G. Foster, P. Roberts (1980)
Pharmacology of excitatory amino acid receptors mediating the stimulation of rat cerebellar cyclic GMP leveleLife Sciences, 27
J. Hibbs, R. Taintor, Z. Vavr̆ín (1987)
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite.Science, 235 4787
M. Kano, M. Moskowitz, M. Yokota (1991)
Parasympathetic Denervation of Rat Pial Vessels Significantly Increases Infarction Volume following Middle Cerebral Artery OcclusionJournal of Cerebral Blood Flow & Metabolism, 11
L. Ignarro, K. Wood (1987)
Activation of purified soluble guanylate cyclase by arachidonic acid requires absence of enzyme-bound heme.Biochimica et biophysica acta, 928 2
D. Granger, R. Taintor, J. Cook, J. Hibbs (1980)
Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration.The Journal of clinical investigation, 65 2
D. Salvemini, G. Nucci, R. Gryglewski, J. Vane (1989)
Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor.Proceedings of the National Academy of Sciences of the United States of America, 86 16
Alan Gibson, S. Mirzazadeh, Adrian Hobbs, Philip Moore (1990)
l‐NG‐monomethyl arginine and l‐NG‐nitro arginine inhibit non‐adrenergic, non‐cholinergic relaxation of the mouse anococcygeus muscleBritish Journal of Pharmacology, 99
R. Curran, T. Billiar, '. Stuehr, K. Hofmann, R. Simmons (1989)
Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cellsThe Journal of Experimental Medicine, 170
Y. Uemura, N. Kowall, M. Beal (1990)
Selective sparing of NADPH‐diaphorase–somatostatin–neuropeptide Y neurons in ischemic gerbil striatumAnnals of Neurology, 27
V. Mollace, G. Bagetta, G. Nisticó (1991)
Evidence that L-arginine possesses proconvulsant effects mediated through nitric oxide.Neuroreport, 2 5
D. Bredt, S. Snyder (1990)
Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.Proceedings of the National Academy of Sciences of the United States of America, 87 2
E. Fesenko, S. Kolesnikov, A. Lyubarsky (1985)
Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segmentNature, 313
J. Lancaster, J. Hibbs (1990)
EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.Proceedings of the National Academy of Sciences of the United States of America, 87
R. Kilbourn, A. Jubran, S. Gross, O. Griffith, R. Levi, James Adams, R. Lodato (1990)
Reversal of endotoxin-mediated shock by NG-methyl-L-arginine, an inhibitor of nitric oxide synthesis.Biochemical and biophysical research communications, 172 3
J. Rakoff, T. Siler, Y. Sinha, S. Yen (1973)
Prolactin and growth hormone release in response to sequential stimulation by arginine and synthetic TRF.The Journal of clinical endocrinology and metabolism, 37 5
(1991)
Projections of neurons with nitric oxide synthase immunoreactivity in the guinea - pig small intestine
E. Southam, J. Garthwaite (1991)
Climbing Fibres as a Source of Nitric Oxide in the CerebellumEuropean Journal of Neuroscience, 3
J. Goh, P. Pennefather (1989)
A pertussis toxin-sensitive G protein in hippocampal long-term potentiation.Science, 244 4907
M. Ariano, J. Lewicki, H. Brandwein, F. Murad (1982)
Immunohistochemical localization of guanylate cyclase within neurons of rat brain.Proceedings of the National Academy of Sciences of the United States of America, 79 4
Kapitulnik (1987)
10.1016/0306-4522(87)90243-0Neuroscience, 20
J. Hibbs, R. Taintor, Z. Vavr̆ín, E. Rachlin (1988)
Nitric oxide: a cytotoxic activated macrophage effector molecule.Biochemical and biophysical research communications, 157 1
J. Gillespie, Xiaorong Liu, W. Martin (1989)
The effects of L‐arginine and NG‐monomethyl L‐arginine on the response of the rat anococcygeus muscle to NANC nerve stimulationBritish Journal of Pharmacology, 98
G. Trakshel, R. Kutty, M. Maines (1988)
Resolution of the rat brain heme oxygenase activity: absence of a detectable amount of the inducible form (HO-1).Archives of biochemistry and biophysics, 260 2
M. Ariano, S. Kenny (1989)
Striatal muscarinic receptors are associated with substance P and somatostatin containing neuronsBrain Research, 497
J. Ferrendelli, Ann Blank, R. Gross (1980)
Relationships between seizure activity and cyclic nucleotide levels in brainBrain Research, 200
V. Dawson, T. Dawson, E. London, D. Bredt, S. Snyder (1991)
Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.Proceedings of the National Academy of Sciences of the United States of America, 88 14
Ignarro Ignarro, Wood Wood (1987)
Activation of purified soluble guanylate cyclase by arachidonic acid requires absence of enzyme‐bound hemeBiochem Biophys Acta, 928
J. Giovanelli, K. Campos, S. Kaufman (1991)
Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine.Proceedings of the National Academy of Sciences of the United States of America, 88
Michael Chinkers, D. Garbers (1991)
Signal transduction by guanylyl cyclases.Annual review of biochemistry, 60
C. Ross, D. Bredt, S. Snyder (1990)
Messenger molecules in the cerebellumTrends in Neurosciences, 13
Tanaka Tanaka, Gotoh Gotoh, Gomi Gomi (1991)
Inhibition of nitric oxide synthesis induces a significant reduction in local cerebral blood flow in the ratNaurosci Lett, 127
A. Burnett, C. Lowenstein, D. Bredt, T. Chang, S. Snyder (1992)
Nitric oxide: a physiologic mediator of penile erection.Science, 257 5068
E. Bardana (1991)
Air pollutants.Allergy proceedings : the official journal of regional and state allergy societies, 12 3
C. Lowenstein, Charles Glatt, D. Bredt, S. Snyder (1992)
Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.Proceedings of the National Academy of Sciences of the United States of America, 89 15
G. Foster, P. Roberts (1980)
Pharmacology of excitatory amino acid receptors mediating the stimulation of rat cerebellar cyclic GMP levels in vitro.Life sciences, 27 3
B. Mayer, Mathias John, E. Böhme (1990)
Purification of a Ca2+/calmodulin‐dependent nitric oxide synthase from porcine cerebellumFEBS Letters, 277
Schuman Schuman, Madison Madison (1991)
The intercellular messenger nitric oxide is required for long‐term potentiationScience, 254
S. Lipton, N. Sucher, P. Kaiser, E. Dreyer (1991)
Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicityNeuron, 7
S. Inagaki, Keichiro Suzuki, N. Taniguchi, H. Takagi (1991)
Localization of Mn-superoxide dismutase (Mn-SOD) in cholinergic and somatostatin-containing neurons in the rat neostriatumBrain Research, 549
J. Garthwaite (1991)
Glutamate, nitric oxide and cell-cell signalling in the nervous systemTrends in Neurosciences, 14
L. Haglund, C. Köhler, T. Haaparanta, M. Goldstein, J. Gustafsson (1984)
Presence of NADPH-cytochrome P450 reductase in central catecholaminergic neuronesNature, 307
T. Deguchi, M. Yoshioka (1982)
L-Arginine identified as an endogenous activator for soluble guanylate cyclase from neuroblastoma cells.The Journal of biological chemistry, 257 17
B. Hope, G. Michael, K. Knigge, S. Vincent (1991)
Neuronal NADPH diaphorase is a nitric oxide synthase.Proceedings of the National Academy of Sciences of the United States of America, 88
Kilbourn Kilbourn, Gross Gross, Jubran Jubran (1990)
N G ‐Methyl‐L‐arginine inhibits tumor necrosis factor‐induecd hypotension: implications for the involvement of nitric oxideProc Natl Acad Sci USA, 87
D. Bredt, S. Snyder (1989)
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.Proceedings of the National Academy of Sciences of the United States of America, 86 22
J. Rajfer, W. Aronson, P. Bush, F. Dorey, L. Ignarro (1992)
Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic NeurotransmissionThe New England Journal of Medicine, 326
Kano M (1991)
Parasympathetic denervation of rat pial vessels significantly increases infarction volume following middle cerebral artery occlucionLab Invest, 11
Thomas Thomas, Pearse Pearse (1961)
The fine localization of dehydrogenases in the nervous systemHistochemistry, 2
R. Furchgott, J. Zawadzki (1980)
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineNature, 288
Understanding of the organization and function of a newly identified neuronal messenger molecule, nitric oxide, has progressed rapidly. Nitric oxide synthase has been purified and molecularly cloned from brain. Its localization is exclusively neuronal and endothelial. The catalytic activity of nitric oxide synthase accounts for the NADPH diaphorase staining of neurons that are uniquely resistant ot toxic insults and neurodegenerative disorders. Nitric oxide has diverse functions. In platelets it inhibits their aggregation, in macrophages it mediates cytotoxicity, and in blood vessels it acts as a vasodilator. In the nervous system nitric oxide may be the retrograde transmitter in long‐term potentiation. It is the “neurotransmitter” of cerebral vasodilator nerves and the inhibitory “neurotransmitter” of the motor neurons of the intestines. Nitric oxide in situations of excessive production may function as neurotoxin, suggesting a role for nitric oxide in neurodegenerative disorders.
Annals of Neurology – Wiley
Published: Sep 1, 1992
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