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References (9)
-
Mitchell (1982)
The angry back syndrome syndrome - the excited skin syndromeSemin Derm, 1
-
P. Osmundsen (1982)
Contact dermatitis to chlorhexidineContact Dermatitis, 8
-
(1982)
to chi or hex - idine -
(1972)
Eczematous contact al-CONTACT SENSITIVITY TO CHLORHEXIDINE lergy to chlorhexidine. Acta Dermato-venereologica -
(1982)
Contact dermatitis to chi or hexidine -
(1972)
Eczematous contact alCONTACT SENSITIVITY TO CHLORHEXIDINE lergy to chlorhexidine -
B. Ljunggren, H. Möller (1972)
Eczematous contact allergy to chlorhexidine.Acta dermato-venereologica, 52 4
-
Klaus Andersen, H. Maibach (1980)
Allergic reaction to drugs used topically.Clinical toxicology, 16 4
-
(1982)
The angry back syndrome - the excited skin syndrome
- Publisher
- Wiley
- Copyright
- Copyright © 1985 Wiley Subscription Services, Inc., A Wiley Company
- ISSN
- 0105-1873
- eISSN
- 1600-0536
- DOI
- 10.1111/j.1600-0536.1985.tb02504.x
- Publisher site
- See Article on Publisher Site
Abstract
In a joint study, 2061 patterns (1346 women and 715 men) were patch tested with chlorhexidine gluconate 1% in Water. included in a standard lest series. 4H patients (2.3%) showed a positive reaction. These were relatively marc common in men (3.2%) than in women (1.9%), Positive reactions were most common in patients with leg eczema (6.8%) or leg ulcer (10.9%). Of the 48 patients who were patch test positive. 14 (2 with leg ulcer) were retested with chlorhexidine gluconate 0.01 and 1%. Only one with a leg ulcer was positive. These findings indicate that false positive reactions, known as “the incited skin syndrome”, may arise from testing eczema patients in a standard series The sensitizing potential of chlorhexidine may be very low, but the potential in patients with an eczema or ulcer of the leg has to be further evaluated.
Journal
Contact Dermatitis – Wiley
Published: Jul 1, 1985