Access the full text.
Sign up today, get DeepDyve free for 14 days.
Adam Takos, Felix Jaffé, S. Jacob, J. Bogs, S. Robinson, A. Walker (2006)
Light-Induced Expression of a MYB Gene Regulates Anthocyanin Biosynthesis in Red Apples1Plant Physiology, 142
Tomoya Noritake, K. Kawakita, N. Doke (1996)
Nitric Oxide Induces Phytoalexin Accumulation in Potato Tuber TissuesPlant and Cell Physiology, 37
S. Gaisser, L. Heide (1996)
Inhibition and regulation of shikonin biosynthesis in suspension cultures of LithospermumPhytochemistry, 41
M. Tabata, H. Mizukami, N. Hiraoka, M. Konoshima (1974)
Pigment formation in callus cultures of Lithospermum erythrorhizonPhytochemistry, 13
J. Qi, Wen-Ju Zhang, Shao-hua Liu, Hong Wang, D. Sun, Guo-Hua Xu, M. Shi, Zhi Liu, Ming-sheng Zhang, Hui-ming Zhang, Yong-Hua Yang (2008)
Expression analysis of light-regulated genes isolated from a full-length-enriched cDNA library of Onosma paniculatum cell cultures.Journal of plant physiology, 165 14
B. Lange, K. Severin, A. Bechthold, L. Heide (1998)
Regulatory role of microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase for shikonin biosynthesis in Lithospermum erythrorhizon cell suspension culturesPlanta, 204
K. Yazaki, H. Matsuoka, Tomomi Ujihara, F. Sato (1999)
Shikonin Biosynthesis in Lithospermum erythrorhizonPlant Biotechnology, 16
Jianmin Zhao, ’. RobertL.Last (1996)
Coordinate regulation of the tryptophan biosynthetic pathway and indolic phytoalexin accumulation in Arabidopsis.The Plant cell, 8
L. Heide, M. Tabata (1987)
Enzyme activities in cell-free extracts of shikonin-producing Lithospermum erythrorhizon cell suspension culturesPhytochemistry, 26
B. Abbasi, Chunjie Tian, S. Murch, P. Saxena, Chunzhao Liu (2007)
Light-enhanced caffeic acid derivatives biosynthesis in hairy root cultures of Echinacea purpureaPlant Cell Reports, 26
Y. Yamaga, K. Nakanishi, H. Fukui, M. Tabata (1993)
Intracellular localization of p-hydroxybenzoate geranyltransferase, a key enzyme involved in shikonin biosynthesisPhytochemistry, 32
W Ning, R Cao (1995)
Biotechnology in agriculture and forestry 37: medicinal and aromatic plants IX
Hideo Honda, Tomoko Okamoto, Hiroaki Shimada (1996)
Isolation of a cDNA for a phosphoenolpyruvate carboxylase from a monocot CAM-plant, Aloe arborescens: structure and its gene expression.Plant & cell physiology, 37 6
Y.-H. Yang, H. Zhang, R. Cao (1999)
Effect of Brassinolide on Growth and Shikonin Formation in Cultured Onosma paniculatum CellsJournal of Plant Growth Regulation, 18
L. Modolo, F. Cunha, M. Braga, I. Salgado (2002)
Nitric Oxide Synthase-Mediated Phytoalexin Accumulation in Soybean Cotyledons in Response to the Diaporthe phaseolorumf. sp. meridionalis Elicitor1Plant Physiology, 130
J. Tepperman, Tong Zhu, H. Chang, X. Wang, P. Quail (2001)
Multiple transcription-factor genes are early targets of phytochrome A signalingProceedings of the National Academy of Sciences of the United States of America, 98
Shu-jing Wu, J. Qi, Wen-Ju Zhang, Shao-hua Liu, F. Xiao, Ming-sheng Zhang, Guo-Hua Xu, Wei-guang Zhao, M. Shi, Y. Pang, Heng-Guan Shen, Yong-Hua Yang (2009)
Nitric oxide regulates shikonin formation in suspension-cultured Onosma paniculatum cells.Plant & cell physiology, 50 1
K. Hahlbrock, D. Scheel (1989)
Physiology and Molecular Biology of Phenylpropanoid Metabolism, 40
K. Yazaki, M. Kunihisa, T. Fujisaki, F. Sato (2002)
Geranyl diphosphate:4-hydroxybenzoate geranyltransferase from Lithospermum erythrorhizon. Cloning and characterization of a ket enzyme in shikonin biosynthesis.The Journal of biological chemistry, 277 8
W. Ning, R. Cao (1996)
Onosma paniculatum : In Vitro Culture and the Production of Purple-Red Pigment
Y Yamamura, Y Ogihara, H Mizukami (2001)
Cinnamic acid 4-hydroxylase from Lithospermum erythrorhizon: cDNA cloning and gene expressionPlant Cell Rep, 20
Z. Wang, S. Li, R. Löscher, L. Heide (1997)
4-Coumaroyl coenzyme A 3-hydroxylase activity from cell cultures of Lithospermum erythrorhizon and its relationship to polyphenol oxidase.Archives of biochemistry and biophysics, 347 2
P. Quail (2002)
Photosensory perception and signalling in plant cells: new paradigms?Current opinion in cell biology, 14 2
Y. Fujita, Y. Hara, C. Suga, T. Morimoto (1981)
Production of shikonin derivatives by cell suspension cultures of Lithospermum erythrorhizonPlant Cell Reports, 1
M. Tani, H. Fukui, M. Shimomura, M. Tabata (1992)
Structure of endogenous oligogalacturonides inducing shikonin biosynthesis in Lithospermum cell culturesPhytochemistry, 31
K. Yazaki, Kenta Takeda, M. Tabata (1997)
Effects of Methyl Jasmonate on Shikonin and Dihydroechinofuran Production in Lithospermum Cell CulturesPlant and Cell Physiology, 38
K. Yazaki, Hideaki Matsuoka, K. Shimomura, Andreas Bechthold, Fumihiko Sato (2001)
A novel dark-inducible protein, LeDI-2, and its involvement in root-specific secondary metabolism in Lithospermum erythrorhizon.Plant physiology, 125 4
K. Touno, J. Tamaoka, Y. Ohashi, K. Shimomura (2005)
Ethylene induced shikonin biosynthesis in shoot culture of Lithospermum erythrorhizon.Plant physiology and biochemistry : PPB, 43 2
M. Matsuno, A. Nagatsu, Y. Ogihara, B. Ellis, H. Mizukami (2002)
CYP98A6 from Lithospermum erythrorhizon encodes 4‐coumaroyl‐4′‐hydroxyphenyllactic acid 3‐hydroxylase involved in rosmarinic acid biosynthesis 1FEBS Letters, 514
Zhi Liu, J. Qi, Lu Chen, Ming-sheng Zhang, Xiu-Qiang Wang, Y. Pang, Yong-Hua Yang (2005)
Effect of Light on Gene Expression and Shikonin Formation in Cultured Onosma Paniculatum CellsPlant Cell, Tissue and Organ Culture, 84
K. Yazaki, M. Kataoka, G. Honda, K. Severin, L. Heide (1997)
cDNA cloning and gene expression of phenylalanine ammonia-lyase in Lithospermum erythrorhizon.Bioscience, biotechnology, and biochemistry, 61 12
O. Gamborg, R. Miller, K. Ojima (1968)
Nutrient requirements of suspension cultures of soybean root cells.Experimental cell research, 50 1
L. Heide, N. Nishioka, H. Fukui, M. Tabata (1989)
Enzymatic regulation of shikonin biosynthesis in Lithospermum erythrorhizon cell culturesPhytochemistry, 28
J. Wang, Jian Wu (2004)
Involvement of nitric oxide in elicitor-induced defense responses and secondary metabolism of Taxus chinensis cells.Nitric oxide : biology and chemistry, 11 4
V. Papageorgiou, A. Assimopoulou, E. Couladouros, D. Hepworth, K. Nicolaou (1999)
The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products.Angewandte Chemie, 38 3
K. Yazaki, H. Matsuoka, Tomomi Ujihara, F. Sato (2001)
Shikonin Biosynthesis in Lithospermum erythrorhizon: Light- induced Negative Regulation of Secondary Metabolism
When cells of Lithospermum erythrorhizon were transferred from B5 solid medium into M9 liquid medium and grown in the dark, they produced and accumulated shikonin and its derivatives; meanwhile, transcripts of PAL, 4CL, HMGR, PGT, and CYP98A6 were rapidly induced within 2 h, peaking within 6 h, and then decreasing over time. However, when L. erythrorhizon cells were cultured in M9 medium and grown under white light, a negative regulator for the biosynthesis of shikonin and its derivatives, the “stimulating effect” of the medium transition on the transcription of these genes was also displayed with similar patterns over 24 h of culture period. To investigate the time-dependent effect of light signals on regulating gene transcription, expression analysis of L. erythrorhizon dark-inducible genes LeDI-1–LeDI-5 was conducted. No obvious inhibitory effects of light signals on the transcription of LeDI-1–LeDI-5 were detected during the first 12 h, but these genes, in particular LeDI-2 and LeDI-4, were suppressed by light signals to some degree during longer culture periods, 12 h to 10 days. These findings suggest that light signals are likely to inhibit the transcription of the shikonin-biosynthetic genes indirectly or under long-term conditions.
Plant Cell, Tissue and Organ Culture – Springer Journals
Published: Jan 13, 2010
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.