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W. Wiktor-Jedrzejczak, C. Szczylik, M. Ratajczak, A. Ahmed (1986)
Congenital murine osteopetrosis inherited with osteosclerotic (oc) gene: hematological characterization.Experimental hematology, 14 9
J. Pollard, J. Hunt, W. Wiktor-Jedrzejczak, E. Stanley (1991)
A pregnancy defect in the osteopetrotic (op/op) mouse demonstrates the requirement for CSF-1 in female fertility.Developmental biology, 148 1
David Hume, Paul Pavli, R. Donahue, Isaiah Fidler (1988)
The effect of human recombinant macrophage colony-stimulating factor (CSF-1) on the murine mononuclear phagocyte system in vivo.Journal of immunology, 141 10
R. Felix, M. Cecchini, W. Hofstetter, P. Elford, A. Stutzer, H. Fleisch (1990)
Rapid publication: Impairment of macrophage colony‐stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op MouseJournal of Bone and Mineral Research, 5
I. Mcniece, T. Bradley, A. Kriegler, G. Hodgson (1986)
Subpopulations of mouse bone marrow high-proliferative-potential colony-forming cells.Experimental hematology, 14 9
Sylvie Gisselbrecht, Brigitte Sola, Serge Fichelson, D. Bordereaux, Pierre Tambourin, Marie Mattei, Dominique Simon, JL Guenet (1989)
The murine M-CSF gene is localized on chromosome 3.Blood, 73 6
S. Bartelmez, T. Bradley, I. Bertoncello, Mochizuki Dy, Tushinski Rj, E. Stanley, Hapel Aj, Young Ig, A. Kriegler, G. Hodgson (1989)
Interleukin 1 plus interleukin 3 plus colony-stimulating factor 1 are essential for clonal proliferation of primitive myeloid bone marrow cells.Experimental hematology, 17 3
(1981)
Hematopoietic stem cell differentiation and its role in osteopetrosis: immunological implications
H. Yoshida, S. Hayashi, T. Kunisada, M. Ogawa, S. Nishikawa, H. Okamura, T. Sudo, L. Shultz, S. Nishikawa (1990)
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneNature, 345
L. Shultz, C. Sidman (1987)
Genetically determined murine models of immunodeficiency.Annual review of immunology, 5
K. Sasaki, G. Matsumura, T. Ito (1983)
Crystalloid inclusion-containing macrophages in the bone marrow and red pulp of the mouse, with particular relation to age, sex and hydrocortisone administration: qualitative and quantitative electron microscopy.Archivum histologicum Japonicum = Nihon soshikigaku kiroku, 46 3
(1990)
Regulation ofmononudear phagocyte proliferation by colony-stimulating factor-1
M. Sc (1987)
Osteopetrosis--multiple pathways for the interception of osteoclast function.Applied pathology, 5
File Description: Published version License: CC BY-NC-SA
Sandy Marks, Priscilla Lane (1976)
Osteopetrosis, a new recessive skeletal mutation on chromosome 12 of the mouse.The Journal of heredity, 67 1
R. Felix, M. Cecchini, H. Fleisch (1990)
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse.Endocrinology, 127 5
J. Austyn, S. Gordon (1981)
F4/80, a monoclonal antibody directed specifically against the mouse macrophageEuropean Journal of Immunology, 11
H. Kodama, A. Yamasaki, Makoto Nose, S. Niida, Y. Ohgame, M. Abe, M. Kumegawa, T. Suda (1991)
Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factorThe Journal of Experimental Medicine, 173
GM-CSF corrects macrophage deficiendes but not osteopetrosis in CSF-1 deficient op/op mouse
W. Wiktor-Jedrzejczak, Ratajczak Mz, A. Ptasznik, K. Sell, A. Ahmed-Ansari, W. Ostertag (1992)
CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages.Experimental hematology, 20 8
(1979)
Research news. Mouse Newslett~
W. Wiktor-Jedrzejczak, E. Urbanowska, S. Aukerman, J. Pollard, E. Stanley, P. Ralph, A. Ansari, K. Sell, M. Szperl (1991)
Correction by CSF-1 of defects in the osteopetrotic op/op mouse suggests local, developmental, and humoral requirements for this growth factor.Experimental hematology, 19 10
S. Marks, (1982)
Morphological evidence of reduced bone resorption in osteopetrotic (op) mice.The American journal of anatomy, 163 2
J. Arnold, S. Ellis, J. Radley, N. Williams (1991)
Compensatory mechanisms in platelet production: the response of Sl/Sld mice to 5-fluorouracil.Experimental hematology, 19 1
W. Wiktor-Jedrzejczak, A. Bartocci, A. Ferrante, A. Ahmed-Ansari, K. Sell, J. Pollard, E. Stanley (1990)
Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.Proceedings of the National Academy of Sciences of the United States of America, 87
E. Stanley, L. Guilbert, R. Tushinski, S. Bartelmez (1983)
CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factorJournal of Cellular Biochemistry, 21
(1988)
Establishment of mouse cell lines which constitutively secrete large quantities of interleukins 2, 3, 4, and 5 using modified cDNA vectors. Fur
M. Mcgarry, C. Stewart (1991)
Murine Eosinophil Granulocytes Bind the Murine Macrophage‐Monocyte Specific Monoclonal Antibody F4/80Journal of Leukocyte Biology, 50
I. Bertoncello (1992)
Status of high proliferative potential colony-forming cells in the hematopoietic stem cell hierarchy.Current topics in microbiology and immunology, 177
W. Wiktor-Jedrzejczak, A. Ahmed, C. Szczylik, R. Skelly (1982)
Hematological characterization of congenital osteopetrosis in op/op mouse. Possible mechanism for abnormal macrophage differentiationThe Journal of Experimental Medicine, 156
(1990)
Brief Definitive Report Stutzer, and H
M. Naito, S. Hayashi, Hisahiro Yoshida, S. Nishikawa, Leonard Shultz, Kiyoshi Takahashi (1991)
Abnormal differentiation of tissue macrophage populations in 'osteopetrosis' (op) mice defective in the production of macrophage colony-stimulating factor.The American journal of pathology, 139 3
Changes in structure, cellularity, hematopoietic progenitor cell and macrophage content, and osteoclast activity were investigated in the hematopoietic organs of the colony-stimulating factor 1(CSF-1)-less osteopetrotic (op/op) mouse. The data indicated that op/op mice undergo an age-related hematopoietic recovery and resolution of osteopetrosis, suggesting that the hematopoietic system has the capacity to use alternative mechanisms to compensate for the absence of an important multifunctional growth factor, CSF-1. In young animals, op/op femurs were heavily infiltrated with bone, and marrow cellularity was significantly reduced. After 6 wk of age, there was an increase in the marrow space available for hematopoiesis. The femoral cavity of op/op mice progressively enlarged, and by 22 wk of age its appearance and marrow cellularity was comparable to that of controls. The percentage of op/op mononuclear phagocytes, defined by F4/80 antigen expression, progressively increased to normal levels by 35 wk of age. There was no difference in the incidence of both primitive and mononuclear phagocyte-committed, CSF-1-responsive progenitor cells in op/op marrow, but their femoral content was significantly reduced in young mice. During the period of reduced hematopoiesis in the marrow of young op/op mice, splenic hematopoietic activity was elevated. This mutant mouse represents a system for the study of the CSF-1-independent regulatory mechanisms involved in hematopoietic regulation.
The Journal of Experimental Medicine – Rockefeller University Press
Published: Jan 1, 1993
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