Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Rosa, K. Jung, M. Perzanowski, E. Kelvin, K. Darling, D. Camann, S. Chillrud, R. Whyatt, P. Kinney, F. Perera, Rachel Miller (2011)
Prenatal exposure to polycyclic aromatic hydrocarbons, environmental tobacco smoke and asthma.Respiratory medicine, 105 6
Hiromi Tadaki, H. Arakawa, Mikio Sugiyama, K. Ozawa, Takahisa Mizuno, H. Mochizuki, K. Tokuyama, A. Morikawa (2009)
Association of cord blood cytokine levels with wheezy infants in the first year of lifePediatric Allergy and Immunology, 20
A. Cuvillo, J. Sastre, J. Montoro, I. Jáuregui, M. Ferrer, I. Dávila, J. Bartra, J. Mullol, A. Valero (2007)
Use of antihistamines in pediatrics.Journal of investigational allergology & clinical immunology, 17 Suppl 2
F. Simons (2004)
Advances in H1-antihistamines.The New England journal of medicine, 351 21
A. Wojdani, L. Alfred (1984)
Alterations in cell-mediated immune functions induced in mouse splenic lymphocytes by polycyclic aromatic hydrocarbons.Cancer research, 44 3
(2005)
Effects of air pollution on chidren's health and development. A review of evidence. WHO European Centre for Environment and Health
H. Bömmel, Min Li-Weber, E. Serfling, A. Duschl (2000)
The environmental pollutant pyrene induces the production of IL-4.The Journal of allergy and clinical immunology, 105 4
N. Beydon, Stephanie Davis, E. Lombardi, Julian Allen, H. Arets, P. Aurora, H. Bisgaard, G. Davis, F. Ducharme, H. Eigen, M. Gappa, C. Gaultier, Per Gustafsson, Graham Hall, Z. Hantos, M.J.R. Healy, M. Jones, B. Klug, Karin Carlsen, Sheila McKenzie, François Marchal, Oscar Mayer, P. Merkus, Mohy Morris, E. Oostveen, J. Pillow, P Seddon, M. Silverman, Peter Sly, J. Stocks, R. Tepper, D. Vilozni, Nicola Wilson (2007)
An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children.American journal of respiratory and critical care medicine, 175 12
F. Perera, D. Tang, R. Whyatt, S. Lederman, W. Jędrychowski (2005)
DNA Damage from Polycyclic Aromatic Hydrocarbons Measured by Benzo[a]pyrene-DNA Adducts in Mothers and Newborns from Northern Manhattan, The World Trade Center Area, Poland, and ChinaCancer Epidemiology Biomarkers & Prevention, 14
W. Jong, E. Kroese, J. Vos, H. Loveren (1999)
Detection of immunotoxicity of benzo[a]pyrene in a subacute toxicity study after oral exposure in rats.Toxicological sciences : an official journal of the Society of Toxicology, 50 2
M. Miller (2010)
AgencyChange: The Magazine of Higher Learning, 42
Ken Ohta, Naomi Yamashita, Makoto Tajima, T. Miyasaka, J. Nakano, M. Nakajima, Akira Ishii, Tadashi Horiuchi, Kenji Mano, Terumasa Miyamoto (1999)
Diesel exhaust particulate induces airway hyperresponsiveness in a murine model: essential role of GM-CSF.The Journal of allergy and clinical immunology, 104 5
Rachel Miller, R. Garfinkel, M. Horton, D. Camann, F. Perera, R. Whyatt, P. Kinney (2004)
Polycyclic aromatic hydrocarbons, environmental tobacco smoke, and respiratory symptoms in an inner-city birth cohort.Chest, 126 4
K. Alexandrov, M. Rojas, Olivier Geneste, Marcel Castegnaro, A. Camus, Stefano Petruzzelli, Carlo Giuntini, Helmut Bartsch (1992)
An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity.Cancer research, 52 22
Annette Peters, Douglas Dockery, Joachim Heinrich, H.-Erich Wichmann (1997)
Medication use modifies the health effects of particulate sulfate air pollution in children with asthma.Environmental Health Perspectives, 105
U. Bucher, L. Reid (1961)
Development of the Intrasegmental Bronchial Tree: the Pattern of Branching and Development of Cartilage at Various Stages of Intra-uterine Life *Thorax, 16
W. Jędrychowski, R. Whyatt, D. Camann, Ulka Bawle, K. Peki, J. Spengler, T. Dumyahn, A. Penar, F. Perera (2003)
Effect of prenatal PAH exposure on birth outcomes and neurocognitive development in a cohort of newborns in Poland. Study design and preliminary ambient data.International journal of occupational medicine and environmental health, 16 1
A. Sydbom, A. Blomberg, S. Parnia, N. Stenfors, T. Sandström, S. Dahlén (2001)
Health effects of diesel exhaust emissions.The European respiratory journal, 17 4
S. Baek, R. Field, M. Goldstone, P. Kirk, J. Lester, R. Perry (1991)
A review of atmospheric polycyclic aromatic hydrocarbons: Sources, fate and behaviorWater, Air, and Soil Pollution, 60
A. Lowe, J. Carlin, C. Bennett, C. Hosking, M. Abramson, D. Hill, S. Dharmage (2007)
Association of cord blood cytokine production with wheezy infants in the first year of lifeWorld Allergy Organization Journal, &NA;
G. Canonica, M. Blaiss (2011)
Antihistaminic, Anti-Inflammatory, and Antiallergic Properties of the Nonsedating Second-Generation Antihistamine Desloratadine: A Review of the EvidenceThe World Allergy Organization Journal, 4
Long-Path Fourier (1999)
Compendium of Methods for the Determination of Toxic Organic Compounds in Ambient Air
M. Emanuel (1999)
Histamine and the antiallergic antihistamines: a history of their discoveriesClinical & Experimental Allergy, 29
B. Schoket (1999)
DNA damage in humans exposed to environmental and dietary polycyclic aromatic hydrocarbons.Mutation research, 424 1-2
H. Bömmel, M. Haake, Petra Luft, J. Horejs-Hoeck, H. Hein, J. Bartels, C. Schauer, U. Pöschl, M. Kracht, A. Duschl (2003)
The diesel exhaust component pyrene induces expression of IL-8 but not of eotaxin.International immunopharmacology, 3 10-11
R. Whyatt, R. Santella, W. Jędrychowski, S. Garte, Doug Bell, R. Ottman, Alicja Gladek-Yarborough, G. Cosma, T. Young, T. Cooper, M. Randall, D. Manchester, F. Perera (1998)
Relationship between ambient air pollution and DNA damage in Polish mothers and newborns.Environmental Health Perspectives, 106
H. Hattemer-Frey, C. Travis (1991)
Benzo-a-Pyrene: Environmental Partitioning and Human ExposureToxicology and Industrial Health, 7
S. Salvi, C. Nordenhall, A. Blomberg, B. Rudell, J. Pourazar, F. Kelly, S. Wilson, T. Sandström, S. Holgate, A. Frew (2000)
Acute exposure to diesel exhaust increases IL-8 and GRO-alpha production in healthy human airways.American journal of respiratory and critical care medicine, 161 2 Pt 1
J. Hardin, Joseph Hilbe (2001)
Generalized Linear Models and Extensions
M. Knize, C. Salmon, P. Pais, J. Felton (1999)
Food heating and the formation of heterocyclic aromatic amine and polycyclic aromatic hydrocarbon mutagens/carcinogens.Advances in experimental medicine and biology, 459
S. Fujieda, D. Díaz-Sánchez, A. Saxon (1998)
Combined nasal challenge with diesel exhaust particles and allergen induces In vivo IgE isotype switching.American journal of respiratory cell and molecular biology, 19 3
Y. Heo, A. Saxon, O. Hankinson (2001)
Effect of diesel exhaust particles and their components on the allergen-specific IgE and IgG1 response in mice.Toxicology, 159 3
Y. Zhao, P. Leung, K. Woo, G. Chen, Y. Wong, S. Liu, C. Hasselt (2004)
Inhibitory effects of budesonide, desloratadine and dexamethasone on cytokine release from human mast cell line (HMC-1)Inflammation Research, 53
W. Jędrychowski, F. Perera, U. Maugeri, D. Mrożek-Budzyn, E. Mróz, M. Klimaszewska-Rembiasz, E. Flak, Susan Edwards, J. Spengler, R. Jacek, A. Sowa (2010)
Intrauterine exposure to polycyclic aromatic hydrocarbons, fine particulate matter and early wheeze. Prospective birth cohort study in 4‐year oldsPediatric Allergy and Immunology, 21
A. Saxon, D. Díaz-Sánchez (2000)
Diesel exhaust as a model xenobiotic in allergic inflammation.Immunopharmacology, 48 3
F. Estelle, R. Simons (2014)
Advances in H 1 -Antihistamines
F. Simons (2002)
H1-antihistamines in children.Clinical allergy and immunology, 17
A. Hubbard, J. Ahern, N. Fleischer, M. Laan, Sheri Lippman, N. Jewell, T. Bruckner, W. Satariano (2010)
To GEE or Not to GEE: Comparing Population Average and Mixed Models for Estimating the Associations Between Neighborhood Risk Factors and HealthEpidemiology, 21
G. Devouassoux, A. Saxon, D. Metcalfe, C. Prussin, M. Colomb, C. Brambilla, D. Díaz-Sánchez (2002)
Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils.The Journal of allergy and clinical immunology, 109 5
Zedeck Ms (1980)
Polycyclic aromatic hydrocarbons: a review.Journal of environmental pathology and toxicology, 3 5-6
(2005)
of air pollution on chidren’s health and development
J. Hardin, Joseph Hilbe (2012)
Generalized Linear Models and Extensions, Third Edition
(2007)
American Thoracic Society Documents An Official American Thoracic Society/European Respiratory Society Statement: Pulmonary Function Testing in Preschool Children
J. Mullol, J. Roca‐Ferrer, I. Alobid, L. Pujols, A. Valero, A. Xaubet, M. Bernal-Sprekelsen, César Picado (2006)
Effect of desloratadine on epithelial cell granulocyte‐macrophage colony‐stimulating factor secretion and eosinophil survivalClinical & Experimental Allergy, 36
D. Parton, R. Snow, W. Seibert (1964)
Review of the Evidence.Science, 146 3651
S. Molet, P. Gosset, P. Lassalle, W. Czarlewski, A. Tonnel (1997)
Inhibitory activity of loratadine and descarboxyethoxyloratadine on histamine‐induced activation of endothelial cellsClinical & Experimental Allergy, 27
(2003)
Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages
A. Spira-Cohen, Lung-Chi Chen, M. Kendall, R. Lall, G. Thurston (2011)
Personal Exposures to Traffic-Related Air Pollution and Acute Respiratory Health among Bronx Schoolchildren with AsthmaEnvironmental Health Perspectives, 119
H. Takano, T. Yoshikawa, T. Ichinose, Y. Miyabara, K. Imaoka, M. Sagai (1997)
Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice.American journal of respiratory and critical care medicine, 156 1
Summary The main purpose of the present study was to test the hypothesis that the depressed lung growth attributable to prenatal exposure to polycyclic aromatic hydrocarbons (PAH) may be modified by the intake of antihistamine medications. Individual prenatal PAH exposure was assessed by personal air monitoring in 176 children who were followed over nine years, in the course of which outdoor residential air monitoring, allergic skin tests for indoor allergens, lung function tests (FVC, FEV1, FEV05, and FEF25‐75) were performed. The analysis with the General Estimated Equation (GEE) showed no association between prenatal PAH exposure and lung function in the group of children who were reported to be antihistamine users. However, in the group of antihistamine non‐users all lung function tests except for FEF25‐75 were significantly and inversely associated with prenatal airborne PAH exposure. The results of the study suggest that the intake of antihistamine medications in early childhood may inhibit the negative effect of fetal PAH exposure on lung growth and provides additional indirect evidence for the hypothesis that lung alterations in young children resulting from PAH exposure may be caused by the allergic inflammation within lung. Pediatr Pulmonol. 2015; 50:469–478. © 2014 Wiley Periodicals, Inc.
Pediatric Pulmonology – Wiley
Published: May 1, 2015
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.