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H. Schaefer, T. Redelmeier (1996)
Skin Barrier: Principles of Percutaneous Absorption
B. Aungst, J. Blake, M. Hussain (1990)
Contributions of Drug Solubilization, Partitioning, Barrier Disruption, and Solvent Permeation to the Enhancement of Skin Permeation of Various Compounds with Fatty Acids and AminesPharmaceutical Research, 7
Y. Takeuchi, H. Yasukawa, Y. Yamaoka, K. Taguchi, S. Fukushima, Y. Shimonaka, H. Nishinaga, Y. Morimoto (1995)
Behavior of propylene glycol (PG) in dermis after treatment of rat intact skin surface with fatty acids, fatty amines or azone dissolved in PG.Biological & pharmaceutical bulletin, 18 2
C. Günther (1990)
In vitro-und in vivo-Untersuchungen zur perkutanen Resorption von Estrogenen und Gestagenen als Grundlage für die Entwicklung eines transdermalen therapeutischen Systems
P. Wotton, B. Møllgaard, J. Hadgraft, A. Hoelgaard (1985)
Vehicle effect on topical drug delivery. III. Effect of Azone on the cutaneous permeation of metronidazole and propylene glycolInternational Journal of Pharmaceutics, 24
J. Hadgraft (1996)
Recent developments in topical and transdermal deliveryEur. J. Drug. Metab. Pharmacokinet., 21
S. Kitagawa, A. Hosokai, Yoshiyuki Kaseda, Nobuya Yamamoto, Yoh Kaneko, E. Matsuoka (1998)
Permeability of benzoic acid derivatives in excised guinea pig dorsal skin and effects of l-mentholInternational Journal of Pharmaceutics, 161
P. Cornwell, B. Barry, J. Bouwstra, G. Gooris (1996)
Modes of action of terpene penetration enhancers in human skin; Differential scanning calorimetry, small-angle X-ray diffraction and enhancer uptake studiesInternational Journal of Pharmaceutics, 127
B. Bendas, Ulrike Schmalfuβ, R. Neubert (1995)
Influence of propylene glycol as cosolvent on mechanisms of drug transport from hydrogelsInternational Journal of Pharmaceutics, 116
K. Cumming, A. Winfield (1994)
In vitro evaluation of a series of sodium carboxylates as dermal penetration enhancersInternational Journal of Pharmaceutics, 108
T. Ogiso, Masako Shintani (1990)
Mechanism for the enhancement effect of fatty acids on the percutaneous absorption of propranolol.Journal of pharmaceutical sciences, 79 12
H. Tanojo, J. Bouwstra, H. Junginger, H. Boddé (2004)
In Vitro Human Skin Barrier Modulation by Fatty Acids: Skin Permeation and Thermal Analysis StudiesPharmaceutical Research, 14
C. Leopold, B. Lippold (1995)
An Attempt to Clarify the Mechanism of the Penetration Enhancing Effects of Lipophilic Vehicles with Differential Scanning Calorimetry (DSC) *Journal of Pharmacy and Pharmacology, 47
R. Hinz, C. Lorence, Connie Hodson, Corwin Hansch, Larry Hall, Richard Guy (1991)
Percutaneous penetration of para-substituted phenols in vitro.Fundamental and applied toxicology : official journal of the Society of Toxicology, 17 3
J. Hadgraft (1999)
Dermal and transdermal drug designInternational Journal of Pharmaceutical Medicine, 13
M. Dittgen (1997)
Pharmazeutische Technologie: Moderne Arzneiformen
Susana Santoyo, P. Ygartua (2000)
Effect of skin pretreatment with fatty acids on percutaneous absorption and skin retention of piroxicam after its topical application.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 50 2
B. Barry (1991)
Lipid-Protein-Partitioning theory of skin penetration enhancementJournal of Controlled Release, 15
A. Pardo, Y. Shiri, S. Cohen (1990)
Percutaneous absorption of physostigmine: optimization of delivery from a binary solvent by thermodynamic control.Journal of pharmaceutical sciences, 79 7
Y. Komata, A. Kaneko, T. Fujie (1995)
Accumulation of lauric acid in skin as an enhancer for the percutaneous absorption of thiamine disulfide.Biological & pharmaceutical bulletin, 18 5
B. Barry (1983)
Dermatological Formulations: Percutaneous Absorption
Y. W. Chien (1987)
Transdermal controlled systemic medications
Samir Mitragotri, David Edwards, David Edwards, D. Blankschtein, Robert Langer (1995)
A mechanistic study of ultrasonically-enhanced transdermal drug delivery.Journal of pharmaceutical sciences, 84 6
R. L. Elder (1987)
palmitic acid, myristic acid and stearic acidJ.Am.Coll.Toxicol., 6
P. Stott, Adrian Williams, B. Barry (2001)
Mechanistic study into the enhanced transdermal permeation of a model beta-blocker, propranolol, by fatty acids: a melting point depression effect.International journal of pharmaceutics, 219 1-2
T. Suhonen, J. Bouwstra, A. Urtti (1999)
Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations.Journal of controlled release : official journal of the Controlled Release Society, 59 2
Han-Joon Oh, Yu-Kyoung Oh, Chong-Kook Kim (2001)
Effects of vehicles and enhancers on transdermal delivery of melatonin.International journal of pharmaceutics, 212 1
S. Jiang, Y. Kim, Seung Lee (1998)
The Ultrastructural Changes of Stratum Corneum Lipids after Application of Oleic Acid in Propylene GlycolAnnals of Dermatology, 10
Purpose. Highly lipophilic basic drugs, the antiestrogens AE 1 (log P = 5.82) and AE 2 (log P = 7.8) shall be delivered transdermally.
Pharmaceutical Research – Springer Journals
Published: Oct 10, 2004
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