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M. Söderlund, R. Essen, J. Haapasaari, U. Kiistala, O. Kiviluoto, K. Hedman (1997)
Persistence of parvovirus B19 DNA in synovial membranes of young patients with and without chronic arthropathyThe Lancet, 349
Frank Foto, K. Saag, Laura Scharosch, E. Howard, S. Naides (1993)
Parvovirus B19-specific DNA in bone marrow from B19 arthropathy patients: evidence for B19 virus persistence.The Journal of infectious diseases, 167 3
HEIDI Bauer, Y. Ting, Catherine Greer, J. Chambers, CATHY Tashiro, J. Chimera, A. Reingold, M. Manos (1991)
Genital human papillomavirus infection in female university students as determined by a PCR‐based methodInternational Journal of Gynecology & Obstetrics, 36
Bauer Bauer, Ting Ting, Greer Greer, Chambers Chambers, Tashiro Tashiro, Chimera Chimera, Reingold Reingold, Manos Manos (1991)
Genital human papillomavirus infection in female university students as determined by a PCR‐based methodJournal of the American Medical Association, 265
P. Cassinotti, S. Bas, G. Siegl, T. Vischer (1995)
Association between human parvovirus B19 infection and arthritis.Annals of the Rheumatic Diseases, 54
H. Faden, G. Gary, Larry Anderson (1992)
Chronic parvovirus infection in a presumably immunologically healthy woman.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 15 4
L. Coulombel, F. Morinet, F. Miélot, G. Tchernia, A. Knisely, P. Shlossman, J. Davidson, B. Gibson, A. Gibson, T. Evans (1989)
PARVOVIRUS INFECTION, LEUKAEMIA, AND IMMUNODEFICIENCYThe Lancet, 333
S. Nikkari, R. Luukkainen, Timo Mott6nen, O. Meurman, P. Hannonen, Mikael Skumik, P. Toivanen (1994)
Does parvovirus B19 have a role in rheumatoid arthritis?Annals of the Rheumatic Diseases, 53
Cassinotti Cassinotti (1995)
Human parvovirus B19 infections and their diagnosisAlpe Adria Microbiology Journal, 4
J. Kerr, M. Curran, J. Moore, P. Coyle, W. Fergusson (1995)
Persistent parvovirus B19 infectionThe Lancet, 345
R. Shade, M. Blundell, S. Cotmore, P. Tattersall, C. Astell (1986)
Nucleotide sequence and genome organization of human parvovirus B19 isolated from the serum of a child during aplastic crisisJournal of Virology, 58
J. Kerr, J. Cartron, M. Curran, J. Moore, J. Elliott, R. Mollan (1995)
A study of the role of parvovirus B19 in rheumatoid arthritis.British journal of rheumatology, 34 9
E. Ager, T. Chin, J. Poland (1966)
Epidemic erythema infectiosum.The New England journal of medicine, 275 24
D. Reid, T. Brown, T. Reid, J. Rennie, C. Eastmond (1985)
HUMAN PARVOVIRUS-ASSOCIATED ARTHRITIS: A CLINICAL AND LABORATORY DESCRIPTIONThe Lancet, 325
P. Branigan, H. Gérard, A. Hudson, H. Schumacher, J. Pando (1996)
Comparison of synovial tissue and synovial fluid as the source of nucleic acids for detection of Chlamydia trachomatis by polymerase chain reaction.Arthritis and rheumatism, 39 10
S. Nikkari, A. Roivainen, P. Hannonen, T. Möttönen, R. Luukkainen, T. Yli-Jama, P. Toivanen (1995)
Persistence of parvovirus B19 in synovial fluid and bone marrow.Annals of the Rheumatic Diseases, 54
N. Miki, J. Chantler (1992)
Non-permissiveness of synovial membrane cells to human parvovirus B19 in vitro.The Journal of general virology, 73 ( Pt 6)
J. Nocton, L. Miller, L. Tucker, J. Schaller (1993)
Human parvovirus B19-associatedarthritis in childrenThe Journal of Pediatrics, 122
D. White, D. White, P. Mortimer, P. Mortimer, D. Blake, D. Blake, A. Woolf, A. Woolf, B. Cohen, B. Cohen, P. Bacon, P. Bacon (1985)
HUMAN PARVOVIRUS ARTHROPATHYThe Lancet, 325
M. Anderson, S. Jones, S. Fisher-Hoch, E. Lewis, S. Hall, C. Bartlett, B. Cohen, P. Mortimer, M. Pereira (1983)
HUMAN PARVOVIRUS, THE CAUSE OF ERYTHEMA INFECTIOSUM (FIFTH DISEASE)?The Lancet, 321
P. Cassinotti, G. Burtonboy, M. Fopp, G. Siegl (1997)
Evidence for persistence of human parvovirus B19 DNA in bone marrowJournal of Medical Virology, 53
A. Jawad (1993)
Persistent arthritis after human parvovirus B19 infectionThe Lancet, 341
Kandolf Kandolf, Kirschner Kirschner, Hofschneider Hofschneider, Vischer Vischer (1989)
Detection of parvovirus in a patient with “reactive arthritis” by in situ hybridizationClinical Rheumatology, 8
P. Cassinotti, M. Weitz, G. Siegl (1993)
Human parvovirus B19 infections: Routine diagnosis by a new nested polymerase chain reaction assayJournal of Medical Virology, 40
A. Woolf, G. Campion, Alice Chishick, S. Wise, B. Cohen, P. Klouda, Owen Caul, P. Dieppe (1989)
Clinical manifestations of human parvovirus B19 in adults.Archives of internal medicine, 149 5
B. Dijkmans, A. Elsacker-Niele, M. Salimans, G. Albada-Kuipers, E. Vries, H. Weiland (1988)
Human parvovirus B19 DNA in synovial fluid.Arthritis and rheumatism, 31 2
Takeshi Sasaki, C. Murai, T. Muryoi, Yuichi Takahashi, Y. Munakata, K. Sugamura, Keishi Abe (1995)
Persistent infection of human parvovirus B19 in a normal subjectThe Lancet, 346
Acute rheumatologic symptoms are frequently associated with human parvovirus B19 (B19) infections. A nested PCR (nPCR) assay was used to test for the presence of parvovirus B19 DNA in synovial fluid and/or synovial membrane specimens obtained from a total of 90 patients with arthritis of unknown origin. Whereas only one out of 73 synovial fluid samples were found positive, 15 (16.7%) out of 90 patients had parvovirus B19 DNA in the synovium. B19 virus DNA was detected in nine bone marrow aspirates subsequently obtained from these 15 patients (60%). Whereas each one of the 15 corresponding blood samples contained anti‐B19 IgG antibody, none contained anti‐B19 IgM antibody and only one was positive for B19 virus DNA. The blood and synovial fluid samples that contained B19 virus DNA were obtained from the same patient, who also had B19 DNA in synovium and bone marrow. For one patient, two distinct synovial membrane specimens collected 10 months apart tested positive for B19 virus DNA. Parvovirus B19 DNA was also detected in synovial tissue of one out of nine nonarthritic patients serving as control group, who also had anti‐B19 IgG circulating antibody. These data illustrate that human parvovirus B19 may persist in bone marrow and synovial tissues of patients with arthritis of unknown origin. In contrast, persistence of B19 virus DNA in synovial fluid is rare. The significance of parvovirus B19 DNA in synovium of healthy patients has to be established. J. Med. Virol. 56:199–204, 1998. © 1998 Wiley‐Liss, Inc.
Journal of Medical Virology – Wiley
Published: Nov 1, 1998
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