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Human Posttransfusion Graft‐versus‐Host Disease

Human Posttransfusion Graft‐versus‐Host Disease Abstract. Graft‐versus‐host disease (GVDH) follows blood product transfusions in patients with deficient cell‐mediated immunity. The rate of mortality in this adverse effect of blood transfusions is between 90 and 100%. The historical; clinical and pathologic; and mechanism of acute and chronic GVHD are presented. The patients at risk, the clinical and pathologic features of posttransfusion GVDH have been presented in hopes that, with increased awareness of this usually fatal complication, clinicians and transfusion therapists may more intelligently advise and select patients who may need lymphocyte‐poor or irradiated blood products and may recognize the syndrome earlier. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Vox Sanguinis Wiley

Human Posttransfusion Graft‐versus‐Host Disease

Vox Sanguinis , Volume 45 (6) – Dec 1, 1983

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References (108)

Publisher
Wiley
Copyright
© 1983 S. Karger AG, Basel
ISSN
0042-9007
eISSN
1423-0410
DOI
10.1111/j.1423-0410.1983.tb01937.x
Publisher site
See Article on Publisher Site

Abstract

Abstract. Graft‐versus‐host disease (GVDH) follows blood product transfusions in patients with deficient cell‐mediated immunity. The rate of mortality in this adverse effect of blood transfusions is between 90 and 100%. The historical; clinical and pathologic; and mechanism of acute and chronic GVHD are presented. The patients at risk, the clinical and pathologic features of posttransfusion GVDH have been presented in hopes that, with increased awareness of this usually fatal complication, clinicians and transfusion therapists may more intelligently advise and select patients who may need lymphocyte‐poor or irradiated blood products and may recognize the syndrome earlier.

Journal

Vox SanguinisWiley

Published: Dec 1, 1983

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