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Seroma formation following axillary dissection for breast cancer: Risk factors and lack of influence of bovine thrombinJournal of Surgical Oncology, 64
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Prolonged `seroma' formations have been reported as the commonest complication following breast cancer surgery [1±5] with incidence varying from 15 to 85%. In addition to causing inconvenience, repeated seroma formation requires frequent hospital visits for needle aspiration or sometimes prolonged hospitalization. Repeated aspirations (at times continue for months), which add to the cost of treatment, may lead to infection and sometimes delay adjuvant treatment. This complication has worried clinicians so much that they have been compelled to think about the alternatives of axillary dissection, for example, sentinel node biopsy. We at our center never faced this complication in our clinical practice and we have hardly aspirated seroma following removal of axillary drain possibly because of our different technique of axillary compression (Fig. 1) and delayed drain removal. I had presumed that world-over this practice was being followed until I saw the literature. I don't think I need the support of randomized controlled trial to prove my point. Various interventions have been attempted to reduce the seroma formation (Table I). Only two authors [4,8] appear to have achieved succsess in reducing seroma formation. Oerteli et al [9] reported reduction in seroma formation by peri-operative and postoperative adminisTABLE I. Summary
Journal of Surgical Oncology – Wiley
Published: Dec 1, 2001
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