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Factors influencing triacylglycerol delivery into mesenteric lymph

Factors influencing triacylglycerol delivery into mesenteric lymph ~. M,,II,A. AND M. A.Cox.F’actors influencing triucylglycerol delivery into mesenteric lymph. Am. J. Physiol. 249 (Gastrointest. Liver Physiol. 12): G642-G648, 1985.-The of triacylglycerol (TG) in mesenteric lymph was studied in rats with duodenal and mesenteric cannulas with or without bile fistulas. Rats were infused with 135 pmol glycerol trioleate (TO) for 4 h, followed by 5 h of NaCl infusion. Rats with intact fistulas prefed 20% corn oil had nearly twice the maximum output of TG in lymph as controls. Decay from peak values was zero order for controls and indeterminate for rats prefed corn oil. In rats with bile fistulas, less TG was ed in lymph than in those in which 2 mM phosphatidylcholine (PC) was added to the infusate. The decay from maximum values was zero order for controls and first order for rats infused with PC and TO. Recovery of infused [3H]glycerol trioleate in controls was 43% and increased to 68% on inclusion of PC in the infusate. We conclude that 1) in chow-fed rats lymph TG delivery rates were well below infusion rates, suggesting alternate TG routes, 2) TG was improved by supplementing the i&sate with PC or prefeeding with 20% TG in chow, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png AJP - Gastrointestinal and Liver Physiology The American Physiological Society

Factors influencing triacylglycerol delivery into mesenteric lymph

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Publisher
The American Physiological Society
Copyright
Copyright © 1985 the American Physiological Society
ISSN
0193-1857
eISSN
1522-1547
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Abstract

~. M,,II,A. AND M. A.Cox.F’actors influencing triucylglycerol delivery into mesenteric lymph. Am. J. Physiol. 249 (Gastrointest. Liver Physiol. 12): G642-G648, 1985.-The of triacylglycerol (TG) in mesenteric lymph was studied in rats with duodenal and mesenteric cannulas with or without bile fistulas. Rats were infused with 135 pmol glycerol trioleate (TO) for 4 h, followed by 5 h of NaCl infusion. Rats with intact fistulas prefed 20% corn oil had nearly twice the maximum output of TG in lymph as controls. Decay from peak values was zero order for controls and indeterminate for rats prefed corn oil. In rats with bile fistulas, less TG was ed in lymph than in those in which 2 mM phosphatidylcholine (PC) was added to the infusate. The decay from maximum values was zero order for controls and first order for rats infused with PC and TO. Recovery of infused [3H]glycerol trioleate in controls was 43% and increased to 68% on inclusion of PC in the infusate. We conclude that 1) in chow-fed rats lymph TG delivery rates were well below infusion rates, suggesting alternate TG routes, 2) TG was improved by supplementing the i&sate with PC or prefeeding with 20% TG in chow,

Journal

AJP - Gastrointestinal and Liver Physiology – The American Physiological Society

Published: Nov 1, 1985

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