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Metabolic response of equine muscle to intermittent maximal exercise

Metabolic response of equine muscle to intermittent maximal exercise lactate; metabolism; inosine 5’-monophosphate horse; adenosine 5’-triphosphate; PREVIOUS STUDIES IN THE RACEHORSE have shown that during intense exercise the lactate content both blood (36, 37) (24) is considerably increased to amounts greater than have been reported to occur in humans over comparable running distances. In addition, studies (l&37) have also shown an increase with exercise in the blood level uric acid, suggesting a significant breakdown in ATP, since the former is an end product purine catabolism in the body. It is known that in humans other species intense exercise can result in an appreciable decrease in ATP; the breakdown the nucleotide normally stopping at the level inosine 5’-monophosphate (IMP) (31). The present study is a continuation these earlier ones was intended to investigate further the changes in in to maximal exercise during recovery, with particular emphasis to the fate ATP other purine nucleotides. MATERIALSMETHODS program that was scheduled to last 8 wk. The training program was held over 2 mo during which the horses were regularly walked or trotted. During the second month the schedule included 2 days wk-’ cantering galloping. During training, however, two the animals ~becamelame leaving only four that completed the program. These four horses http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Applied Physiology The American Physiological Society

Metabolic response of equine muscle to intermittent maximal exercise

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Publisher
The American Physiological Society
Copyright
Copyright © 1985 the American Physiological Society
ISSN
8750-7587
eISSN
1522-1601
Publisher site
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Abstract

lactate; metabolism; inosine 5’-monophosphate horse; adenosine 5’-triphosphate; PREVIOUS STUDIES IN THE RACEHORSE have shown that during intense exercise the lactate content both blood (36, 37) (24) is considerably increased to amounts greater than have been reported to occur in humans over comparable running distances. In addition, studies (l&37) have also shown an increase with exercise in the blood level uric acid, suggesting a significant breakdown in ATP, since the former is an end product purine catabolism in the body. It is known that in humans other species intense exercise can result in an appreciable decrease in ATP; the breakdown the nucleotide normally stopping at the level inosine 5’-monophosphate (IMP) (31). The present study is a continuation these earlier ones was intended to investigate further the changes in in to maximal exercise during recovery, with particular emphasis to the fate ATP other purine nucleotides. MATERIALSMETHODS program that was scheduled to last 8 wk. The training program was held over 2 mo during which the horses were regularly walked or trotted. During the second month the schedule included 2 days wk-’ cantering galloping. During training, however, two the animals ~becamelame leaving only four that completed the program. These four horses

Journal

Journal of Applied Physiology – The American Physiological Society

Published: May 1, 1985

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