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References (103)
-
P. Sharp, Steven Hardy, R. Padgett (1987)
Splicing of messenger RNA precursors.Science, 235 4790
-
M. Karin (1989)
Complexities of gene regulation by cAMP.Trends in genetics : TIG, 5 3
-
991) Effect of ciliary neurotrophic factor(CNTF) on motorneuron survival -
B. Friedman, S. Scherer, J. Rudge, M. Helgren, D. Morrisey, J. McClain, Da-yuan Wang, S. Wiegand, M. Furth, R. Lindsay, N. Ip (1992)
Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivoNeuron, 9
-
M. Manthorpe, S. Skaper, L. Williams, S. Varon (1986)
Purification of adult rat sciatic nerve ciliary neuronotrophic factorBrain Research, 367
-
M. Kozak (1987)
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.Nucleic acids research, 15 20
-
A. Giangrande, C. Mettling, M. Martin, C. Ruiz, G. Richards (1989)
Drosophila Sgs3 TATA: effects of point mutations on expression in vivo and protein binding in vitro with staged nuclear extracts.The EMBO Journal, 8
-
D. Masquilier, Paolo Sassone-Corsi (1992)
Transcriptional cross-talk: nuclear factors CREM and CREB bind to AP-1 sites and inhibit activation by Jun.The Journal of biological chemistry, 267 31
-
(1993)
Injuryinduced regulation of ciliary neurotrophic factor mRNA in the adult rat -
(1989)
Molecular Cloning , 2nd edition -
A. Logan, S. Frautschy, A. González, A. Baird (1992)
A time course for the focal elevation of synthesis of basic fibroblast growth factor and one of its high-affinity receptors (flg) following a localized cortical brain injury, 12
-
S. Frautschy, P. Walicke, A. Baird (1991)
Localization of basic fibroblast growth factor and its mRNA after CNS injuryBrain Research, 553
-
Andrew Lam, Forrest Fuller, Judith Miller, Jean Kloss, M. Manthorpe, Silvio Varon, Barbara Cordell (1991)
Sequence and structural organization of the human gene encoding ciliary neurotrophic factor.Gene, 102 2
-
G. Wilkin, D. Marriott, A. Cholewinski (1990)
Astrocyte heterogeneityTrends in Neurosciences, 13
-
A. Laurenza, E. Sutkowski, K. Seamon (1989)
Forskolin: a specific stimulator of adenylyl cyclase or a diterpene with multiple sites of action?Trends in pharmacological sciences, 10 11
-
Y. Arakawa, M. Sendtner, H. Thoenen (1990)
Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines, 10
-
H. Wekerle, C. Linington, H. Lassmann, R. Meyermann (1986)
Cellular immune reactivity within the CNSTrends in Neurosciences, 9
-
(1978)
Fine structure genetic analysis of a J 3globin promoter -
(1992)
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuropathy -
M. Sendtner, H. Schmalbruch, K. Stöckli, P. Carroll, G. Kreutzberg, H. Thoenen (1992)
Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathyNature, 358
-
K. Stöckli, F. Lottspeich, M. Sendtner, P. Masiakowski, P. Carroll, R. Götz, D. Lindholm, H. Thoenen (1989)
Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factorNature, 342
-
Luis Agulió, F. Picatoste, Agustina Garcı́a (1990)
Histamine Stimulation of Cyclic AMP Accumulation in Astrocyte‐Enriched and Neuronal Primary Cultures from Rat BrainJournal of Neurochemistry, 55
-
Atkinson Atkinson, Minneman Minneman (1991)
Multiple adrenergic subtypes controlling cyclic AMP formation: Comparison of brain slices and primary neuronal and glial cellsJ. Neurochem., 56
-
(1990)
Current Protocols in Molecular Biology -
(1992)
Ciliary neurotrophic factor prevents -
P. Lazar, M. Reddington, W. Streit, G. Raivich, W. KreutzbergGeorg (1991)
The action of calcitonin gene-related peptide on astrocyte morphology and cyclic AMP accumulation in astrocyte cultures from neonatal rat brainNeuroscience Letters, 130
-
(1986)
Splicing of RNA precursors -
J. Rudge, R. Alderson, E. Pasnikowski, J. McClain, N. Ip, R. Lindsay (1992)
Expression of Ciliary Neurotrophic Factor and the Neurotrophins – Nerve Growth Factor, Brain‐Derived Neurotrophic Factor and Neurotrophin 3—in Cultured Rat Hippocampal AstrocytesEuropean Journal of Neuroscience, 4
-
Ann Logan, A. Baird (1996)
Fibroblast growth factors, 1
-
(1989)
The " initiator " as a transcriptional control element -
O. Kempski, B. Wróblewska, M. Spatz (1987)
Effects of forskolin on growth and morphology of cultured glial and cerebrovascular endothelial and smooth muscle cellsInternational Journal of Developmental Neuroscience, 5
-
N. Seniuk, M. Altares, R. Dunn, P. Richardson (1992)
Decreased synthesis of ciliary neurotrophic factor in degenerating peripheral nervesBrain Research, 572
-
(1993)
Injuryinduced regulation of ciliary neurotrophic factor mRNA in the adult rat brain -
P. Chomczyński, N. Sacchi (1987)
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.Analytical biochemistry, 162 1
-
H. Herschman (1991)
Primary response genes induced by growth factors and tumor promoters.Annual review of biochemistry, 60
-
B. Pettmann, M. Weibel, M. Sensenbrenner, G. Labourdette (1985)
Purification of two astroglial growth factors from bovine brainFEBS Letters, 189
-
S. Saadat, M. Sendtner, H. Rohrer (1989)
Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in cultureThe Journal of Cell Biology, 108
-
M. Sendtner, Y. Arakawa, K. Stöckli, G. Kreutzberg, H. Thoenen (1991)
Effect of ciliary neurotrophic factor (CNTF) on motoneuron survivalJournal of Cell Science, 1991
-
P. Delli-Bovi, A. Curatola, K. Newman, Y. Sato, D. Moscatelli, R. Hewick, D. Rifkin, C. Basilico (1988)
Processing, secretion, and biological properties of a novel growth factor of the fibroblast growth factor family with oncogenic potentialMolecular and Cellular Biology, 8
-
(1990)
Histamine stimulation of cAMP accumulation in astrocyte-enriched and neuronal primary cultures from rat -
V. Yong, Robert Moumdjian, Fiona Yong, T. Ruijs, Mark Freedman, Neil Cashman, J. Antel (1991)
Gamma-interferon promotes proliferation of adult human astrocytes in vitro and reactive gliosis in the adult mouse brain in vivo.Proceedings of the National Academy of Sciences of the United States of America, 88
-
I. Matsuoka, M. Meyer, H. Thoenen (1991)
Cell-type-specific regulation of nerve growth factor (NGF) synthesis in non-neuronal cells: comparison of Schwann cells with other cell types, 11
-
S. Finklestein, P. Apostolides, C. Caday, James Prosser, M. Philips, M. Klagsbrun (1988)
Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain woundsBrain Research, 460
-
K. Stöckli, L Lillien, M. Näher-Noé, G. Breitfeld, R. Hughes, M Raff, H. Thoenen, M. Sendtner (1991)
Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brainThe Journal of Cell Biology, 115
-
L. Lillien, M. Raff (1990)
Differentiation signals in the CNS: Type-2 astrocyte development in vitro as a model systemNeuron, 5
-
Friedman Friedman, Scherer Scherer, Rudge Rudge, Helgren Helgren, Morrisey Morrisey, McClain McClain, Wang Wang, Wiegand Wiegand, Furth Furth, Lindsay Lindsay, Ip Ip (1992)
Regulation of ciliary neurotrophic factor in myelin‐related Schwann cells in vivoNeuron, 9
-
B. Atkinson, K. Minneman (1991)
Multiple Adrenergic Receptor Subtypes Controlling Cyclic AMP Formation: Comparison of Brain Slices and Primary Neuronal and Glial CulturesJournal of Neurochemistry, 56
-
K. Seamon, W. Padgett, J. Daly (1981)
Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.Proceedings of the National Academy of Sciences of the United States of America, 78 6
-
N. Samuel, K. Jessen, J. Grange, R. Mirsky (1987)
Gamma interferon, but notMycobacterium leprae, induces major histocompatibility class II antigens on cultured rat Schwann cellsJournal of Neurocytology, 16
-
R. Pollenz, K. McCarthy (1986)
Analysis of Cyclic AMP‐Dependent Changes in Intermediate Filament Protein Phosphorylation and Cell Morphology in Cultured AstrogliaJournal of Neurochemistry, 47
-
T. Olsson (1992)
Cytokines in neuroinflammatory disease: role of myelin autoreactive T cell production of interferon-gammaJournal of Neuroimmunology, 40
-
B. Pugh, R. Tjian (1991)
Transcription from a TATA-less promoter requires a multisubunit TFIID complex.Genes & development, 5 11
-
F. Besnard, F. Perraud, M. Sensenbrenner, G. Labourdette (1987)
Platelet-derived growth factor is a mitogen for glial but not for neuronal rat brain cells in vitroNeuroscience Letters, 73
-
(1991)
Localisation of basic FGF and its mRNA after CNS injury -
L. Lillien, M. Sendtner, H. Rohrer, S. Hughes, M. Raff (1988)
Type-2 astrocyte development in rat brain cultures is initiated by a CNTF like protein produced by type-1 astrocytesNeuron, 1
-
C. Kingsley, A. Winoto (1992)
Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expressionMolecular and Cellular Biology, 12
-
Brain Res -
R. Heumann, D. Lindholm, C. Bandtlow, M. Meyer, H. Rohrer, H. Thoenen (1989)
Regulation of nerve growth factor synthesis -
Brindle Brindle, Montminy Montminy (1992)
The CREB family of transcription activatorsCurr. Opin. Genet. Dev., 2
-
G. Prince, C. Fages, Benjamin Rolland, J. Nunez, M. Tardy (1991)
DBcAMP effect on the expression of GFAP and of its encoding mRNA in astroglial primary culturesGlia, 4
-
(1991)
Stimulation of adenosine 3', 5'-monophosphate accumulation by calcitonin gene-related peptide in astrocyte cultures from neonatal rat brain -
William, Ft. Woodward, Rae, Nishi, Charles, K. Meshul, Tracey, E. Williams, Margaret, Coulombe, Felix, P. Eckenstein (1992)
Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons, 12
-
D. Fawthrop, R. Evans (1987)
Morphological changes in cultured astrocytes following exposure to calcium ionophoresNeuroscience Letters, 81
-
S. Narumi, H. Kimelberg, R. Bourke (1978)
EFFECTS OF NOREPINEPHRINE ON THE MORPHOLOGY AND SOME ENZYME ACTIVITIES OF PRIMARY MONOLAYER CULTURES FROM RAT BRAINJournal of Neurochemistry, 31
-
G. Bancroft, R. Schreiber, G. Bosma, M. Bosma, E. Unanue (1987)
A T cell-independent mechanism of macrophage activation by interferon-gamma.Journal of immunology, 139 4
-
Frohmann Frohmann (1990)
Rapid amplification of cDNA ends (RACE): User‐friendly cDNA cloningAmplifications (Perkin Elmer Cetus), 5
-
R. Hughes, M. Sendtner, M. Goldfarb, D. Lindholm, H. Thoenen (1993)
Evidence that fibroblast growth factor 5 is a major muscle-derived survival factor for cultured spinal motoneuronsNeuron, 10
-
A T cellindependant mechanism of macrophage activation by interferon, ! -
K. Bergsteindottir, A. Brennan, K. Jessen, R. Mirsky (1992)
In the presence of dexamethasone, gamma interferon induces rat oligodendrocytes to express major histocompatibility complex class II molecules.Proceedings of the National Academy of Sciences of the United States of America, 89
-
M. Sendtner, K. Stöckli, H. Thoenen (1992)
Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regenerationThe Journal of Cell Biology, 118
-
G. Wong, P. Bartlett, I. Clark‐Lewis, F. Battye, J. Schrader (1984)
Inducible expression of H–2 and Ia antigens on brain cellsNature, 310
-
F. Zafra, D. Lindholm, E. Castrén, J. Hartikka, H. Thoenen (1992)
Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes, 12
-
R (987) A T cell-independant mechanism of macrophage activation by interferon-,! -
M. Sendtner, G. Kreutzberg, H. Thoenen (1990)
Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomyNature, 345
-
D. Lindholm, E. Castrén, R. Kiefer, F. Zafra, H. Thoenen (1992)
Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferationThe Journal of Cell Biology, 117
-
U. Ernsberger, M. Sendtner, H. Rohrer (1989)
Proliferation and differentiation of embryonic chick sympathetic neurons: Effects of ciliary neurotrophic factorNeuron, 2
-
M. Meyer, I. Matsuoka, Cynthia Wetmore, L. Olson, H. Thoenen (1992)
Enhanced synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNAThe Journal of Cell Biology, 119
-
(1981)
Forskolin: A unique -
M. Hatten, M. Lynch, R. Rydel, J. Sanchez, J. Joseph‐Silverstein, D. Moscatelli, D. Rifkin (1988)
In vitro neurite extension by granule neurons is dependent upon astroglial-derived fibroblast growth factor.Developmental biology, 125 2
-
H. Schooltink, T. Stoyan, E. Roeb, P. Heinrich, S. Rose-John (1992)
Ciliary neurotrophic factor induces acute‐phase protein expression in hepatocytesFEBS Letters, 314
-
N. Ip, S. Wiegand, J. Morse, J. Rudge (1993)
Injury‐induced Regulation of Ciliary Neurotrophic Factor mRNA in the Adult Rat BrainEuropean Journal of Neuroscience, 5
-
M. Spranger, D. Lindholm, C. Bandtlow, R. Heumann, H. Gnahn, M. Näher-Noé, H. Thoenen (1990)
Regulation of Nerve Growth Factor (NGF) Synthesis in the Rat Central Nervous System: Comparison between the Effects of Interleukin‐1 and Various Growth Factors in Astrocyte Cultures and in vivoEuropean Journal of Neuroscience, 2
-
D. Baird (1990)
Regulation of cAMP-inducible genes by CREB -
A (1986) Splicing of RNA precursors -
(1991)
DBcAMP effect on the expression ofGF -
L.-F. Lin, D. Mismer, J. Lile, L. Armes, E. Butler, J. Vannice, F. Collins (1989)
Purification, cloning, and expression of ciliary neurotrophic factor (CNTF).Science, 246 4933
-
G. Hagen, S. Müller, M. Beato, G. Suske (1992)
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes.Nucleic acids research, 20 21
-
F. Perraud, G. Labourdette, F. Eclancher, M. Sensenbrenner (1990)
Primary cultures of astrocytes from different brain areas of newborn rats and effects of basic fibroblast growth factor.Developmental neuroscience, 12 1
-
(1991)
Cell-type-specific regulation of nerve growth factor (NGF) synthesis in non-neuronal cells: Comparison of Schwann cells with other cell -
A (990) Acidic and basic fibroblast growth factors show individual time-related responses following central nervous system lesion -
J. Louis, E. Magal, S. Takayama, S. Varon (1993)
CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced deathScience, 259
-
R. Oppenheim, D. Prevette, Q. Yin, F. Collins, J. MacDonald (1991)
Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor.Science, 251 5001
-
Kempski Kempski, Wroblewska Wroblewska, Spatz Spatz (1987)
Effect of forskolin on morphology of cultured glia and cerebrovascular endothelial and smooth muscle cellsInt. J. Dev. Neurosci., 5
-
S. Smale, D. Baltimore (1989)
The “initiator” as a transcription control elementCell, 57
-
G. Barbin, M. Manthorpe, S. Varon (1984)
Purification of the Chick Eye Ciliary Neuronotrophic FactorJournal of Neurochemistry, 43
-
Woodward Woodward, Nishi Nishi, Meshul Meshul, Williams Williams, Coulombe Coulombe, Eckenstein Eckenstein (1992)
Nuclear and cytoplasmic localization of basic growth factor in astrocytes and CA2 hippocampal neuronsJ. Neurosci., 12
-
R. Myers, K. Tilly, T. Maniatis (1986)
Fine structure genetic analysis of a beta-globin promoter.Science, 232 4750
-
A. Symes, M. Rao, S. Lewis, S. Landis, S. Hyman, J. Fink (1993)
Ciliary neurotrophic factor coordinately activates transcription of neuropeptide genes in a neuroblastoma cell line.Proceedings of the National Academy of Sciences of the United States of America, 90
-
C. Edmonds, C. Willis (1990)
Aldosterone and thyroid hormone interaction on the sodium and potassium transport pathways of rat colonic epithelium.The Journal of endocrinology, 124 1
-
L. Erkman, L. Wuarin, D. Cadelli, A. Kato (1989)
Interferon induces astrocyte maturation causing an increase in cholinergic properties of cultured human spinal cord cells.Developmental biology, 132 2
-
Paul Brindle, M. Montminy (1992)
The CREB family of transcription activatorsCurrent Biology, 2
-
D. Calker, M. Müller, B. Hamprecht (1980)
Regulation by secretin, vasoactive intestinal peptide, and somatostatin of cyclic AMP accumulation in cultured brain cells.Proceedings of the National Academy of Sciences of the United States of America, 77 11
-
D. Lindholm, R. Heumann, B. Hengerer, H. Thoenen (1988)
Interleukin 1 increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts.The Journal of biological chemistry, 263 31
- Publisher
- Wiley
- Copyright
- Copyright © 1993 Wiley‐Liss, Inc.
- ISSN
- 0894-1491
- eISSN
- 1098-1136
- DOI
- 10.1002/glia.440090303
- pmid
- 8294148
- Publisher site
- See Article on Publisher Site
Abstract
The structure of the rat ciliary neurotrophic factor (CNTF) gene and the regulation of CNTF mRNA levels in cultured glial cells were investigated. The rat mRNA is encoded by a simple two‐exon transcription unit. Sequence analysis of the region upstream of the transcription start‐site did not reveal a typical TATA‐box consensus sequence. Low levels of CNTF mRNA were detected in cultured Schwann cells, and CNTF mRNA was not increased by a variety of treatments. Three‐week‐old astrocyte‐enriched cell cultures from new‐born rat brain contained easily detectable CNTF mRNA. In astrocyte‐enriched cultures, upregulation of CNTF mRNA levels was observed after treatment with IFN‐γ. CNTF mRNA levels were down‐regulated in these cells by treatments that elevate intracellular cyclic AMP and by members of the fibroblast growth factor (FGF) family. The implications of these results for potential in vivo functions of CNTF are discussed. © 1993 Wiley‐Liss, Inc.
Journal
Glia – Wiley
Published: Nov 1, 1993