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References (45)
-
S. Wesselborg, I. Engels, E. Rossmann, M. Los, K. Schulze-Osthoff (1999)
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction.Blood, 93 9
-
Shinichirou Okuno, S. Shimizu, Toshinori Ito, M. Nomura, E. Hamada, Y. Tsujimoto, H. Matsuda (1998)
Bcl-2 Prevents Caspase-independent Cell Death*The Journal of Biological Chemistry, 273
-
M. Müschen, U. Warskulat, B. Schmidt, W. Schulz, D. Häussinger (1998)
Regulation of CD95 (Apo-1/Fas) Ligand and Receptor Expression in Human Embryonal Carcinoma Cells by Interferon γ and all-trans Retinoic Acid, 379
-
S. Fulda, M. Los, C. Friesen, K. Debatin (1998)
Chemosensitivity of solid tumor cells in vitro is related to activation of the CD95 systemInternational Journal of Cancer, 76
-
D. Ferrari, Anna Stępczyńska, M. Los, S. Wesselborg, K. Schulze-Osthoff (1998)
Differential Regulation and ATP Requirement for Caspase-8 and Caspase-3 Activation during CD95- and Anticancer Drug–induced ApoptosisThe Journal of Experimental Medicine, 188
-
P. Beresford, Z. Xia, A. Greenberg, J. Lieberman (1999)
Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation.Immunity, 10 5
-
Hiroshi Arai, David Gordon, E. Nabel, G. Nabel (1997)
Gene transfer of Fas ligand induces tumor regression in vivo.Proceedings of the National Academy of Sciences of the United States of America, 94 25
-
T. Sayers, A. Brooks, J. Lee, R. Fenton, K. Komschlies, J. Wigginton, R. Winkler-Pickett, R. Wiltrout (1998)
Molecular mechanisms of immune-mediated lysis of murine renal cancer: differential contributions of perforin-dependent versus Fas-mediated pathways in lysis by NK and T cells.Journal of immunology, 161 8
-
T. Hirsch, P. Marchetti, S. Susin, B. Dallaporta, N. Zamzami, I. Marzo, M. Geuskens, G. Kroemer (1997)
The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell deathOncogene, 15
-
A. Piché, J. Grim, C. Rancourt, J. Gómez-Navarro, John Reed, D. Curiel (1998)
Modulation of Bcl-2 protein levels by an intracellular anti-Bcl-2 single-chain antibody increases drug-induced cytotoxicity in the breast cancer cell line MCF-7.Cancer research, 58 10
-
Nancy Thornberry, Y. Lazebnik (1998)
Caspases: enemies within.Science, 281 5381
-
M. Weller, M. Schuster, T. Pietsch, M. Schabet (1998)
CD95 ligand-induced apoptosis of human medulloblastoma cells.Cancer letters, 128 2
-
D. McConkey, J. Chandra, S. Wright, W. Plunkett, T. McDonnell, John Reed, M. Keating (1996)
Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of BCL-2 and BAX.Journal of immunology, 156 7
-
S Fulda, M Los, C Friesen, KM. Debatin (1998)
Chemosensitivity of Apoptosis V. M. Kolenko et al. solid tumor cells in vitro is related to activation of the CD95 systemInt J Cancer, 76
-
(2000)
Chemosensitivity of Apoptosis -
Yusuf Hannun (1997)
Apoptosis and the dilemma of cancer chemotherapy.Blood, 89 6
-
V. Kolenko, R. Uzzo, R. Bukowski, N. Bander, A. Novick, E. Hsi, J. Finke (1999)
Dead or dying: necrosis versus apoptosis in caspase-deficient human renal cell carcinoma.Cancer research, 59 12
-
W. Roth, B. Wagenknecht, J. Dichgans, M. Weller (1998)
Interferon-α enhances CD95L-induced apoptosis of human malignant glioma cellsJournal of Neuroimmunology, 87
-
M. Tolomeo, L. Dusonchet, M. Meli, S. Grimaudo, N. D’alessandro, G. Papoff, G. Ruberti, L. Rausa (1998)
The CD95/CD95 ligand system is not the major effector in anticancer drug-mediated apoptosisCell Death and Differentiation, 5
-
H. Hirata, A. Takahashi, Susumu Kobayashi, S. Yonehara, H. Sawai, T. Okazaki, Kokichi Yamamoto, M. Sasada (1998)
Caspases Are Activated in a Branched Protease Cascade and Control Distinct Downstream Processes in Fas-induced ApoptosisThe Journal of Experimental Medicine, 187
-
J. Xiang, D. Chao, S. Korsmeyer (1996)
BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases.Proceedings of the National Academy of Sciences of the United States of America, 93 25
-
C. Friesen, S. Fulda, K. Debatin (1997)
Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cellsLeukemia, 11
-
R Johnstone, E. Cretney, Mark Smyth (1999)
P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death.Blood, 93 3
-
C. Scaffidi, S. Fulda, A. Srinivasan, C. Friesen, Feng Li, K. Tomaselli, K. Debatin, P. Krammer, M. Peter (1998)
Two CD95 (APO‐1/Fas) signaling pathwaysThe EMBO Journal, 17
-
M. Koshiji, Y. Adachi, S. Sogo, S. Taketani, N. Oyaizu, S. Than, M. Inaba, S. Phawa, K. Hioki, S. Ikehara (1998)
Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-alpha (TNF-alpha) and/or interferon-gamma (IFN-gamma), resulting from down-modulation of Bcl-2 expression.Clinical and experimental immunology, 111 1
-
M. Clément, J. Hirpara, Sanaul-Haq Chawdhury, S. Pervaiz (1998)
Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells.Blood, 92 3
-
N. Rampino, H. Yamamoto, Y. Ionov, Y. Li, H. Sawai, John Reed, M. Perucho (1997)
Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator PhenotypeScience, 275
-
John Reed (1999)
Mechanisms of apoptosis avoidance in cancer.Current opinion in oncology, 11 1
-
S. Chi, C. Kitanaka, K. Noguchi, T. Mochizuki, Y. Nagashima, M. Shirouzu, H. Fujita, Midori Yoshida, Wenbin Chen, A. Asai, M. Himeno, S. Yokoyama, Y. Kuchino (1999)
Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cellsOncogene, 18
-
Maccon Keane, S. Ettenberg, Geoffrey Lowrey, Edward Russell, S. Lipkowitz (1996)
Fas expression and function in normal and malignant breast cell lines.Cancer research, 56 20
-
M. Pinkoski, M. Hobman, J. Heibein, K. Tomaselli, Feng Li, P. Seth, C. Froelich, R. Bleackley (1998)
Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.Blood, 92 3
-
A. Sarin, Mark S. Williams, M. Alexander-Miller, J. Berzofsky, C. Zacharchuk, P. Henkart (1997)
Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases.Immunity, 6 2
-
M. Martínez-Lorenzo, S. Gamen, Jaime Etxeberria, P. Lasierra, L. Larrad, A. Piñeiro, A. Anel, J. Naval, M. Alava (1998)
Resistance to apoptosis correlates with a highly proliferative phenotype and loss of Fas and CPP32 (caspase‐3) expression in human leukemia cellsInternational Journal of Cancer, 75
-
Koshiji, Adachi, Sogo, Taketani, Oyaizu, Than, Inaba, Phawa, Hioki, Ikehara (1998)
Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor‐alpha (TNF‐α) and/or interferon‐gamma (IFN‐γ), resulting from down‐modulation of Bcl‐2 expressionClinical & Experimental Immunology, 111
-
D Ferrari, A Stepczynska, M Los, S Wesselborg, K. Schulze-Osthoff (1998)
Differential regulation and ATP requirement for caspase-8 and caspase-3 activation duringJ Exp Med., 188
-
A. Bloem, H. Lockhorst (1999)
Bcl-2 antisense therapy in multiple myeloma.Pathologie-biologie, 47 2
-
T. Hedlund, S. Meech, Sampathkumar Srikanth, A. Kraft, G. Miller, J. Schaack, R. Duke (1999)
Adenovirus-mediated expression of Fas ligand induces apoptosis of human prostate cancer cellsCell Death and Differentiation, 6
-
Isabella Reiter, Barbara Krammer, G. Schwamberger (1999)
Cutting edge: differential effect of apoptotic versus necrotic tumor cells on macrophage antitumor activities.Journal of immunology, 163 4
-
O. Micheau, E. Solary, A. Hammann, M. Dimanche-Boitrel (1999)
Fas Ligand-independent, FADD-mediated Activation of the Fas Death Pathway by Anticancer Drugs*The Journal of Biological Chemistry, 274
-
Y. Tu, S. Renner, F. Xu, A. Fleishman, J. Taylor, J. Weisz, R. Vescio, M. Rettig, J. Berenson, S. Krajewski, John Reed, A. Lichtenstein (1998)
BCL-X expression in multiple myeloma: possible indicator of chemoresistance.Cancer research, 58 2
-
Martina Müller, S. Strand, H. Hug, Eva Heinemann, H. Walczak, W. Hofmann, W. Stremmel, P. Krammer, P. Galle (1997)
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.The Journal of clinical investigation, 99 3
-
W. Roth, B. Wagenknecht, J. Dichgans, M. Weller (1998)
Interferon-alpha enhances CD95L-induced apoptosis of human malignant glioma cells.Journal of neuroimmunology, 87 1-2
-
H. Bantel, I. Engels, W. Voelter, K. Schulze-Osthoff, S. Wesselborg (1999)
Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis.Cancer research, 59 9
-
M. Los, I. Herr, C. Friesen, S. Fulda, K. Schulze-Osthoff, K. Debatin (1997)
Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases).Blood, 90 8
-
M. Smyth, Erika Krasovskis, V. Sutton, R. Johnstone (1998)
The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis.Proceedings of the National Academy of Sciences of the United States of America, 95 12
- Publisher
- Springer Journals
- Copyright
- Copyright © 2000 by Kluwer Academic Publishers
- Subject
- Medicine & Public Health; Cancer Research; Virology; Anatomy; Oncology; Biochemistry, general
- ISSN
- 1360-8185
- eISSN
- 1573-675X
- DOI
- 10.1023/A:1009677307458
- Publisher site
- See Article on Publisher Site
Abstract
The majority of current anticancer therapies induce tumor cell death through the induction of apoptosis. Alterations in the apoptotic pathways may determine tumor resistance to these therapies. Activation of the proteolytic cascade involving caspase family members is a critical component of the execution of cell death in apoptotic cells. However, recent studies suggest that cell death can proceed in the absence of caspases. In this review we describe the role of caspase-dependent and -independent pathways as targets for anticancer treatment; better understanding of diverse modes of tumor cell death will help to avoid ineffective treatment and provide a molecular basis for the new strategies targeting caspase-independent death pathways in apoptosis-resistant forms of cancer.
Journal
Apoptosis – Springer Journals
Published: Oct 1, 2004