Access the full text.
Sign up today, get DeepDyve free for 14 days.
M. Kainer, J. Linden, D. Whaley, H. Holmes, W. Jarvis, D. Jernigan, L. Archibald (2004)
Clostridium infections associated with musculoskeletal-tissue allografts.The New England journal of medicine, 350 25
Y. Zhang, D. Homsi, K. Gates, K. Oakes, V. Sutherland, L. Wolfinbarger (1994)
A comprehensive study of physical parameters, biomechanical properties, and statistical correlations of iliac crest bone wedges used in spinal fusion surgery. IV. Effect of gamma irradiation on mechanical and material properties.Spine, 19 3
Gibbon Mj, D. Butler, E. Grood, D. Bylski-Austrow, M. Levy, F. Noyes (1991)
Effects of gamma irradiation on the initial mechanical and material properties of goat bone‐patellar tendon‐bone allograftsJournal of Orthopaedic Research, 9
S. Stramer, S. Glynn, S. Kleinman, D. Strong, S. Caglioti, D. Wright, R. Dodd, M. Busch (2004)
Detection of HIV-1 and HCV infections among antibody-negative blood donors by nucleic acid-amplification testing.The New England journal of medicine, 351 8
E. Kempner, H. Haigler (1982)
The influence of low temperature on the radiation sensitivity of enzymes.The Journal of biological chemistry, 257 22
M. Anderson, J. Keyak, H. Skinner (1992)
Compressive mechanical properties of human cancellous bone after gamma irradiation.The Journal of bone and joint surgery. American volume, 74 5
A. Hamer, J. Strachan, M. Black, C. Ibbotson, Ian Stockley, R. Elson (1996)
Biochemical properties of cortical allograft bone using a new method of bone strength measurement. A comparison of fresh, fresh-frozen and irradiated bone.The Journal of bone and joint surgery. British volume, 78 3
L. Wolfinbarger, Y. Zhang, B. Adam, V. Sutherland, K. Gates, B. Brame (1994)
A comprehensive study of physical parameters, biomechanical properties, and statistical correlations of iliac crest bone wedges used in spinal fusion surgery. II. Mechanical properties and correlation with physical parameters.Spine, 19 3
MJ Anderson, JH Keyak, HB Skinner (1992)
Compressive mechanical properties of human Cloward bone after gamma irradiationJ Bone Joint Surg Am, 74
David Jones, P. Huddleston, M. Zobitz, M. Stuart (2007)
Mechanical properties of patellar tendon allografts subjected to chemical sterilization.Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 23 4
R. Peterson, W. Shelton, Anna Bomboy (2001)
Allograft versus autograft patellar tendon anterior cruciate ligament reconstruction: A 5-year follow-up.Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 17 1
(2004)
Adaptation of ANSI/AAMI/ISO 11137 Method 2B sterilization validation for medical devices to tissue banking
O. Cornu, X. Banse, P. Docquier, S. Luyckx, C. Delloye (2000)
Effect of freeze‐drying and gamma irradiation on the mechanical properties of human cancellous boneJournal of Orthopaedic Research, 18
A. Salehpour, D. Butler, F. Proch, H. Schwartz, S. Feder, C. Doxey, A. Ratcliffe (1995)
Dose‐dependent response of gamma irradiation on mechanical properties and related biochemical composition of goat bone‐patellar tendon‐bone allograftsJournal of Orthopaedic Research, 13
L. Wolfinbarger, Y. Zhang, B. Adam, V. Sutherland, D. Homsi, B. Brame (1994)
A comprehensive study of physical parameters, biomechanical properties, and statistical correlations of iliac crest bone wedges used in spinal fusion surgery. I. Physical parameters and their correlations.Spine, 19 3
(2002)
Update: allograft-associated bacterial infections – United States, 2002MMWR Morb Mortal Wkly Rep, 51
C. Vangsness, Phillip Wagner, T. Moore, Michael Roberts (2006)
Overview of safety issues concerning the preparation and processing of soft-tissue allografts.Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 22 12
C. Vangsness, Ivan Garcia, C. Mills, M. Kainer, Michael Roberts, T. Moore (2003)
Allograft Transplantation in the Knee: Tissue Regulation, Procurement, Processing, and SterilizationThe American Journal of Sports Medicine, 31
YX Zhang, D Homsi, K Gates, K Oakes, V Sutherland, L Wolfinbarger (1994)
A comprehensive study of physical parameters, biomechanical properties and statistical correlations of iliac crest wedges used in spinal fusion surgery. IV: effect of gamma irradiation on mechanical strengthSpine, 19
Teri Grieb, R. Forng, R. Stafford, Jack Lin, J. Almeida, S. Bogdansky, Chad Ronholdt, W. Drohan, W. Burgess (2005)
Effective use of optimized, high-dose (50 kGy) gamma irradiation for pathogen inactivation of human bone allografts.Biomaterials, 26 14
S. Gasser, R. Uppal (2006)
Anterior cruciate ligament reconstruction: a new technique for Achilles tendon allograft preparation.Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 22 12
C. Smith, I. Young, J. Kearney (1996)
Mechanical properties of tendons: changes with sterilization and preservation.Journal of biomechanical engineering, 118 1
D. Mcallister, M. Joyce, Barton Mann, Chris Thomas, Vangsness (2010)
The Current Status of Tissue Regulation, Procurement, Processing, and Sterilization
(2002)
Update: allograft-associated bacterial infections--United States, 2002.MMWR. Morbidity and mortality weekly report, 51 10
A. Hamer, J. Strachan, M. Black, C. Ibbotson, I. Stockley, R. Elson (1996)
BIOMECHANICAL PROPERTIES OF CORTICAL ALLOGRAFT BONE USING A NEW METHOD OF BONE STRENGTH MEASUREMENTJournal of Bone and Joint Surgery-british Volume, 78
B. Fideler, C. Vangsness, Bin Lu, C. Orlando, T. Moore (1995)
Gamma Irradiation: Effects on Biomechanical Properties of Human Bone-Patellar Tendon-Bone AllograftsThe American Journal of Sports Medicine, 23
A. Hamer, I. Stockley, R. Elson (1999)
Changes in allograft bone irradiated at different temperatures.The Journal of bone and joint surgery. British volume, 81 2
S. Biramontri, N. Haneda, H. Tachibana, T. Kojima (1996)
Effect of low irradiation temperature on the gamma-ray response of dyed and undyed PMMA dosimetersRadiation Physics and Chemistry, 48
(2004)
AATB Bulletin No. 04-42 - Implementation of nucleic acid testing (NAT)
R. Haut, Amy Powlison (1990)
The effects of test environment and cyclic stretching on the failure properties of human patellar tendonsJournal of Orthopaedic Research, 8
DR McAllister, JJ Joyce, BJ Mann, CT Vangsness (2007)
Allograft Update: the current status of tissue regulation, procurement, processing, and sterilizationAm J Sports Med, 35
Jeffrey Rihn, J. Irrgang, A. Chhabra, Freddie Fu, C. Harner (2006)
Does irradiation affect the clinical outcome of patellar tendon allograft ACL reconstruction?Knee Surgery, Sports Traumatology, Arthroscopy, 14
T. Mae, K. Shino, A. Maeda, Y. Toritsuka, S. Horibe, T. Ochi (2003)
Effect of Gamma Irradiation on Remodeling Process of Tendon AllograftClinical Orthopaedics and Related Research, 1
Huynh Nguyen, D. Morgan, M. Forwood (2006)
Sterilization of allograft bone: effects of gamma irradiation on allograft biology and biomechanicsCell and Tissue Banking, 8
J. Currey, J. Foreman, Ira Laketić, J. Mitchell, D. Pegg, G. Reilly (1997)
Effects of ionizing radiation on the mechanical properties of human boneJournal of Orthopaedic Research, 15
Teri Grieb, R. Forng, S. Bogdansky, Chad Ronholdt, B. Parks, W. Drohan, Wilson Burgess, Jack Lin (2006)
High‐dose gamma irradiation for soft tissue allografts: High margin of safety with biomechanical integrityJournal of Orthopaedic Research, 24
P. Simonian, E. Conrad, J. Chapman, R. Harrington, H. Chansky (1994)
Effect of sterilization and storage treatments on screw pullout strength in human allograft bone.Clinical orthopaedics and related research, 302
W. Ginoza (1963)
Radiosensitive Molecular Weight of Single-Stranded Virus Nucleic AcidsNature, 199
M. Eagle, P. Rooney, R. Lomas, J. Kearney (2005)
Validation of Radiation Dose Received by Frozen Unprocessed and Processed Bone during Terminal SterilisationCell and Tissue Banking, 6
Thomas Baker, Chad Ronholdt, S. Bogdansky (2005)
Validating a Low Dose Gamma Irradiation Process for Sterilizing Allografts Using ISO 11137 Method 2BCell and Tissue Banking, 6
The increased use of allograft tissue for musculoskeletal repair has brought more focus to the safety of allogenic tissue and the efficacy of various sterilization techniques. Gamma irradiation is an effective method for providing terminal sterilization to biological tissue, but it is also reported to have deleterious effects on tissue mechanics in a dose-dependent manner. At irradiation ranges up to 25 kGy, a clear relationship between mechanical strength and dose has yet to be established. The aim of this study was to investigate the mechanical properties of bone and soft tissue allografts, irradiated on dry ice at a low absorbed dose (18.3–21.8 kGy) and a moderate absorbed dose (24.0–28.5 kGy), using conventional compressive and tensile testing, respectively. Bone grafts consisted of Cloward dowels and iliac crest wedges, while soft tissue grafts consisted of patellar tendons, anterior tibialis tendons, semitendinosus tendons, and fascia lata. There were no statistical differences in mechanical strength or modulus of elasticity for any graft irradiated at a low absorbed dose, compared to control groups. Also, bone allografts and two soft tissue allografts (anterior tibialis and semitendinosus tendon) that were irradiated at a moderate dose demonstrated similar strength and modulus of elasticity values to control groups. The results of this study support the use of low dose and moderate dose gamma irradiation of bone grafts. For soft tissue grafts, the results support the use of low dose irradiation.
Cell and Tissue Banking – Springer Journals
Published: Apr 23, 2008
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.