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I. Hanbauer, J. Gimble, W. Lovenberg (1979)
Changes in soluble calmodulin following activation of dopamine receptors in rat striatal slicesNeuropharmacology, 18
R. Sweet, John Lee, H. Spiegel, F. Mcdowell (1972)
Enhanced response to low doses of levodopa after withdrawal from chronic treatmentNeurology, 22
(1983)
Covalent binding of a dopamine agonist, apomorphine, in striatum after chronic administration
Ross Baldessarini, Daniel Tarsy (1979)
Relationship of the actions of neuroleptic drugs to the pathophysiology of tardive dyskinesia.International review of neurobiology, 21
D. Chicot, R. Wright, B. Brotman, A. Prince (1975)
HEPANOSTICON IN SCREENING FOR HBsAgThe Lancet, 305
R. Bailey, D. Jackson, P. Bracs (2004)
Long-term l-Dopa pretreatment of mice: Central receptor subsensitivity or supersensitivity?Psychopharmacology, 66
(1982)
The biochemical basic of neuropharmacology
K. Moore, J. Thornburg (1975)
Drug-induced dopaminergic supersensitivity.Advances in neurology, 9
P. Nausieda, W. Weiner, D. Kanapa, H. Klawans (1978)
Bromocriptine‐induced behavioral hypersensitivityNeurology, 28
H. Klawans (1973)
The pharmacology of tardive dyskinesias.The American journal of psychiatry, 130 1
T. Ljungberg, U. Ungerstedt (1977)
Different behavioural patterns induced by apomorphine: evidence that the method of administration determines the behavioural response to the drug.European journal of pharmacology, 46 1
M. Memo, W. Lovenberg, I. Hanbauer (1982)
Agonist-induced subsensitivity of adenylate cyclase coupled with a dopamine receptor in slices from rat corpus striatum.Proceedings of the National Academy of Sciences of the United States of America, 79 14
T. Ljungberg, U. Ungerstedt (1977)
Apomorphine-induced locomotion and gnawing: evidence that the experimental design greatly influences gnawing while locomotion remains unchanged.European journal of pharmacology, 46 2
L. Nelson, G. Ellison (1978)
Enhanced stereotypies after repeated injections but not continuous amphetaminesNeuropharmacology, 17
R. Wilcox, W. Riffee, Pih-Chun Chen, S. Hammett, Robert Smith (1980)
Behavioral facilitation following chronic administration of N-n-propylnorapomorphinePsychopharmacology, 72
Marcela Bitran, Gonzalo Bustos (1982)
On the mechanism of presynaptic autoreceptor-mediated inhibition of transmitter synthesis in dopaminergic nerve terminals.Biochemical pharmacology, 31 18
B. Sahakian, T. Robbins, S. Iversen (1976)
Alpha-flupenthixol-induced hyperactivity by chronic dosing in rats.European journal of pharmacology, 37 1
O. Magnusson, L. Nilsson, D. Westerlund (1980)
Simultaneous determination of dopamine, DOPAC and homovanillic acid. Direct injection of supernatants from brain tissue homogenates in a liquid chromatography--electrochemical detection system.Journal of chromatography, 221 2
(1980)
Neurotransmitter receptors in the parkinsonian brain. In: Rinne UK, Klinger M, Stature G (eds) Parkinson's disease-current progress problems and management
M. Mello, Ana Ventura, R. Carvalho, William Klein, F. Mello (1982)
Regulation of dopamine- and adenosine-dependent adenylate cyclase systems of chicken embryo retina cells in culture.Proceedings of the National Academy of Sciences of the United States of America, 79 18
R. Post, H. Rose (1976)
Increasing effects of repetitive cocaine administration in the ratNature, 260
W. Greef, P. Plotsky, J. Neill (1981)
Dopamine levels in hypophysial stalk plasma and prolactin levels in peripheral plasma of the lactating rat: effects of a simulated suckling stimulus.Neuroendocrinology, 32 4
C. Goetz, C. Tanner, P. Nausieda (1981)
Weekly drug holiday in Parkinson diseaseNeurology, 31
W. Weiner, W. Koller, S. Perlik, P. Nausieda, H. Klawans (1980)
Drug holiday and management of Parkinson diseaseNeurology, 30
W. Weiner, C. Goetz, P. Nausieda, H. Klawans (1979)
Amphetamine‐induced hypersensitivity in guinea pigsNeurology, 29
R. Bailey, D. Jackson (1978)
A pharmacological study of changes in central nervous system receptor responsiveness after long-term dexamphetamine and apomorphine administrationPsychopharmacology, 56
C. Marsden, J. Parkes (1977)
SUCCESS AND PROBLEMS OF LONG-TERM LEVODOPA THERAPY IN PARKINSON'S DISEASEThe Lancet, 309
H. Ludin, F. Bass-Verrey (2005)
Study of deterioration in long-term treatment of parkinsonism with L-Dopa plus decarboxylase inhibitorJournal of Neural Transmission, 38
D. Burt, D. Burt, I. Creese, SolomonH Snyder (1977)
Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain.Science, 196 4287
T. Robinson, J. Becker, S. Presty (1982)
Long-term facilitation of amphetamine-induced rotational behavior and striatal dopamine release produced by a single exposure to amphetamine: Sex differencesBrain Research, 253
D. Segal, S. Weinberger, Jerome Cahill, STANLEY MCCUNNEY (1980)
Multiple Daily Amphetamine Administration: Behavioral and Neurochemical AlterationsScience, 207
R. Smith, R. Wilcox, W. Soine, W. Riffee, R. Baldessarini, N. Kula (1979)
Plasma levels of apomorphine following intravenous, intraperitoneal and oral administration to mice and rats.Research communications in chemical pathology and pharmacology, 24 3
O. Jenkins, R. Bailey, E. Crisp, D. Jackson (2004)
Subacute l-DOPA in mice: Biochemical and behavioural effectsPsychopharmacology, 68
R. Kurlan, I. Shoulson (1982)
Up and down regulation: clinical significance of nervous system receptor-drug interactions.Clinical neuropharmacology, 5 4
U. Rinne, P. Lönnberg, V. Koskinen (2005)
Dopamine receptors in the parkinsonian brainJournal of Neural Transmission, 51
J. Costentin, P. Protais, J. Schwartz (1975)
Rapid and dissociated changes in sensitivities of different dopamine receptors in mouse brainNature, 257
F. White, R. Wang (1983)
Differential effects of classical and atypical antipsychotic drugs on A9 and A10 dopamine neurons.Science, 221 4615
M. Trulson, T. Crisp (1982)
Behavioral and neurochemical effects of apomorphine in the cat.European journal of pharmacology, 80 4
P. Seeman (1980)
Brain dopamine receptors.Pharmacological reviews, 32 3
B. Costall, D. Fortune, R. Naylor, V. Nohria (1979)
A study of drug action on normal and denervated striatal mechanisms.European journal of pharmacology, 56 3
F. Hefti, E. Melamed, R. Wurtman (1980)
Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterizationBrain Research, 195
M. Memo, S. Pradhan, I. Hanbauer (1981)
Cocaine-induced supersensitivity of striatal dopamine receptors: role of endogenous calmodulinNeuropharmacology, 20
R. Post, Kopanda Rt, Black Ke (1976)
Progressive effects of cocaine on behavior and central amine metabolism in rhesus monkeys: relationship to kindling and psychosis.Biological psychiatry, 11 4
T. Ljungberg, U. Ungerstedt (1978)
Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: Evidence for two different mechanisms of actionPsychopharmacology, 56
U. Ungerstedt (1971)
Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system.Acta physiologica Scandinavica. Supplementum, 367
O. Magnusson, B. NilssonL, D. Westerlund (1980)
ドーパミン,DOPAC(3,4-ジヒドロキシフェニル酢酸)およびホモバニリン酸の同時定量 脳組織ホモジネート上澄液の液体クロマトグラフィー-電気化学検出系への直接導入Journal of Chromatography A, 221
N. Montanaro, R. Dall'olio, O. Gandolfi, A. Vaccheri (1982)
Differential enhancement of behavioral sensitivity to apomorphine following chronic treatment of rats with (-)-sulpiride and haloperidol.European journal of pharmacology, 81 1
T. Seeger, L. Thal, E. Gardner (2004)
Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: Studies with chronic clozapine and haloperidolPsychopharmacology, 76
P. Muller, P. Seeman (1978)
Dopaminergic supersensitivity after neuroleptics: Time-course and specificityPsychopharmacology, 60
M. Nowycky, R. Roth (1978)
Dopaminergic neurons: Role of presynaptic receptors in the regulation of transmitter biosynthesisProgress in Neuro-psychopharmacology, 2
Hirokazu Watanabe, S. Nakano, N. Ogawa (2004)
Age difference in apomorphine-induced stereotypy in rats: Relationship to plasma and brain concentrationsPsychopharmacology, 76
A. Carlsson, M. Lindqvist (2009)
EFFECT OF CHLORPROMAZINE OR HALOPERIDOL ON FORMATION OF 3METHOXYTYRAMINE AND NORMETANEPHRINE IN MOUSE BRAIN.Acta pharmacologica et toxicologica, 20
L. Direnfeld, R. Feldman, M. Alexander, M. Kelly‐Hayes (1980)
Is L‐DOPA drug holiday useful?Neurology, 30
W. Koller (1982)
Alternate day levodopa therapy in parkinsonismNeurology, 32
P. Vonvoigtlander, E. Losey, H. Triezenberg (1975)
Increased sensitivity to dopaminergic agents after chronic neuroleptic treatment.The Journal of pharmacology and experimental therapeutics, 193 1
213 85 85 3 3 R. Castro P. Abreu C. H. Calzadilla M. Rodriguez Department of Physiology and Biochemistry, School of Medicine University of La Laguna Canary Islands Spain Abstract Administration of drugs that reduce the influence of dopamine at its receptor site can lead to postsynaptic supersensitivity, whereas treatment with dopamine (DA) agonists can cause postsynaptic subsensitivity. Both unaltered and enhanced postsynaptic responses to DA have been shown after pretreatment with DA agonists. In the present manuscript pretreatment with apomorphine, a dopaminergic agonist, is shown to induce either increased or reduced locomotor activity. When a drug-free period between successive injections was allowed, apomorphine induced an enhanced locomotor response, whereas a reduced response occurred when each dose was injected before the previous apomorphine dose had been completely metabolized. Pretreatment with both high (1 and 3 mg/kg) and low (0.05 mg/kg) apomorphine doses enhanced the response. Apomorphine treatment that caused enhanced locomotor responses did not modify the stereotypy response to the drug. Similar enhanced or reduced response were found in rats with partial lesions of the nigrostriatal system. These altered responses to DA agonists may have important clinical consequences. The present data also suggest the existence of a different DA systems for locomotor and stereotypy actions of dopaminergic agonists.
Psychopharmacology – Springer Journals
Published: Mar 1, 1985
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