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C. Huber, E. Dworzak, U. Fink, G. Michlmayr, H. Braunsteiner, H. Huber (1974)
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High‐frequency establishment of human immunoglobulin‐producing lymphoblastoid lines from normal and malignant lymphoid tissue and peripheral bloodInternational Journal of Cancer, 8
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SURFACE MARKERS ON HUMAN T AND B LYMPHOCYTESThe Journal of Experimental Medicine, 136
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Zur funktionellen Differenzierung lymphatischer Zellen: Lymphocyten mit Immunglobulindeterminanten und Bindungsfähigkeit für Immunkomplexe bei der MausZeitschrift für die gesamte experimentelle Medizin einschließlich experimentelle Chirurgie, 156
(1975)
is establishing Annual Awards in Cancer Immunology. To inaugurate the program immediate clinical significance. Nominations, which should be addressed t o Murrs. Helen C. Nauts, Executive Director
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M. Raff, M. Sternberg, R. Taylor (1970)
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Volker Brade, A. Nicholson, Gerald Lee, Manfred Mayer (1974)
The reaction of zymosan with the properdin system: isolation of purified factor D from guinea pig serum and study of its reaction characteristics.Journal of immunology, 112 5
In the present article we describe a simple rosette assay for detection of C3 receptor‐bearing B lymphocytes with complement (C)‐coated zymosan (Zy) beads. Zy coated with murine or human C bound to a distinct population of human and mouse lymphocytes as well as to the majority of lymphoblastoid cells of several human established cell lines. Rosette formation was also observed with human red blood cells, with human monocytes and neutrophils. Experiments with anti‐immunoglobulin sera, with other B and T cell markers and with mouse thymocytes proved that the capacity to bind C‐coated Zy is primarily a feature of B lymphocytes. The following findings suggested that C‐coated Zy is bound via receptor sites for the activated components of C3: (a) Zy coated with C3‐deficient serum failed to bind, (b) comparable percentages of various lymphoid and nonlymphoid cells formed rosettes with C‐coated Zy as well as with antibody and C‐coated sheep red bloodcells, and (c) antibodies against human or murine C3 inhibited the binding of C‐coated Zy.
European Journal of Immunology – Wiley
Published: Jun 1, 1975
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