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68Ga-FAPI PET/CT: Tracer Uptake in 28 Different Kinds of CancerThe Journal of Nuclear Medicine, 60
- Publisher
- Wolters Kluwer Health
- Copyright
- Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
- ISSN
- 0363-9762
- eISSN
- 1536-0229
- DOI
- 10.1097/RLU.0000000000003231
- Publisher site
- See Article on Publisher Site
Abstract
Abstract We presented a case of 64-year-old woman with pathologically diagnosed lung adenocarcinoma. Brain metastases were highly suspected due to the appearance of neurological symptoms. However, no abnormal finding in the brain was observed on 18F-FDG PET/CT. Contrast-enhanced MRI showed the presence of leptomeningeal metastases but with a negative cerebrospinal fluid analysis. For this reason, the patient underwent 68Ga-FAPI PET/CT, later fused with MRI scans that showed intense uptake of 68Ga-FAPI in leptomeningeal regions correspondent to the sites of gadolinium enhancement. This case highlights that 68Ga-FAPI would be promising for the identification of leptomeningeal involvement in patients with malignant disease.
Journal
Clinical Nuclear Medicine – Wolters Kluwer Health
Published: Apr 1, 180