Access the full text.
Sign up today, get DeepDyve free for 14 days.
J. Malison, T. Kayes, B. Wentworth, C. Amundson (1988)
Growth and Feeding Responses of Male versus Female Yellow Perch (Perca flavescens) Treated with Estradiol-17βCanadian Journal of Fisheries and Aquatic Sciences, 45
M. Ahel, T. Conrad, W. Giger (1987)
Persistent organic chemicals in sewage effluents. 3. Determinations of nonylphenoxy carboxylic acids by high-resolution gas chromatography/mass spectrometry and high-performance liquid chromatography.Environmental science & technology, 21 7
S. Jobling, M. Nolan, C. Tyler, G. Brighty, J. Sumpter (1998)
Widespread Sexual Disruption in Wild FishEnvironmental Science & Technology, 32
T. Yamamoto (1965)
Estriol-induced XY females of the medaka (Oryzias latipes) and their progenies.General and comparative endocrinology, 5 5
E. Routledge, J. Sumpter (1996)
Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screenEnvironmental Toxicology and Chemistry, 15
Y. Allen, A. Scott, P. Matthiessen, S. Haworth, J. Thain, S. Feist (1999)
Survey of estrogenic activity in United Kingdom estuarine and coastal waters and its effects on gonadal development of the flounder Platichthys flesusEnvironmental Toxicology and Chemistry, 18
Hing‐Biu Lee, Jianhua. Weng, T. Peart, R. Maguire (1998)
Occurrence of Alkylphenoxyacetic Acids in Canadian Sewage Treatment Plant EffluentsWater Quality Research Journal of Canada, 33
T. Yamamoto (1959)
The effects of estrone dosage level upon the percentage of sex-reversals in genetic male (XY) of the medaka (Oryzias latipes).The Journal of experimental zoology, 141
M. Gray, C. Metcalfe (1997)
Induction of testis‐ova in Japanese medaka (Oryzias latipes) exposed to p‐nonylphenolEnvironmental Toxicology and Chemistry, 16
E. Stephanou, W. Giger (1982)
Persistent organic chemicals in sewage effluents. 2. Quantitative determinations of nonylphenols and nonylphenol ethoxylates by glass capillary gas chromatography.Environmental science & technology, 16 11
Lee (1998)
Determination of 17β-estradiol and its metabolites in sewage effluent by solid-phase extraction and gas chromatography/mass spectrometryJ Assoc Off Anal Chem, 81
A. Nimrod, W.H Benson (1998)
Reproduction and development of Japanese medaka following an early life stage exposure to xenoestrogensAquatic Toxicology, 44
H. Lee, T. Peart (1998)
Determination of 17 beta-estradiol and its metabolites in sewage effluent by solid-phase extraction and gas chromatography/mass spectrometry.Journal of AOAC International, 81 6
Metcalfe Metcalfe, Metcalfe Metcalfe, Kiparissis Kiparissis, Niimi Niimi, Foran Foran, Benson Benson (2000)
Gonadal development and endocrine responses in Japanese medaka ( Oryzias latipes ) exposed to o,p' ‐DDT in water and through transgenerational pathwaysEnviron Toxicol Chem, 19
K. Hanaoka (1968)
[Sex differentiation].Horumon to rinsho. Clinical endocrinology, 16 1
J. Sumpter (1995)
Feminized responses in fish to environmental estrogens.Toxicology letters, 82-83
Allen (1999)
Survey of estrogenic activity in United Kingdom estuarine and coastal waters and its effects on gonadal development of the flounder Platichthys flesusEnviron Toxicol Chem., 18
W. Hartley, A. Thiyagarajah, M. Anderson, M. Broxson, S. Major, S. Zell (1998)
Gonadal development in Japanese medaka (Oryzias latipes) exposed to 17 β-estradiolMarine Environmental Research, 46
E. Routledge, D. Sheahan, C. Desbrow, G. Brighty, M. Waldock, J. Sumpter (1998)
Identification of Estrogenic Chemicals in STW Effluent. 2. In Vivo Responses in Trout and RoachEnvironmental Science & Technology, 32
T. Metcalfe, C. Metcalfe, Y. Kiparissis, A. Niimi, C. Foran, W. Benson (2000)
Gonadal development and endocrine responses in Japanese medaka (Oryzias latipes) exposed to o,p′‐DDT in water or through maternal transferEnvironmental Toxicology and Chemistry, 19
P. Hansen, H. Dizer, B. Hock, A. Marx, J. Sherry, M. Mcmaster, C. Blaise (1998)
VITELLOGENIN : A BIOMARKER FOR ENDOCRINE DISRUPTORSTrends in Analytical Chemistry, 17
D. Larsson, M. Adolfsson‐Erici, J. Parkkonen, M. Pettersson, A. Berg, P. Olsson, L. Förlin (1999)
ETHINYLOESTRADIOL - AN UNDESIRED FISH CONTRACEPTIVEAquatic Toxicology, 45
M. Gray, A. Niimi, C. Metcalfe (1999)
Factors affecting the development of testis‐ova in medaka, Oryzias latipes, exposed to octylphenolEnvironmental Toxicology and Chemistry, 18
J. Brotons, M. Olea-Serrano, M. Villalobos, V. Pedraza, N. Olea (1995)
Xenoestrogens released from lacquer coatings in food cans.Environmental Health Perspectives, 103
E. Bennett, C. Metcalfe (2000)
Distribution of degradation products of alkylphenol ethoxylates near sewage treatment plants in the lower Great Lakes, North AmericaEnvironmental Toxicology and Chemistry, 19
S. Jobling, T. Reynolds, Roger White, Malcolm Parker, J. Sumpter (1995)
A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic.Environmental Health Perspectives, 103
C. Naylor, J. Mieure, W. Adams, J. Weeks, F. Castaldi, L. Ogle, R. Romano (1992)
Alkylphenol ethoxylates in the environmentJournal of the American Oil Chemists Society, 69
Catherine Harris, P. Henttu, M. Parker, J. Sumpter (1997)
The estrogenic activity of phthalate esters in vitro.Environmental Health Perspectives, 105
D. Klotz, Barbara Beckman, Steven Hill, John Mclachlan, Marian Walters, S. Arnold (1996)
Identification of environmental chemicals with estrogenic activity using a combination of in vitro assays.Environmental Health Perspectives, 104
L. Folmar, N. Denslow, Vijayasri Rao, M. Chow, D. Crain, J. Enblom, J. Marcino, L. Guillette (1996)
Vitellogenin induction and reduced serum testosterone concentrations in feral male carp (Cyprinus carpio) captured near a major metropolitan sewage treatment plant.Environmental Health Perspectives, 104
D. Bennie (1999)
Review of the environmental occurrence of alkylphenols and alkylphenol ethoxylatesWater Quality Research Journal of Canada, 34
(1999)
The Japanese medaka (Oryzias latipes): An in vivo model for assessing the impacts of aquatic contaminants on the reproductive success of fish
C. Desbrow, E. Routledge, G. Brighty, J. Sumpter, M. Waldock (1998)
Identification of Estrogenic Chemicals in STW Effluent. 1. Chemical Fractionation and in Vitro Biological ScreeningEnvironmental Science & Technology, 32
A. Nimrod, W. Benson (1996)
Environmental estrogenic effects of alkylphenol ethoxylates.Critical reviews in toxicology, 26 3
M. Gray, K. Teather, C. Metcalfe (1999)
Reproductive success and behavior of Japanese medaka (Oryzias latipes) exposed to 4‐tert‐octylphenolEnvironmental Toxicology and Chemistry, 18
J. Harries, D. Sheahan, S. Jobling, P. Matthiessen, P. Neall, J. Sumpter, T. Tylor, N. Zaman (1997)
Estrogenic activity in five United Kingdom rivers detected by measurement of vitellogenesis in caged male troutEnvironmental Toxicology and Chemistry, 16
R. Sharpe, J. Fisher, M. Millar, S. Jobling, J. Sumpter (1995)
Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.Environmental Health Perspectives, 103
R. Herman, H. Kincaid (1988)
Pathological effects of orally administered estradiol to rainbow troutAquaculture, 72
Toki-o Yamamoto (1958)
Artificial induction of functional sex-reversal in genotypic females of the medaka (Oryzias latipes).The Journal of experimental zoology, 137 2
T. Ternes, M. Stumpf, Juergen Mueller, K. Haberer, R. Wilken, M. Servos (1999)
Behavior and occurrence of estrogens in municipal sewage treatment plants--I. Investigations in Germany, Canada and Brazil.The Science of the total environment, 225 1-2
A. Marcomini, A. Corcia, R. Samperi, S. Capri (1993)
Reversed-phase high-performance liquid chromatographic determination of linear alkylbenzene sulphonates, nonylphenol polyethoxylates and their carboxylic biotransformation productsJournal of Chromatography A, 644
Bennett Bennett, Metcalfe Metcalfe (2000)
The distribution of degradation products of alkylphenol ethoxylates near sewage treatment plants in the lower Great LakesEnviron Toxicol Chem, 19
Gonadal intersex and high prevalences of the female phenotype have been observed in fish populations in urbanized areas. Environmental estrogens discharged in sewage treatment plant effluents may be responsible for feminization of fish but many compounds with the potential to induce these responses occur in effluents, including natural and synthetic estrogen hormones, degradation products of alkylphenol ethoxylate surfactants, and plasticizers. In this study, the estrogen hormones 17α‐ethinylestradiol, 17β‐estradiol, estrone, and estriol induced intersex (i.e., testis‐ova) and altered sex in Japanese medaka (Oryzias latipes) when these fish were exposed to nanogram per liter concentrations of test compounds from hatch to approximately 100 d after hatch. A mix of nonylphenol mono‐ and diethoxylate induced a weak response and a mix of nonylphenol mono‐ and diethoxycarboxylate did not give a response in this assay at microgram per liter concentrations, indicating that these degradation products of nonylphenol ethoxylates have little or no estrogenic activity in fish. Bisphenol A induced testis‐ova in medaka exposed to a concentration of 10 μg/L, but diethylhexyl phthalate did not induce a response. Results with the medaka assay were consistent with estrogenic responses in the yeast estrogen screening assay. Analyses of monitoring data reported in the literature indicate that concentrations of estrogen hormones detected in the final effluents of sewage treatment plants are generally greater than the lowest‐observed‐effect levels for alterations to gonadal development in medaka.
Environmental Toxicology & Chemistry – Wiley
Published: Feb 1, 2001
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.