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Baranski Bg, Young Ns (1988)
Autoimmune aspects of aplastic anemia.in Vivo, 2
M. Anderson, P. Higgins, L. Davis, J. Willman, S. Jones, I. Kidd, J. Pattison, D. Tyrrell (1985)
Experimental Parvoviral Infection in HumansThe Journal of Infectious Diseases, 152
N. Young, M. Harrison, J. Moore, P. Mortimer, R. Humphries (1984)
Direct demonstration of the human parvovirus in erythroid progenitor cells infected in vitro.The Journal of clinical investigation, 74 6
D. Pardi, Y. Romero, L. Mertz, D. Douglas (1998)
HEPATITIS-ASSOCIATED APLASTIC ANEMIA AND ACUTE PARVOVIRUS B19 INFECTION: A REPORT OF TWO CASES AND A REVIEW OF THE LITERATUREAmerican Journal of Gastroenterology, 93
C. Potter, A. Potter, C. Hatton, H. Chapel, M., J., Anderson, R. Pattison, J. D.A., Tyrrell, P., G., Higgins, S. Willman, F. H., Parry (1987)
Variation of erythroid and myeloid precursors in the marrow and peripheral blood of volunteer subjects infected with human parvovirus (B19).The Journal of clinical investigation, 79 5
A. Langnas, R. Markin, M. Cattral, S. Naides (1995)
Parvovirus B19 as a possible causative agent of fulminant liver failure and associated aplastic anemiaHepatology, 22
Y. Bertrand, J. Lefrère, G. Leverger, Couroucé Am, C. Féo, M. Clark, G. Schaison, J. Soulier (1985)
AUTOIMMUNE HAEMOLYTIC ANAEMIA REVEALED BY HUMAN PARVOVIRUS LINKED ERYTHROBLASTOPENIAThe Lancet, 326
S. Rosenfeld, J. Kimball, D. Vining, N. Young (1995)
Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia.Blood, 85 11
G. Kurtzman, K. Ozawa, B. Cohen, G. Hanson, R. Oseas, N. Young (1987)
Chronic bone marrow failure due to persistent B19 parvovirus infection.The New England journal of medicine, 317 5
S. Gillespie, M. Cartter, S. Asch, James Rokos, G. Gary, Cecelia Tsou, D. Hall, L. Anderson, E. Hurwitz (1990)
Occupational risk of human parvovirus B19 infection for school and day-care personnel during an outbreak of erythema infectiosum.JAMA, 263 15
G. Kurtzman, N. Young (1989)
4 Viruses and bone marrow failureBaillière's clinical haematology, 2
Clewley Jp (1985)
Detection of human parvovirus using a molecularly cloned probe.Journal of Medical Virology, 15
P. Mortimer, B. Cohen, M. Buckley, J. Cradock-Watson, MargaretK. Ridehalgh, F. Burkhardt, U. Schilt (1985)
HUMAN PARVOVIRUS AND THE FETUSThe Lancet, 326
H. Shichino, H. Mugishima, M. Takamura, T. Shimada, Takashi Suzuki, M. Chin, K. Harada, S. Ryo, S. Kojima (1996)
Treatment of aplastic anemia with antithymocyte globulin, cyclosporin A, methylprednisolone, danazole and recombinant human granulocyte‐colony stimulating factorPediatrics International, 38
M. Hamon, A. Newland, M. Anderson (1988)
Severe aplastic anaemia after parvovirus infection in the absence of underlying haemolytic anaemia.Journal of Clinical Pathology, 41
Human parvovirus B19 (B19 virus) infection is known to induce aplastic crisis in patients with hemolytic anemia. In healthy subjects, B19 infection may sometimes cause mild pancytopenia, but these changes are transient and recovery is spontaneous. We report the first case of aplastic anemia in a previously healthy boy without any underlying diseases, following asymptomatic infection with the B19 virus. Laboratory examination initially showed thrombocytopenia, mild leukopenia in the peripheral blood, and severe hypoplastic bone marrow. Since pancytopenia developed and worsened progressively, immunosuppressive therapy was given, resulting in a complete remission. Despite the lack of an infectious prodrome, serological and histological analysis revealed an underlying infection with the B19 virus. Thus, B19 virus infection must be considered one of the causes of aplastic anemia in patients without underlying hemolytic anemia and an apparent episode of the viral infection.
Annals of Hematology – Springer Journals
Published: Feb 1, 1999
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