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H. Milani, R. Schwarting, S. Kumpf, H. Steiner, J. Huston (1990)
Interaction between recovery from behavioral asymmetries induced by hemivibrissotomy in the rat and the effects of apomorphine and amphetamine.Behavioral neuroscience, 104 3
K. Franklin, Joanne Wolfe (1987)
Opposed locomotor asymmetries following lesions of the medial and lateral substantia nigra pars compacta or pars reticulata in the ratPhysiology & Behavior, 40
K. Neve, C. Altar, Catherine Wong, J. Marshall (1984)
Quantitative analysis of [3H]spiroperidol binding to rat forebrain sections: Plasticity of neostriatal dopamine receptors after nigrostriatal injuryBrain Research, 302
Joseph Huston, H. Steiner, H. Weiler, S. Morgan, Rainer Schwarting (1990)
The basal ganglia-orofacial system: Studies on neurobehavioral plasticity and sensory-motor tuningNeuroscience & Biobehavioral Reviews, 14
J. McDevitt, P. Setler (1980)
Dopaminergic effects of lergotrile: Possible involvement of a metaboliteNeuropharmacology, 19
Yves Agid, F. Javoy, Jacques Glowinski (1973)
Hyperactivity of remaining dopaminergic neurones after partial destruction of the nigro-striatal dopaminergic system in the rat.Nature: New biology, 245 144
M. Ziegler, H. Szechtman (1988)
Differences in the behavioral profile of circling under amphetamine and apomorphine in rats with unilateral lesions of the substantia nigra.Behavioral neuroscience, 102 2
M. Caligiuri, J. Abbs (1987)
Response properties of the perioral reflex in parkinson's diseaseExperimental Neurology, 98
W. Graham, A. Crossman, G. Woodruff (1990)
Autoradiographic studies in animal models of hemi-parkinsonism reveal dopamine D2 but not D1 receptor supersensitivity. I. 6-OHDA lesions of ascending mesencephalic dopaminergic pathways in the ratBrain Research, 514
J. Schneider, S. Diamond, C. Markham (1986)
Deficits in orofacial sensorimotor function in Parkinson's diseaseAnnals of Neurology, 19
Kehr Kehr, Carlsson Carlsson, Lindqvist Lindqvist, Magnusson Magnusson, Atack Atack (1972)
Evidence for a receptor‐mediated feedback control of tyrosine hydroxylase activityJ. Pharm. Pharmacol., 24
S. Lavielle, J. Tassin, A. Thierry, G. Blanc, D. Hervé, C. Barthélémy, J. Glowinski (1979)
Blockade by benzodiazepines of the selective high increase in dopamine turnover induced by stress in mesocortical dopaminergic neurons of the ratBrain Research, 168
M. Pucak, A. Grace (1991)
Partial dopamine depletions result in an enhanced sensitivity of residual dopamine neurons to apomorphineSynapse, 9
G. Breese, G. Duncan, T. Napier, S. Bondy, L. Iorio, R. Mueller (1987)
6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.The Journal of pharmacology and experimental therapeutics, 240 1
A. Imperato, G. Chiara (1988)
Effects of locally applied D-1 and D-2 receptor agonists and antagonists studied with brain dialysis.European journal of pharmacology, 156 3
T. Zetterström, T. Sharp, U. Ungerstedt (1986)
Further evaluation of the mechanism by which amphetamine reduces striatal dopamine metabolism: a brain dialysis study.European journal of pharmacology, 132 1
C. Altar, M. Marien, J. Marshall (1987)
Time Course of Adaptations in Dopamine Biosynthesis, Metabolism, and Release Following Nigrostriatal Lesions: Implications for Behavioral Recovery from Brain InjuryJournal of Neurochemistry, 48
Leon Thal, R. Mishra, E. Gardner, S. Horowitz, Susannah Varmuza, M. Makman (1979)
Dopamine antagonist binding increases in two behaviorally distinct striatal denervation syndromesBrain Research, 170
B. Mileson, Mark Lewis, R. Mailman (1991)
Dopamine receptor ‘supersensitivity’ occurring without receptor up-regulationBrain Research, 561
N. Ozaki, D. Nakahara, H. Miura, Y. Kasahara, T. Nagatsu (1989)
Effects of Apomorphine on In Vivo Release of Dopamine and Its Metabolites in the Prefrontal Cortex and the Striatum, Studied by a Microdialysis MethodJournal of Neurochemistry, 53
Bernheimer Bernheimer, Birkmayer Birkmayer, Hornykiewicz Hornykiewicz, Jellinger Jellinger, Seitelbergger Seitelbergger (1973)
Brain dopamine and the syndromes of Parkinson and HuntingtonJ. Neurol. Sci., 20
H. Steiner, J. Huston, S. Morgan (1986)
Apomorphine reverses direction of asymmetry in facial scanning after 10 days of unilateral vibrissae removal in rat: Vibrissotomy-induced denervation supersensitivity?Behavioural Brain Research, 22
H. Bernheimer, W. Birkmayer, O. Hornykiewicz, K. Jellinger, F. Seitelberger (1973)
Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations.Journal of the neurological sciences, 20 4
A. Bonatz, H. Steiner, J. Huston (1987)
Video image analysis of behavior by microcomputer: categorization of turning and locomotion after 6-OHDA injection into the substantia nigraJournal of Neuroscience Methods, 22
S. Wachtel, Xiu-Ti Hu, M. Galloway, F. White (1989)
D1 dopamine receptor stimulation enables the postsynaptic, but not autoreceptor, effects of D2 dopamine agonists in nigrostriatal and mesoaccumbens dopamine systemsSynapse, 4
R. Mattioli, R. Schwarting, J. Huston (1992)
Recovery from unilateral 6-hydroxydopamine lesion of substantia nigra promoted by the neurotachykinin substance P1–11Neuroscience, 48
T. Robinson, E. Castañeda, I. Whishaw (1990)
Compensatory changes in striatal dopamine neurons following recovery from injury induced by 6-OHDA or methamphetamine: a review of evidence from microdialysis studies.Canadian journal of psychology, 44 2
R. Schwarting, J. Huston (1987)
Short-term effects of ether, equithesin and droperidol/fentanyl on catecholamine and indolamine metabolism in the brain of the ratNeuropharmacology, 26
P. Groves, C. Wilson, S. Young, G. Rebec (1975)
Self-inhibition by dopaminergic neuronsScience, 190
W. Kehr, A. Carlsson, M. Lindqvist, T. Magnusson, C. Atack (1972)
Evidence for a receptor‐mediated feedback control of striatal tyrosine hydroxylase activityJournal of Pharmacy and Pharmacology, 24
T. Nagatsu (1988)
[Biochemistry of Parkinson's disease].Seikagaku. The Journal of Japanese Biochemical Society, 60 5
U. Ungerstedt, G. Arbuthnott (1970)
Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system.Brain research, 24 3
G. Paxinos, Charles Watson (1983)
The Rat Brain in Stereotaxic Coordinates
R. Mandel, P. Randall (1990)
Bromocriptine-induced rotation: Characterization using a striatal efferent lesion in the mouseBrain Research Bulletin, 24
Miller Miller, Beninger Beninger (1991)
On the interpretation of asymmetries of posture and locomotion produced with dopamineProg. Neurobiol., 36
R. Schwarting, J. Huston (1992)
Behavioral concomitants of regional changes in the brain's biogenic amines after apomorphine and amphetaminePharmacology Biochemistry and Behavior, 41
D. Zahm (1991)
Compartments in rat dorsal and ventral striatum revealed following injection of 6-hydroxydopamine into the ventral mesencephalonBrain Research, 552
L. Ståhle, U. Ungerstedt (1986)
Different behavioural patterns induced by the dopamine agonist apomorphine analysed by multivariate statisticsPharmacology Biochemistry and Behavior, 24
I. Creese, D. Burt, D. Burt, SolomonH Snyder (1977)
Dopamine receptor binding enhancement accompanies lesion-induced behavioral supersensitivity.Science, 197 4303
O. Gershanik, R. Heikkila, R. Duvoisin (1983)
Effects of dopamine depletion on rotational behavior to dopamine agonistsBrain Research, 261
F. Hefti, E. Melamed, R. Wurtman (1980)
Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterizationBrain Research, 195
Robert Miller, R. Beninger (1991)
On the interpretation of asymmetries of posture and locomotion produced with dopamine agonists in animals with unilateral depletion of striatal dopamineProgress in Neurobiology, 36
M. Zigmond, E. Abercrombie, T. Berger, A. Grace, E. Stricker (1990)
Compensations after lesions of central dopaminergic neurons: some clinical and basic implicationsTrends in Neurosciences, 13
(1983)
Biochemical actions of amphetamine and other stimulants. In: Creese I (Ed.) Stimulants: Neurochemical, behavioral, and clinical perspectives
B. Costall, C. Marsden, R. Naylor, C. Pycock (1976)
The relationship between striatal and mesolimbic dopamine dysfunction and the nature of circling responses following 6-hydroxydopamine and electrolytic lesions of the ascending dopamine systems of rat brainBrain Research, 118
R. Schwarting, A. Bonatz, R. Carey, J. Huston (1991)
Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injectionsBrain Research, 554
R. Schwarting, J. Huston (1987)
Dopamine and Serotonin Metabolism in Brain Sites Ipsi‐ and Contralateral to Direction of Conditioned Turning in RatsJournal of Neurochemistry, 48
B. Bunney, J. Walters, R. Roth, G. Aghajanian (1973)
Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.The Journal of pharmacology and experimental therapeutics, 185 3
U. Ungerstedt (1971)
Postsynaptic supersensitivity after 6-hydroxy-dopamine induced degeneration of the nigro-striatal dopamine system.Acta physiologica Scandinavica. Supplementum, 367
W. Spirduso, P. Gilliam, T. Schallert, M. Upchurch, D. Vaughn, R. Wilcox (1985)
Reactive capacity: A sensitive behavioral marker of movement initiation and nigrostriatal dopamine functionBrain Research, 335
D. Calne, J. Langston (1983)
AETIOLOGY OF PARKINSON'S DISEASEThe Lancet, 322
O. Giorgi, G. Biggio (1990)
Unilateral inactivation of dopamine receptors after intrastriatal injection of N-ethoxy-carbonyl-2- ethoxy-1,2-dihydroquinoline (EEDQ): A novel rotational model to investigate dopamine receptor interactionsPharmacology Biochemistry and Behavior, 35
C. Altar, M. Marien (1989)
Preservation of dopamine release in the denervated striatumNeuroscience Letters, 96
M. Geyer, P. Russo, D. Segal, R. Kuczenski (1987)
Effects of apomorphine and amphetamine on patterns of locomotor and investigatory behavior in ratsPharmacology Biochemistry and Behavior, 28
A. Carlsson, M. Lindqvist (2009)
EFFECT OF CHLORPROMAZINE OR HALOPERIDOL ON FORMATION OF 3METHOXYTYRAMINE AND NORMETANEPHRINE IN MOUSE BRAIN.Acta pharmacologica et toxicologica, 20
H. Steiner, A. Bonatz, J. Huston, R. Schwarting (1988)
Lateralized wall-facing versus turning as measures of behavioral asymmetries and recovery of function after injection of 6-hydroxydopamine into the substantia nigraExperimental Neurology, 99
Asymmetries in turning and scanning were investigated in rats with different degrees of neostriatal dopamine depletion after unilateral injections of 6‐hydroxydopamine into the substantia nigra. Animals with severe lesions, i. e., residual dopamine levels of <20%, spontaneously turned ipsiversive and showed more scanning behavior with the side ipsilateral to the lesion. These asymmetries were reversed by the dopamine receptor agonist apomorphine. Animals with less severe dopamine depletion, i. e., residual dopamine levels of 20–65%, did not show an asymmetry in spontaneous turning, but an ipsilateral asymmetry in scanning was still observed, indicating a greater sensitivity of this measure for moderate striatal dopamine depletions. Furthermore, in animals with residual dopamine levels of 45–65%, the dopamine receptor agonist apomorphine did not lead to a behavioral reversal as with severe lesions, but induced ipsilateral scanning and ipsiversive turning. These ipsiversive asymmetries are discussed in relation to asymmetries in self‐regulatory mechanisms of the nigro‐striatal dopamine system, such as dopamine autoreceptors controlling the release of this transmitter. Dopamine receptor‐stimulated behavioral asymmetry in animals with moderate depletions of dopamine is suggested as a preclinical model to study mechanisms affected in the early state of Parkinson's disease. © 1993 Wiley‐Liss, Inc.
Synapse – Wiley
Published: Feb 1, 1993
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