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Simulated public speaking as a model of clinical anxiety

Simulated public speaking as a model of clinical anxiety 213 77 77 1 1 Douglas M. McNair Laura M. Frankenthaler Thomas Czerlinsky Thomas W. White Stephen Sasson Seymour Fisher Clinical Psychopharmacology Laboratory, Department of Psychology Boston University 64 Cummington Street 02215 Boston MA USA Stout Vocational and Rehabilitation Institute University of Wisconsin 54751 Menomonie WI USA Department of Pharmacology Boston University Medical Center 02118 Boston MA USA Department of Psychiatry University of Texas Medical Branch 77550 Galveston TX USA Abstract Normal male volunteers took single acute doses of either diazepam or placebo under double-blind conditions in three simulated public speaking experiments. Measures of palmar sweating and subjective anxiety showed that anticipation of speaking in public increased anxiety relative to baseline and prestress conditions, and performance of public speaking further increased anxiety. A dose-related anxiolytic effect of diazepam on subjective anxiety supported the model's clinical relevance. Moreover, the intensity of the subject's public speaking phobia predicted both degree of prestress anxiety relief from 10 mg diazepam and overall anxiety level, regardless of medication, throughout the experimental session. A measure of traditionalism predicted placebo and 5 mg diazepam response during prestress: As in previous clinical trials, high traditionalism scorers reported more relief from placebo, whereas low scorers showed more relief from diazepam. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychopharmacology Springer Journals

Simulated public speaking as a model of clinical anxiety

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References (18)

Publisher
Springer Journals
Copyright
Copyright © 1982 by Springer-Verlag
Subject
Biomedicine; Pharmacology/Toxicology; Psychiatry
ISSN
0033-3158
eISSN
1432-2072
DOI
10.1007/BF00436092
Publisher site
See Article on Publisher Site

Abstract

213 77 77 1 1 Douglas M. McNair Laura M. Frankenthaler Thomas Czerlinsky Thomas W. White Stephen Sasson Seymour Fisher Clinical Psychopharmacology Laboratory, Department of Psychology Boston University 64 Cummington Street 02215 Boston MA USA Stout Vocational and Rehabilitation Institute University of Wisconsin 54751 Menomonie WI USA Department of Pharmacology Boston University Medical Center 02118 Boston MA USA Department of Psychiatry University of Texas Medical Branch 77550 Galveston TX USA Abstract Normal male volunteers took single acute doses of either diazepam or placebo under double-blind conditions in three simulated public speaking experiments. Measures of palmar sweating and subjective anxiety showed that anticipation of speaking in public increased anxiety relative to baseline and prestress conditions, and performance of public speaking further increased anxiety. A dose-related anxiolytic effect of diazepam on subjective anxiety supported the model's clinical relevance. Moreover, the intensity of the subject's public speaking phobia predicted both degree of prestress anxiety relief from 10 mg diazepam and overall anxiety level, regardless of medication, throughout the experimental session. A measure of traditionalism predicted placebo and 5 mg diazepam response during prestress: As in previous clinical trials, high traditionalism scorers reported more relief from placebo, whereas low scorers showed more relief from diazepam.

Journal

Psychopharmacology – Springer Journals

Published: May 1, 1982

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