Access the full text.
Sign up today, get DeepDyve free for 14 days.
Loading next page...
/lp/wiley/atopic-and-non-atopic-allergic-disorders-current-insights-into-the-GGJpxL07hm
References (125)
-
P. Schmid, D. Simon, H. Simon, C. Akdis, B. Wüthrich (2001)
Epidemiology, clinical features, and immunology of the “intrinsic” (non‐IgE‐mediated) type of atopic dermatitis (constitutional dermatitis)Allergy, 56
-
S. Presslauer, D. Milosavljevic, T. Brücke, P. Bayer, W. Hübl (2008)
Elevated levels of kappa free light chains in CSF support the diagnosis of multiple sclerosisJournal of Neurology, 255
-
V. Lund (1995)
INTERNATIONAL CONSENSUS REPORT ON THE DIAGNOSIS AND MANAGEMENT OF RHINITIS - PREFACERevue Francaise D Allergologie
-
M. Chehade (2007)
IgE and non-IgE-mediated food allergy: treatment in 2007Current Opinion in Allergy and Clinical Immunology, 7
-
R. Settipane, P. Lieberman (2001)
Update on nonallergic rhinitis.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 86 5
-
Nakano Nakano, Takahashi Takahashi, Miyazaki Miyazaki (2006)
Antigen‐specific free immunoglobulin light‐chain antibodiescould it be a new diagnostic marker for patients with allergy?, 39
-
M. Heijden, A. Kraneveld, F. Redegeld (2006)
Free immunoglobulin light chains as target in the treatment of chronic inflammatory diseases.European journal of pharmacology, 533 1-3
-
H. Gould, B. Sutton (2008)
IgE in allergy and asthma todayNature Reviews Immunology, 8
-
D. Powe, C. Jagger, A. KleinJan, Andrew Carney, D. Jenkins, Nick Jones (2003)
‘Entopy’: localized mucosal allergic disease in the absence of systemic responses for atopyClinical & Experimental Allergy, 33
-
Katzmann Katzmann, Clark Clark, Abraham Abraham (2002)
Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chainsrelative sensitivity for detection of monoclonal light chains, 48
-
L. Smurthwaite, Samantha Walker, Duncan Wilson, Diana S. Birch, T. Merrett, S. Durham, H. Gould (2001)
Persistent IgE synthesis in the nasal mucosa of hay fever patientsEuropean Journal of Immunology, 31
-
S. Salvi, K. Babu (2000)
Treatment of allergic asthma with monoclonal anti-IgE antibody.The New England journal of medicine, 342 17
-
H. Saito (2005)
Much Atopy about the Skin: Genome-Wide Molecular Analysis of Atopic EczemaInternational Archives of Allergy and Immunology, 137
-
Daniel Navi, J. Saegusa, Fu-Tong Liu (2007)
Mast Cells and Immunological Skin DiseasesClinical Reviews in Allergy & Immunology, 33
-
M. Shaker, D. Woodmansee (2009)
An update on food allergyCurrent Opinion in Pediatrics, 21
-
L. Chen, L. Overbergh, C. Mathieu, L. Chan (2008)
The development of atopic dermatitis is independent of Immunoglobulin E up‐regulation in the K14‐IL‐4 SKH1 transgenic mouse modelClinical & Experimental Allergy, 38
-
Eigenmann (2007)
The spectrum of cow's milk allergy. Pediatric allergy and immunology, 18
-
M. Rottem (2010)
[Allergic rhinitis and its impact on asthma].Harefuah, 149 6
-
S. Bloomfield, R. Stanwell‐Smith, R. Crevel, J. Pickup (2006)
Too clean, or not too clean: the Hygiene Hypothesis and home hygieneClinical and Experimental Allergy, 36
-
S. Galli, M. Tsai (2008)
Mast cells: versatile regulators of inflammation, tissue remodeling, host defense and homeostasis.Journal of dermatological science, 49 1
-
M. Humbert, S. Durham, P. Kimmitt, N. Powell, B. Assoufi, R. Pfister, G. Menz, A. Kay, C. Corrigan (1997)
Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma.The Journal of allergy and clinical immunology, 99 5
-
M. Humbert, R. Beasley, J. Ayres, R. Slavin, J. Hebert, J. Bousquet, K. Beeh, S. Ramos, G. Canonica, S. Hedgecock, H. Fox, M. Blogg, K. Surrey (2005)
Benefits of omalizumab as add‐on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATEAllergy, 60
-
J. Rijswijk, H. Blom, W. Fokkens (2005)
Idiopathic rhinitis, the ongoing questAllergy, 60
-
E. Brenninkmeijer, P. Spuls, Catharina Legierse, R. Lindeboom, J. Smitt, J. Bos (2008)
Clinical differences between atopic and atopiform dermatitis.Journal of the American Academy of Dermatology, 58 3
-
Bloomfield (2006)
Too clean, or not too clean, 36
-
K. Huggins, J. Brostoff (1975)
LOCAL PRODUCTION OF SPECIFIC IgE ANTIBODIES IN ALLERGIC-RHINITIS PATIENTS WITH NEGATIVE SKIN TESTSThe Lancet, 306
-
A. Zacharasiewicz, J. Douwes, N. Pearce (2003)
What proportion of rhinitis symptoms is attributable to atopy?Journal of clinical epidemiology, 56 4
-
Carney Carney, Powe Powe, Huskisson Huskisson, Jones Jones (2002)
Atypical nasal challenges in patients with idiopathic rhinitis?more evidence for the existence of allergy in the absence of atopy, 32
-
J. Bousquet, P. Cabrera, N. Berkman, R. Buhl, S. Holgate, S. Wenzel, H. Fox, S. Hedgecock, M. Blogg, G. Cioppa (2005)
The effect of treatment with omalizumab, an anti‐IgE antibody, on asthma exacerbations and emergency medical visits in patients with severe persistent asthmaAllergy, 60
-
(2008)
Increase in immunoglobulin free light chains in children with atopic dermatitis -
Els Truyen, Liesbeth Coteur, E. Dilissen, L. Overbergh, L. Dupont, J. Ceuppens, D. Bullens (2006)
Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patientsThorax, 61
-
A. Hannam-Harris, J. Smith (1981)
Induction of balanced immunoglobulin chain synthesis in free light chain-producing lymphocytes by mitogen stimulation.Journal of immunology, 126 5
-
Rijnierse Rijnierse, Redegeld Redegeld, Van Der Heiden Van Der Heiden, Blokhuis Blokhuis, Nijkamp Nijkamp, Kraneveld Kraneveld (2005)
Immunoglobulin free light chaina new immunological factor in IBD, 128
-
R. Pawankar, C. Baena-Cagnani, J. Bousquet, G. Canonica, Á. Cruz, M. Kaliner, B. Lanier (2008)
State of World Allergy Report 2008: Allergy and Chronic Respiratory DiseasesThe World Allergy Organization Journal, 1
-
Humbert Humbert, Menz Menz, Ying Ying (1999)
The immunopathology of extrinsic (atopic) and intrinsic (non‐atopic) asthmamore similarities than differences, 20
-
Powe Powe, Jagger Jagger, Kleinjan Kleinjan, Carney Carney, Jenkins Jenkins, Jones Jones (2003)
‘Entopy’localized mucosal allergic disease in the absence of systemic responses for atopy, 33
-
Henk Blom, T. Godthelp, W. Fokkens, A. Jan, P. Mulder, E. Rijntjes (1997)
The effect of nasal steroid aqueous spray on nasal complaint scores and cellular infiltrates in the nasal mucosa of patients with nonallergic, noninfectious perennial rhinitis.The Journal of allergy and clinical immunology, 100 6 Pt 1
-
N. Pearce, J. Douwes, R. Beasley (2000)
Is allergen exposure the major primary cause of asthma?Thorax, 55
-
C. Brightling, P. Bradding, F. Symon, S. Holgate, A. Wardlaw, I. Pavord (2002)
Mast-cell infiltration of airway smooth muscle in asthma.The New England journal of medicine, 346 22
-
Marc Humbert, J. Grant, Luís Taborda-Barata, S. Durham, R. Pfister, G. Menz, J. Barkans, Sun Ying, A. Kay (1996)
High-affinity IgE receptor (FcepsilonRI)-bearing cells in bronchial biopsies from atopic and nonatopic asthma.American journal of respiratory and critical care medicine, 153 6 Pt 1
-
H. Alenius, D. Laouini, A. Woodward, E. Mizoguchi, A. Bhan, E. Castigli, H. Oettgen, R. Geha (2002)
Mast cells regulate IFN-gamma expression in the skin and circulating IgE levels in allergen-induced skin inflammation.The Journal of allergy and clinical immunology, 109 1
-
Galli (2008)
Mast cells, 49
-
Eckard Hamelmann, Gregory Cieslewicz, J. Schwarze, Tamotsu Ishizuka, A. Joetham, C. Heusser, Erwin Gelfand (1999)
Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness.American journal of respiratory and critical care medicine, 160 3
-
W. Obara, Y. Kawa, C. Ra, K. Nishioka, Y. Soma, M. Mizoguchi (2002)
T Cells and Mast Cells as a Major Source of Interleukin-13 in Atopic DermatitisDermatology, 205
-
Wenzel Wenzel (2006)
Asthmadefining of the persistent adult phenotypes, 368
-
O. Malbec, M. Daëron (2007)
The mast cell IgG receptors and their roles in tissue inflammationImmunological Reviews, 217
-
Thio Thio, Blokhuis Blokhuis, Nijkamp Nijkamp, Redegeld Redegeld (2008)
Free immunoglobulin light chainsa novel target in the therapy of inflammatory diseases, 29
-
S. Wenzel (2006)
Asthma: defining of the persistent adult phenotypesThe Lancet, 368
-
W. Fokkens (2002)
Thoughts on the pathophysiology of nonallergic rhinitisCurrent Allergy and Asthma Reports, 2
-
S. Zar, D. Kumar (2002)
Role of food hypersensitivity in irritable bowel syndrome.Minerva medica, 93 5
-
E. Mølgaard, S. Thomsen, Thomas Lund, L. Pedersen, H. Nolte, V. Backer (2007)
Differences between allergic and nonallergic rhinitis in a large sample of adolescents and adultsAllergy, 62
-
J. Bousquet, P. Jeffery, W. Busse, Malcolm Johnson, A. Vignola (2000)
Asthma. From bronchoconstriction to airways inflammation and remodeling.American journal of respiratory and critical care medicine, 161 5
-
B. Leynaert, J. Bousquet, C. Neukirch, R. Liard, F. Neukirch (1999)
Perennial rhinitis: An independent risk factor for asthma in nonatopic subjects: results from the European Community Respiratory Health Survey.The Journal of allergy and clinical immunology, 104 2 Pt 1
-
S. Ying, Marc Humbert, J. Barkans, Christopher Corrigan, R. Pfister, G. Menz, M. Larché, D. Robinson, S. Durham, A. Kay (1997)
Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.Journal of immunology, 158 7
-
Takanari Nakano, Hidenori Takahashi, S. Miyazaki, S. Kawai, R. Shinozaki, T. Komoda, A. Nagata (2006)
Antigen-specific free immunoglobulin light-chain antibodies: could it be a new diagnostic marker for patients with allergy?Clinical biochemistry, 39 9
-
M. Humbert, G. Menz, S. Ying, C. Corrigan, D. Robinson, S. Durham, A. Kay (1999)
The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences.Immunology today, 20 11
-
Christoph Walker, Erhard Bode, Liesbeth Boer, T. Hansel, K. Blaser, J. Virchow (1992)
Allergic and nonallergic asthmatics have distinct patterns of T-cell activation and cytokine production in peripheral blood and bronchoalveolar lavage.The American review of respiratory disease, 146 1
-
Romain Pauwels (1996)
GLOBAL STRATEGY FOR ASTHMA MANAGEMENT AND PREVENTION, 45
-
H. Gould, B. Sutton, A. Beavil, R. Beavil, N. Mccloskey, Heather Coker, D. Fear, L. Smurthwaite (2001)
The biology of IGE and the basis of allergic disease.Annual review of immunology, 21
-
S. Sicherer, D. Leung (2004)
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2009.The Journal of allergy and clinical immunology, 125 1
-
E. Forbes, Katherine Groschwitz, J. Abonia, E. Brandt, E. Cohen, C. Blanchard, R. Ahrens, L. Seidu, A. McKenzie, R. Strait, F. Finkelman, Paul Foster, Paul Foster, K. Matthaei, M. Rothenberg, S. Hogan (2008)
IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivityThe Journal of Experimental Medicine, 205
-
Humbert Humbert, Durham Durham, Ying Ying (1996)
IL‐4 and IL‐5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthmaevidence against “intrinsic” asthma being a distinct immunopathologic entity, 154
-
Andrew Carney, D. Powe, R. Huskisson, Nick Jones (2002)
Atypical nasal challenges in patients with idiopathic rhinitis: more evidence for the existence of allergy in the absence of atopy?Clinical & Experimental Allergy, 32
-
R. Salib, Philip Harries, S. Nair, Peter Howarth (2008)
Mechanisms and mediators of nasal symptoms in non‐allergic rhinitisClinical & Experimental Allergy, 38
-
A. Jayaratnam, Christopher Corrigan, Tak Lee (2005)
The continuing enigma of non‐atopic asthmaClinical & Experimental Allergy, 35
-
A. KleinJan, J. Vinke, L. Severijnen, W. Fokkens (2000)
Local production and detection of (specific) IgE in nasal B-cells and plasma cells of allergic rhinitis patients.The European respiratory journal, 15 3
-
E. Bateman, S. Hurd, P. Barnes, J. Bousquet, J. Drazen, J. FitzGerald, P. Gibson, K. Ohta, P. O'Byrne, S. Pedersen, E. Pizzichini, S. Sullivan, S. Wenzel, H. Zar (2008)
Global strategy for asthma management and prevention: GINA executive summaryEuropean Respiratory Journal, 31
-
W. Ying, P. Sanders (2001)
Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall protein.The American journal of pathology, 158 5
-
D. Powe, R. Huskisson, Andrew Carney, D. Jenkins, Nick Jones (2001)
Evidence for an inflammatory pathophysiology in idiopathic rhinitisClinical & Experimental Allergy, 31
-
A. Bentley, G. Menz, C. Storz, D. Robinson, B. Bradley, P. Jeffery, S. Durham, A. Kay (1992)
Identification of T lymphocytes, macrophages, and activated eosinophils in the bronchial mucosa in intrinsic asthma. Relationship to symptoms and bronchial responsiveness.The American review of respiratory disease, 146 2
-
M. Thio, B. Blokhuis, F. Nijkamp, F. Redegeld (2008)
Free immunoglobulin light chains: a novel target in the therapy of inflammatory diseases.Trends in pharmacological sciences, 29 4
-
H. Blom, T. Godthelp, W. Fokkens, A. Jan, A. Holm, Thea Vroom, E. Rijntjes (2006)
Mast cells, eosinophils and IgE-positive cells in the nasal mucosa of patients with vasomotor rhinitis An immunohistochemical studyEuropean Archives of Oto-Rhino-Laryngology, 252
-
S. Ying, M. Humbert, Q. Meng, R. Pfister, G. Menz, H. Gould, A. Kay, S. Durham (2001)
Local expression of ϵ germline gene transcripts and RNA for the ϵ heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthmaThe Journal of Allergy and Clinical Immunology, 107
-
P. Barnes, I. Adcock (2003)
How Do Corticosteroids Work in Asthma?Annals of Internal Medicine, 139
-
S. Ying, Q. Meng, K. Zeibecoglou, D. Robinson, A. Macfarlane, M. Humbert, A. Kay (1999)
Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 (MCP-3), and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (Intrinsic) asthmatics.Journal of immunology, 163 11
-
Mang Yu, M. Tsai, S. Tam, Carol Jones, J. Zehnder, S. Galli (2006)
Mast cells can promote the development of multiple features of chronic asthma in mice.The Journal of clinical investigation, 116 6
-
H. Oettgen, T. Martin, A. Wynshaw-Boris, C. Deng, J. Drazen, P. Leder (1994)
Active anaphylaxis in IgE-deficient miceNature, 370
-
A. Shapiro, M. Scharff, J. Maizel, J. Uhr (1966)
Synthesis of Excess Light Chains of Gamma Globulin by Rabbit Lymph Node CellsNature, 211
-
Chehade (2007)
IgE and non-IgE-mediated food allergy, 7
-
Leynaert Leynaert, Bousquet Bousquet, Neukirch Neukirch, Liard Liard, Neukirch Neukirch (1999)
Perennial rhinitisan independent risk factor for asthma in nonatopic subjects: results from the European Community Respiratory Health Survey, 104
-
A. Togias (2003)
Rhinitis and asthma: evidence for respiratory system integration.The Journal of allergy and clinical immunology, 111 6
-
J. Grossman (1997)
One airway, one disease.Chest, 111 2 Suppl
-
S. Bock (1987)
Prospective appraisal of complaints of adverse reactions to foods in children during the first 3 years of life.Pediatrics, 79 5
-
Runa Ali, Barry Kay, Professor Kay (2007)
Airway hyperresponsiveness and bronchial mucosal inflammation in T cell peptide-induced asthmatic reactions in atopic subjectsThorax, 62
-
G. Rook (2007)
The hygiene hypothesis and the increasing prevalence of chronic inflammatory disorders.Transactions of the Royal Society of Tropical Medicine and Hygiene, 101 11
-
(2003)
The central role of FcepsilonRI in allergy -
S. Romanet‐Manent, D. Charpin, A. Magnan, A. Lanteaume, D. Vervloet (2002)
Allergic vs nonallergic asthma: what makes the difference?Allergy, 57
-
C. Bachert, P. Cauwenberge, J. Olbrecht, J. Schoor (2006)
Prevalence, classification and perception of allergic and nonallergic rhinitis in BelgiumAllergy, 61
-
P. Mehlhop, Matthijs Rijn, Alison Goldberg, J. Brewer, V. Kurup, Thomas Martin, Hans Oettgen (1997)
Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma.Proceedings of the National Academy of Sciences of the United States of America, 94 4
-
S. Ying, M. Humbert, Q. Meng, R. Pfister, G. Menz, H. Gould, A. Kay, S. Durham (2001)
Local expression of epsilon germline gene transcripts and RNA for the epsilon heavy chain of IgE in the bronchial mucosa in atopic and nonatopic asthma.The Journal of allergy and clinical immunology, 107 4
-
F. Redegeld, M. Heijden, M. Kool, B. Heijdra, J. Garssen, A. Kraneveld, H. Loveren, P. Roholl, T. Saito, J. Verbeek, J. Claassens, A. Koster, F. Nijkamp (2002)
Immunoglobulin-free light chains elicit immediate hypersensitivity-like responsesNature Medicine, 8
-
T. Theoharides, D. Kalogeromitros (2006)
The Critical Role of Mast Cells in Allergy and InflammationAnnals of the New York Academy of Sciences, 1088
-
E. Bardana (2004)
Immunoglobulin E‐ (IgE) and non‐IgE‐mediated reactions in the pathogenesis of atopic eczema/dermatitis syndrome (AEDS)Allergy, 59
-
A. Comi, Alberto Tedeschi, Maurizio Lorini, A. Miadonna (2007)
Novel clinical and serological aspects in non-allergic asthma.Respiratory medicine, 101 12
-
L. Horsmanhetmo, I. Harvima, A. Järvikallio, R. Harvima, A. Naukkarinen, M. Horsmanheimo (1994)
Mast cells are one major source of interleukin‐4 in atopic dermatitisBritish Journal of Dermatology, 131
-
Pooja Takhar, C. Corrigan, L. Smurthwaite, B. O'connor, S. Durham, Tak Lee, H. Gould (2007)
Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma.The Journal of allergy and clinical immunology, 119 1
-
G. Berger, A. Goldberg, D. Ophir (1997)
The Inferior Turbinate Mast Cell Population of Patients with Perennial Allergic and Nonallergic RhinitisAmerican Journal of Rhinology & Allergy, 11
-
M. Kaliner, P. Eggleston, K. Mathews (1987)
Rhinitis and asthma.JAMA, 258 20
-
N. Pearce, J. Pekkanen, R. Beasley (1999)
How much asthma is really attributable to atopy?Thorax, 54
-
S. Holgate, T. Casale, S. Wenzel, J. Bousquet, Y. Deniz, C. Reisner (2005)
The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation.The Journal of allergy and clinical immunology, 115 3
-
A. Hannam-Harris, J. Smith (1981)
Free immunoglobulin light chain synthesis by human foetal liver and cord blood lymphocytes.Immunology, 43 3
-
P. Eigenmann (2007)
The spectrum of cow's milk allergyPediatric Allergy and Immunology, 18
-
N. Novak, T. Bieber (2003)
Allergic and nonallergic forms of atopic diseases.The Journal of allergy and clinical immunology, 112 2
-
A. Kraneveld, H. Kleij, M. Kool, Anneke Houwelingen, Andrys Weitenberg, F. Redegeld, F. Nijkamp (2002)
Key role for mast cells in nonatopic asthma.Journal of immunology, 169 4
-
R. Beasley, J. Pekkanen, N. Pearce (2001)
Has the role of atopy in the development of asthma been over‐emphasized?Pediatric Pulmonology, 32
-
C. Flohr, S. Johansson, C. Wahlgren, H. Williams (2004)
How atopic is atopic dermatitis?The Journal of allergy and clinical immunology, 114 1
-
J. Rijswijk, H. Blom, A. KleinJan, Paul Mulder, E. Rijntjes, W. Fokkens (2003)
Inflammatory cells seem not to be involved in idiopathic rhinitis.Rhinology, 41 1
-
(2005)
Elicitation of allergic asthma by immunoglobulin free light chains.Proceedings of the National Academy of Sciences of the United States of America, 102 5
-
Pooja Takhar, L. Smurthwaite, Heather Coker, D. Fear, G. Banfield, V. Carr, S. Durham, H. Gould (2005)
Allergen Drives Class Switching to IgE in the Nasal Mucosa in Allergic Rhinitis1The Journal of Immunology, 174
-
M. Humbert, S. Durham, S. Ying, P. Kimmitt, J. Barkans, B. Assoufi, R. Pfister, G. Menz, D. Robinson, A. Kay, C. Corrigan (1996)
IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity.American journal of respiratory and critical care medicine, 154 5
-
A. Ditto, Kathleen Harris, J. Krasnick, Mark Miller, R. Patterson (1996)
Idiopathic anaphylaxis: a series of 335 cases.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 77 4
-
(2008)
Anti-CD25 treatment in a mouse model for cow’s milk allergy modifies the acute skin response form IgE- into Ig free light chain-dependent -
V. Lund, A. Aaronson, J. Bousquet, R. Dahl, R. Davies, R. Wijk, K. Holmberg, E. Juniper, I. Mackay, L. Malm, N. Mygind, M. Okuda, C. Ortolani, H. Schanker, S. Spector, P. Cauwenberge, Wayoff (1994)
International Consensus Report on the diagnosis and management of rhinitis. International Rhinitis Management Working Group.Allergy, 49 19 Suppl
-
S. Sicherer, D. Leung (2006)
Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects.The Journal of allergy and clinical immunology, 118 1
-
Romanet‐Manent Romanet‐Manent, Charpin Charpin, Magnan Magnan, Lanteaume Lanteaume, Vervloet Vervloet (2002)
Allergic vs nonallergic asthmawhat makes the difference?, 57
-
(2005)
Immunoglobulin free light chain: a new immunological factor in IBD -
J. Katzmann, R. Clark, R. Abraham, S. Bryant, J. Lymp, A. Bradwell, R. Kyle (2002)
Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains.Clinical chemistry, 48 9
-
J. Rinker, K. Trinkaus, A. Cross (2006)
Elevated CSF free kappa light chains correlate with disability prognosis in multiple sclerosisNeurology, 67
-
J. Gottenberg, F. Aucouturier, J. Goetz, C. Sordet, I. Jahn, M. Busson, J. Cayuela, J. Sibilia, X. Mariette (2006)
Serum immunoglobulin free light chain assessment in rheumatoid arthritis and primary Sjögren’s syndromeAnnals of the Rheumatic Diseases, 66
-
Pawankar (2008)
State of the world allergy report 2008 -
A. Houwelingen, K. Kaczyńska, A. Kraneveld, Mirjam Kool, Frans Nijkamp, F. Redegeld (2007)
Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in miceClinical & Experimental Allergy, 37
-
R. Stoloff, R. Patterson, K. Harris, P. Greenberger (1993)
Idiopathic anaphylaxis.Allergy proceedings : the official journal of regional and state allergy societies, 14 2
-
Saito (2005)
Much atopy about the skin, 137
-
P. Avila (2007)
Does anti-IgE therapy help in asthma? Efficacy and controversies.Annual review of medicine, 58
-
K. Amin, D. Lúdvíksdóttir, C. Janson, O. Nettelbladt, E. Björnsson, G. Roomans, G. Boman, L. Sevéus, P. Venge (2000)
Inflammation and structural changes in the airways of patients with atopic and nonatopic asthma. BHR Group.American journal of respiratory and critical care medicine, 162 6
- Publisher
- Wiley
- Copyright
- © 2008 The Authors. Journal compilation © 2008 Blackwell Publishing Ltd
- ISSN
- 0954-7894
- eISSN
- 1365-2222
- DOI
- 10.1111/j.1365-2222.2008.03135.x
- pmid
- 19040467
- Publisher site
- See Article on Publisher Site
Abstract
Summary Allergic diseases have become a serious global health problem in the developed world. IgE interacting with its high‐affinitiy receptor FcɛRI is considered a major contributing factor to most types of allergies, but depending on the type of allergy, however, a subgroup of patients displays common symptoms and yet lack elevated levels of total serum IgE and/or antigen‐specific IgE. Novel therapeutic strategies such as anti‐IgE therapy may therefore not be applicable to these patients. It is clear, however, that these patients do display activation of mast cells. In several patients suffering from immunological disorders, an increase in free immunoglobulin (IG) light chain levels can be detected. Previously, we have described the capability of free light chains to elicit immediate hypersensitivity responses. In this Opinion article, we will discuss the role of IgE‐ and non‐IgE‐mediated mechanisms in allergic disorders and point out a possible role of free IG light chains in the pathogenesis of the non‐atopic types of these allergies.
Journal
Clinical & Experimental Allergy – Wiley
Published: Jan 1, 2009