Access the full text.
Sign up today, get DeepDyve free for 14 days.
(1992)
Effect of intracerebroventricular injection
E. Alvarez, A. Banzán (1986)
Histamine in dorsal and ventral hippocampus. II. Effects of H1 and H2 histamine antagonists on exploratory behavior in male ratsPhysiology & Behavior, 37
J. Glowinski, L. Iversen (1966)
REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐IJournal of Neurochemistry, 13
R. Cacabelos, X. Alvarez (1991)
Histidine decarboxylase inhibition induced by α-fluoromethylhistidine provokes learning-related hypokinetic activityAgents and Actions, 33
R. Oishi, M. Nishibori, Y. Itoh, K. Saeki, T. Fukuda, Y. Araki (2004)
Histamine turnover in the brain of morphine-dependent miceNaunyn-Schmiedeberg's Archives of Pharmacology, 337
D. Duggan, K. Hooke, A. Maycock (1984)
Inhibition of histamine synthesis in vitro and in vivo by S-α-fluoromethylhistidineBiochemical Pharmacology, 33
C. Kamei, Y. Chung, K. Tasaka (2005)
Influence of certain H1-blockers on the step-through active avoidance response in ratsPsychopharmacology, 102
(1983)
Effect of c~-ftuoromethylhistidine on the hista
E. Sakurai, H. Niwa, S. Yamasaki, K. Maeyama, T. Watanabe (1990)
The disposition of a histidine decarboxylase inhibitor (S)-alpha-fluoromethylhistidine in rats.The Journal of pharmacy and pharmacology, 42 12
(1978)
Aster SD (1978) Selective inhibitors
(1968)
Comprehensive observational assessment: Ia
M. Garbarg, G. Barbin, E. Rodergas, J. Schwartz (1980)
Inhibition of Histamine Synthesis in Brain by α‐Fluoromethylhistidine, a New Irreversible Inhibitor: In Vitro and In Vivo StudiesJournal of Neurochemistry, 35
(1990)
Effects of cholinergic drugs
C. Hall (1934)
Drive and emotionality: factors associated with adjustment in the rat.Journal of Comparative Psychology, 17
N. Sakai, Kenji Onodera, Kazutaka Maeyama, Kazuhiko Yanai, Takehiko Watanabe (1992)
Effects of (S)-alpha -fluoromethylhistidine and metoprine on locomotor activity and brain histamine content in mice.Life sciences, 51 6
C. Kamei, K. Tasaka (1993)
Effect of histamine on memory retrieval in old rats.Biological & pharmaceutical bulletin, 16 2
J. Groot (1959)
The rat forebrain in stereotaxic coordinates
D. Asdourian, John Dark, L. Chiodo, Paul Papich (1977)
Active avoidance in rats with unilateral hypothalamic and optic nerve lesionsPhysiology & Behavior, 19
J. Kollonitsch, J. Kollonitsch, A. Patchett, A. Patchett, S. Marburg, S. Marburg, A. Maycock, A. Maycock, L. Perkins, L. Perkins, G. Doldouras, G. Doldouras, D. Duggan, D. Duggan, S. Aster, S. Aster (1978)
Selective inhibitors of biosynthesis of aminergic neurotransmittersNature, 274
(1986)
Histamine in dorsal and ventral
C. Kamei, S. Tsujimoto, K. Tasaka (1990)
Effects of cholinergic drugs and cerebral metabolic activators on memory impairment in old rats.Journal of pharmacobio-dynamics, 13 12
R. Oishi, Miwa Baba, M. Nishibori, Y. Itoh, K. Saeki (2004)
Involvement of central histaminergic and cholinergic systems in the morphine-induced increase in blood-brain barrier permeability to sodium fluorescein in miceNaunyn-Schmiedeberg's Archives of Pharmacology, 339
C. Kamei, K. Tasaka (1991)
Participation of histamine in the step-through active avoidance response and its inhibition by H1-blockers.Japanese journal of pharmacology, 57 4
(1992)
Effect of intracerebroventricular injection of histamine on memory impairment induced by hippocampat lesions in rats
K. Maeyama, Takehiko Watanabe, A. Yamatodani, Y. Taguchi, Hiroshi Kambe, H. Wada (1983)
Effect of α‐Fluoromethylhistidine on the Histamine Content of the Brain of W/Wv Mice Devoid of Mast Cells: Turnover of Brain HistamineJournal of Neurochemistry, 41
(1991)
Studies with c~-fluoromethylhistidine as a probe
S. Irwin (1968)
Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mousePsychopharmacologia, 13
J. Glowinski, L. Iversen (1966)
Regional studies of catecholamines in the rat brain. 3. Subcellullar distribution of endogenous and exogenous catecholamines in various brain regions.Biochemical pharmacology, 15 7
Influence of certain H ~blockers on the step - through active avoidance response in rats
J. Papsdorf, M. Woodruff (1970)
Effects of bilateral hippocampectomy on the rabbit's acquisition of shuttle-box and passive-avoidance responses.Journal of comparative and physiological psychology, 73 3
(1970)
Effects of bilateral hippocamp
K. Tasaka, Y. Chung, K. Sawada, M. Mio (1989)
Excitatory effect of histamine on the arousal system and its inhibition by H1 blockers.Brain research bulletin, 22 2
S. Grossman (1970)
Avoidance behavior and aggression in rats with transections of the lateral connections of the medial or lateral hypothalamus.Physiology & behavior, 5 10
D. Duggan, K. Hooke, A. Maycock (1984)
Inhibition of histamine synthesis in vitro and in vivo by S-alpha-fluoromethylhistidine.Biochemical pharmacology, 33 24
J. McNew, R. Thompson (1966)
Role of the limbic system in active and passive avoidance conditioning in the rat.Journal of comparative and physiological psychology, 61 2
K. Onodera, A. Yamatodani, T. Watanabe (1992)
Effects of alpha-fluoromethylhistidine on locomotor activity, brain histamine and catecholamine contents in rats.Methods and findings in experimental and clinical pharmacology, 14 2
213 111 111 3 3 Chiaki Kamei Yasushi Okumura Kenji Tasaka Department of Pharmacology, Faculty of Pharmaceutical Sciences Okayama University 700 Okayama Japan Abstract To clarify the role of endogenous histamine in learning and memory, the effect of α-fluoromethylhistidine on active avoidance response in rats was studied. α-Fluoromethylhistidine (20–100 mg/kg or 10–50 µg) significantly ( P <0.05 or P <0.01) prolonged the response latency in active avoidance response when administered by either intraperitoneal or intracerebroventricular injection. These effects were dose-related and long lasting. A prolongation of the response latency induced by an intraperitoneal injection of α-fluoromethylhistidine (100 mg/kg) was antagonized by intracerebroventricular injection of histamine (10 and 20 ng) in a dose-dependent manner. In addition, the acquisition of this response was retarded by a consecutive intracerebroventricular injection of α-fluoromethylhistidine (50 µg), whereas histamine (100 ng) facilitated the response acquisition when administered by the same route. Both intraperitoneal (100 mg/kg) and intracerebroventricular injection of α-fluoromethylhistidine (50 µg) significantly ( P <0.05 or P <0.01) decreased the brain histamine content, especially in the hippocampus and hypothalamus. When α-fluoromethylhistidine (50 µg) was injected intracerebroventricularly, there is a high correlation between a prolongation of the response latency and a decrease in histamine content of these brain areas. Based on these findings, it was concluded that an intimate relation may exist between a prolongation of response latency in the active avoidance response and a decrease in the brain histamine content; endogenous histamine may play an important role in learning and memory recollection in rats.
Psychopharmacology – Springer Journals
Published: Jun 1, 1993
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.