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Urinary immunoreactive estrogen and pregnanediol‐3‐glucuronide during the normal menstrual cycle of the female lowland gorilla (Gorilla gorilla)American Journal of Primatology, 2
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Radioimmunoassay of pregnanediol concentrations in early morning urine specimens for assessment of luteal function in women.Fertility and sterility, 37 3
S. Shideler, N. Czekala, L. Kasman, D. Lindburg, B. Lasley (1983)
Monitoring ovulation and implantation in the lion-tailed macaque (Macaca silenus) through urinary estrone conjugate evaluations.Biology of reproduction, 29 4
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Paired urine and serum samples from four conceptive and six nonconceptive ovarian cycles of seven adult Macaca mullatta were analyzed by radioimmunoassay (RIA) for circulating estradiol (E2) and progesterone (Po), and urinary estrone conjugates (E1C) and immunoreactive preganediol‐3‐glucuronide (iPDG) using enzyme immunoassay (EIA). Nonconceptive cycles exhibited a fivefold increase in urinary E1C and serum E2 levels from follicular phase levels to the preovulatory peak. Linear correlation between urinary E1C and serum E2 nonconceptive cycle hormone levels was significant (P <0.01, r = 0.69). Luteal phase levels of iPDG and serum Po levels were approximately parallel in nonconceptive cycles. Similarly, conceptive cycle urinary E1C levels and serum E2 measurements had a correlation coefficient that was significant (P<0.01, r = 0.45). Nonconceptive and conceptive cycle iPDG and Po levels were significantly correlated (P = 0.05, r = 0.63, and P<0.01, r = 0.66, respectively). These data demonstrate that EIA measurements of ovarian hormones in daily urine samples can be used to accurately monitor ovarian function and early pregnancy in Macaca mulatta.
American Journal of Primatology – Wiley
Published: Jan 1, 1990
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