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resistance on total vascular in the forelimb of the dog A. JAMES LIEDTKE AND PHILLIP G. SCHMID Aerospace Medical Research Laboratories, Wright-Patterson Air Force Base, Ohio 45433 LIEDTKE, A. JAMES, AND PHILLIP G. SCHMID. Efect of vibration on total vascular resistance in the forelimb of the dog. J. A ppl. Physiol. 1969.-Whole-body, x-axis, mechanical vi26(l): 95-100. bration, defined in terms of frequency, peak acceleration, and displacement, was evaliuated in six dogs to determine its effect on the peripheral circulation and vascular smooth muscle. Changes in total vascular resistance in the canine forelimb, perfused at constant flow rate, were used to measure alterations in smooth muscle tone. One forelimb in each animal remained neurally intact; the other forelimb was denervated. Vibration for each animal was varied to include frequencies of 9, 12, and 16 cycles/set, at peak accelerations of 0.9, 1.2, and 1.6 g, and combined for a total of nine different runs. The order of assigning runs was randomized; each run lasted 1 min followed by 4-6 min recovery period. Vasodilation occurred in response to all levels of vibration in both the intact and denervated forelimbs. The magnitude of response varied inversely with frewith peak acceleration and displacement,
Journal of Applied Physiology – The American Physiological Society
Published: Jan 1, 1969
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