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Adult T-cell leukemia : antigen in an ATL cell line and detection of antibodies to the antigen in human sera -
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(1979)
Adult T-cell leukemia: Further clinical observation and cytogenetic and functional studies of leukemic cells
- Publisher
- Wiley
- Copyright
- © 1984 S. Karger AG, Basel
- ISSN
- 0042-9007
- eISSN
- 1423-0410
- DOI
- 10.1111/j.1423-0410.1984.tb00083.x
- Publisher site
- See Article on Publisher Site
Abstract
Possible transmission of adult T cell leukemia virus (ATLV) by blood transfusion was studied retrospectively. Of 41 recipients of whole blood or blood components containing cells from donors having antibodies to antigen that is associated with ATLV (anti‐ATLA), 26 (63.4%) produced anti‐ATLA. However, no anti‐ATLA was detected in all 14 recipients of fresh‐frozen plasma prepared from anti‐ATLA‐positive donors. None of 252 recipients of blood with cell components from anti‐ATLA‐negative donors produced anti‐ATLA. The development of anti‐ATLA in the recipients may correspond to antibody production after establishment of primary infection with ATLV that is associated with cells in blood from anti‐ATLA‐positive donors who are ATLV carriers.
Journal
Vox Sanguinis – Wiley
Published: May 1, 1984