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Journal of Alzheimerâs Disease 7 (2005) 235â239 IOS Press Special Report from the Challenging Views of Alzheimerâs Disease John C. Morrisa and Jeffrey Cummingsb Washington University School of Medicine, 4488 Forest Park Avenue, Suite 130, St. Louis, Missouri 6108, USA Tel.: +1 314 286 2881; Fax: +1 314 286 2763; E-mail: morrisj@abraxas.wustl.edu b David Geffen School of Medicine at UCLA, University of California Los Angeles, 710 Westwood Plaza, Ste 2-238, Los Angeles, CA 90095-1769, USA Tel.: +1 310 206 5238; Fax: +1 310 206 5287; E-mail: jcummings@mednet.ucla.edu 1. Introduction Although the conclusive diagnosis of Alzheimerâs disease rests on clinicopathological correlation, much now is known about its clinical and behavioral symptoms. The current clinical diagnostic process can identify AD with high accuracy (90% or higher in autopsyconï¬rmed series from dementia research centers) [3]. Clinical diagnostic tools include a careful history of the presentation and course of dementia and potentially contributing conditions (e.g., stroke, depression, medications), objective tests of cognitive function, physical and neurological examinations, and a limited number of laboratory procedures (thyroid function tests, vitamin B12 levels, and neuroimaging). Standard diagnostic criteria and assessment procedures for AD have been published in a Practice Parameter by the American Academy of
Journal of Alzheimer's Disease – IOS Press
Published: Jan 1, 2005
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