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PARVOVIRUS B19 IN HUMAN DISEASE 1

PARVOVIRUS B19 IN HUMAN DISEASE 1 ▪ Abstract Parvovirus B19, the only known human pathogenic parvovirus, is associated with a wide range of disease manifestations. In healthy individuals, the major presentation of B19 infection is erythema infectiosum. In patients with underlying hemolytic disorders, infection is the primary cause of transient aplastic crisis. In immunosuppressed patients, persistent infection may develop that presents as pure red cell aplasia and chronic anemia. In utero infection may result in hydrops fetalis or congenital anemia. Diagnosis is based on examination of bone marrow and virologic studies. Much is known of the pathophysiology of the virus, and studies are in progress to develop a vaccine to prevent this widespread infection. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Medicine Annual Reviews

PARVOVIRUS B19 IN HUMAN DISEASE 1

Brown, MD, K.E.; Young, MD, N.S.
Annual Review of Medicine , Volume 48 (1) – Feb 1, 1997
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Publisher
Annual Reviews
Copyright
Copyright 1997 Annual Reviews. All rights reserved
Subject
Review Articles
ISSN
0066-4219
eISSN
1545-326X
DOI
10.1146/annurev.med.48.1.59
pmid
9046945
Publisher site
See Article on Publisher Site

Abstract

▪ Abstract Parvovirus B19, the only known human pathogenic parvovirus, is associated with a wide range of disease manifestations. In healthy individuals, the major presentation of B19 infection is erythema infectiosum. In patients with underlying hemolytic disorders, infection is the primary cause of transient aplastic crisis. In immunosuppressed patients, persistent infection may develop that presents as pure red cell aplasia and chronic anemia. In utero infection may result in hydrops fetalis or congenital anemia. Diagnosis is based on examination of bone marrow and virologic studies. Much is known of the pathophysiology of the virus, and studies are in progress to develop a vaccine to prevent this widespread infection.

Journal

Annual Review of Medicine – Annual Reviews

Published: Feb 1, 1997

There are no references for this article.