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TOBACCO MOSAIC VIRUS: A Model System for Plant Biology

TOBACCO MOSAIC VIRUS: A Model System for Plant Biology ▪ Abstract Tobacco mosaic virus (TMV) has had an illustrious history for more than 100 years, dating to Beijerinck's description of the mosaic disease of tobacco as a contagium vivum fluidum and the modern usage of the word “virus.” Since then, TMV has been acknowledged as a preferred didactic model and a symbolic model to illuminate the essential features that define a virus. TMV additionally emerged as a prototypic model to investigate the biology of host plants, namely tobacco. TMV also exemplifies how a model system furthers novel, and often unexpected, developments in biology and virology. Today, TMV is used as a tool to study host-pathogen interactions and cellular trafficking, and as a technology to express valuable pharmaceutical proteins in tobacco. The history of TMV illustrates how pragmatic strategies to control an economically important disease of tobacco have had unexpected and transforming effects across platforms that impinge on plant health and public health. Tobacco mosaic virus: An RNA virus that causes mosaic disease in tobacco and similar effects in other plants, much used as an experimental subject; abbrev. TMV . (8) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annual Review of Phytopathology Annual Reviews

TOBACCO MOSAIC VIRUS: A Model System for Plant Biology

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Publisher
Annual Reviews
Copyright
Copyright © 2004 by Annual Reviews. All rights reserved
ISSN
0066-4286
eISSN
1545-2107
DOI
10.1146/annurev.phyto.42.040803.140322
pmid
15283658
Publisher site
See Article on Publisher Site

Abstract

▪ Abstract Tobacco mosaic virus (TMV) has had an illustrious history for more than 100 years, dating to Beijerinck's description of the mosaic disease of tobacco as a contagium vivum fluidum and the modern usage of the word “virus.” Since then, TMV has been acknowledged as a preferred didactic model and a symbolic model to illuminate the essential features that define a virus. TMV additionally emerged as a prototypic model to investigate the biology of host plants, namely tobacco. TMV also exemplifies how a model system furthers novel, and often unexpected, developments in biology and virology. Today, TMV is used as a tool to study host-pathogen interactions and cellular trafficking, and as a technology to express valuable pharmaceutical proteins in tobacco. The history of TMV illustrates how pragmatic strategies to control an economically important disease of tobacco have had unexpected and transforming effects across platforms that impinge on plant health and public health. Tobacco mosaic virus: An RNA virus that causes mosaic disease in tobacco and similar effects in other plants, much used as an experimental subject; abbrev. TMV . (8)

Journal

Annual Review of PhytopathologyAnnual Reviews

Published: Sep 8, 2004

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