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(1977)
Catecholamine-induced release
T. Reisine, H. Wang, S. Guild (1988)
Somatostatin inhibits cAMP-dependent and cAMP-independent calcium influx in the clonal pituitary tumor cell line AtT-20 through the same receptor population.The Journal of pharmacology and experimental therapeutics, 245 1
P. Adams, D. Brown (1980)
LUTEINIZING HORMONE‐RELEASING FACTOR AND MUSCARINIC AGONISTS ACT ON THE SAME VOLTAGE‐SENSITIVE K+ ‐CURRENT IN BULLFROG SYMPATHETIC NEURONESBritish Journal of Pharmacology, 68
A. Brown, L. Birnbaumer (1988)
Direct G protein gating of ion channels.The American journal of physiology, 254 3 Pt 2
S. Jones (1985)
Muscarinic and peptidergic excitation of bull‐frog sympathetic neurones.The Journal of Physiology, 366
(1987)
Probable role of a GTP-binding protein in mediating M-current inhibition by muscarine in rat sympathetic neurones
(1986)
Effects of phorbol ester on slow potassium currents of Bullfrog ganglion cells
R. Purves (1976)
Function of muscarinic and nicotinic acetylcholine receptorsNature, 261
(1985)
Modulation of potassium currents of vertebrate neurons
G. Holz, S. Rane, K. Dunlap (1986)
GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channelsNature, 319
K. Jakobs (1983)
Determination of the turn-off reaction for the epinephrine-inhibited human platelet adenylate cyclase.European journal of biochemistry, 132 1
Kenji Kuba, Kyozo Koketsu (1976)
Analysis of the slow excitatory postsynaptic potential in bullfrog sympathetic ganglion cells.The Japanese journal of physiology, 26 6
Stephen, Fisher, P. Klinger, Bernard, Agranoff (1983)
Muscarinic agonist binding and phospholipid turnover in brain.The Journal of biological chemistry, 258 12
(1978)
Bullfrog sympathetic ganglion cells
A. Finkel, S. Redman (1984)
Theory and operation of a single microelectrode voltage clampJournal of Neuroscience Methods, 11
(1980)
Luteinizing hormone - releasing factor and muscarinic agonists act on the same voltage - sensitive K + - current in Bullfrog sympathetic neurons
Katada Katada, Ui Ui (1982)
Direct modification of the membrane adenylate cyclase system by islet‐activating protein due to ADP‐ribosylationProc. Natl. Acad. Sci. USA, 79
M. Ui (1984)
Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclaseTrends in Pharmacological Sciences, 5
P. Adams, David Brown, A. Constanti (1982)
M‐currents and other potassium currents in bullfrog sympathetic neuronesThe Journal of Physiology, 330
(1980)
Luteinizing hormone-releasing factor
Carlos Oliva, I Cohen, Richard Mathias (1988)
Calculation of time constants for intracellular diffusion in whole cell patch clamp configuration.Biophysical journal, 54 5
By Blackman, L. B., GINSBORGt (1963)
Synaptic transmission in the sympathetic ganglion of the frogThe Journal of Physiology, 167
D. Cassel, Z. Selinger (1977)
Catecholamine-induced release of [3H]-Gpp(NH)p from turkey erythrocyte adenylate cyclase.Journal of cyclic nucleotide research, 3 1
(1988)
Mechanism of muscarinic receptorinduced K+ channel activation as revealed by hydrolysis-resistant GTP analogs
G. Breitwieser, G. Szabó (1985)
Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogueNature, 317
T. Jacquin, Jean Champagnat, S. Madamba, M. Denavit‐Saubié, G. Siggins (1988)
Somatostatin depresses excitability in neurons of the solitary tract complex through hyperpolarization and augmentation of IM, a non-inactivating voltage-dependent outward current blocked by muscarinic agonists.Proceedings of the National Academy of Sciences of the United States of America, 85 3
F. Eckstein, D. Cassel, H. Levkovitz, M. Lowe, Z. Selinger (1979)
Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.The Journal of biological chemistry, 254 19
T. Katada, M. Ui (1981)
Islet-activating protein. A modifier of receptor-mediated regulation of rat islet adenylate cyclase.The Journal of biological chemistry, 256 16
Hamill Hamill, Marty Marty, Neher Neher, Sakmann Sakmann, Sigworth Sigworth (1981)
Improved patch‐clamp techniques for high‐resolution current recording from cells and cell‐free membrane patchesPflugers Arch., 391
L. Eiden, R. Eskay (1980)
Characterization of LRF-like immunoreactivity in the frog sympathetic ganglia: Non-identity with LRF decapeptideNeuropeptides, 1
D. Cassel, F. Eckstein, M. Lowe, Z. Selinger (1979)
Determination of the turn-off reaction for the hormone-activated adenylate cyclase.The Journal of biological chemistry, 254 19
K. Kuba, K. Koketsu (1978)
Synaptic events in sympathetic gangliaProgress in Neurobiology, 11
(1982)
Two chemically and immunologically distinct forms of luteinizing hormone-313-317
T. Akasu, K. Hirai, K. Koketsu (1983)
Modulatory actions of ATP on membrane potentials of bullfrog sympathetic ganglion cellsBrain Research, 258
Gerda Breitwieser, Gabor Szabo (1988)
Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analoguesThe Journal of General Physiology, 91
J. Fain, M. Wallace, R. Wojcikiewicz (1988)
Evidence for involvement of guanine nucleotide‐binding regulatory proteins in the activation of phospholipases by hormonesThe FASEB Journal, 2
Eckstein Eckstein, Cassel Cassel, Levkovitz Levkovitz, Lowe Lowe, Selinger Selinger (1979)
Guanosine 5′‐O‐(2‐Thiodiphosphate)An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions. J. Biol. Chem., 254
P. Pfaffinger, M. Leibowitz, E. Subers, N. Nathanson, W. Almers, B. Hille (1988)
Agonists that suppress M-current elicit phosphoinositide turnover and Ca2+ transients, but these events do not explain M-current suppressionNeuron, 1
(1987)
GTP-g-S inhibits the M-current of dissociated Bullfrog sympathetic neurons
P. Adams, D. Brown, A. Constanti (1982)
Pharmacological inhibition of the M‐currentThe Journal of Physiology, 332
A. Constanti, P. Adams, David Brown (1981)
Why do barium ions imitate acetylcholine?Brain Research, 206
T. Akasu, J. Gallagher, K. Koketsu, P. Shinnick‐Gallagher (1984)
Slow excitatory post‐synaptic currents in bull‐frog sympathetic neurones.The Journal of Physiology, 351
K. Dunlap, G. Holz, S. Rane (1987)
G proteins as regulators of ion channel functionTrends in Neurosciences, 10
L. Eiden, E. Loumaye, N. Sherwood, R. Eskay (1982)
Two chemically and immunologically distinct forms of luteinizing hormone-releasing hormone are differentially expressed in frog neural tissuesPeptides, 3
P. Pfaffinger (1988)
Muscarine and t-LHRH suppress M-current by activating an IAP- insensitive G-protein, 8
H. Higashida, D. Brown (1986)
Two polyphosphatidylinositide metabolites control two K+ currents in a neuronal cellNature, 323
Atsuko Yatani, Juan Codina, Ronald Sekura, L. Birnbaumer, A. Brown (1987)
Reconstitution of somatostatin and muscarinic receptor mediated stimulation of K+ channels by isolated GK protein in clonal rat anterior pituitary cell membranes.Molecular endocrinology, 1 4
(1984)
The role of protein kinase C in cell surface signal transduction and turnover promotion
(1987)
Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca*+-dependent
Y. Jan, L. Jan, S. Kuffler
A peptide as a possible transmitter in sympathetic ganglia of the frog
Y. Nishizuka (1984)
The role of protein kinase C in cell surface signal transduction and tumour promotionNature, 308
P. Dutar, R. Nicoll (1988)
Stimulation of phosphatidylinositol (PI) turnover may mediate the muscarinic suppression of the M-current in hippocampal pyramidal cellsNeuroscience Letters, 85
G. Aghajanian, Yanyan Wang (1987)
Common α2- and opiate effector mechanisms in the locus coeruleus: intracellular studies in brain slicesNeuropharmacology, 26
Y. Jan, L. Jan, S. Kuffler (1980)
Further evidence for peptidergic transmission in sympathetic ganglia.Proceedings of the National Academy of Sciences of the United States of America, 77 8
K. Sasaki, Makoto Sato (1987)
A single GTP-binding protein regulates K+-channels coupled with dopamine, histamine and acetylcholine receptorsNature, 325
(1988)
Somatostatin depresses excitability in neurons
J. Codina, A. Yatani, D. Grenet, A. Brown, L. Birnbaumer (1987)
The alpha subunit of the GTP binding protein Gk opens atrial potassium channels.Science, 236 4800
S. Moore, S. Madamba, M. Joëls, G. Siggins (1988)
Somatostatin augments the M-current in hippocampal neurons.Science, 239 4837
Andrew Morris, D. Gallacher, R. Irvine, Ole Petersen (1987)
Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channelsNature, 330
H. Hartzell (1981)
Mechanisms of slow postsynaptic potentialsNature, 291
S. Kuffler (1980)
Slow synaptic responses in autonomic ganglia and the pursuit of a peptidergic transmitter.The Journal of experimental biology, 89
Inositol lipids and signal transduction at CNS muscarinic receptors. TIPS
P. Sternweis, J. Robishaw (1984)
Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.The Journal of biological chemistry, 259 22
M. Vallejo, Trevor Jackson, S. Lightman, M. Hanley (1987)
Occurrence and extracellular actions of inositol pentakis- and hexakisphosphate in mammalian brainNature, 330
P. Adams, D. Brown, S. Jones (1983)
Substance P inhibits the M‐current in bullfrog sympathetic neuronesBritish Journal of Pharmacology, 79
P. Adams, S. Jones, P. Pennefather, D. Brown, C. Koch, B. Lancaster (1986)
Slow synaptic transmission in frog sympathetic ganglia.The Journal of experimental biology, 124
M. Lochrie, Melvin Simon (1988)
G protein multiplicity in eukaryotic signal transduction systems.Biochemistry, 27 14
J. Lemos, I. Levitan (1984)
Intracellular injection of guanyl nucleotides alters the serotonin- induced increase in potassium conductance in Aplysia neuron R15The Journal of General Physiology, 83
M. Schramm, M. Rodbell (1975)
A persistent active state of the adenylate cyclase system produced by the combined actions of isoproterenol and guanylyl imidodiphosphate in frog erythrocyte membranes.The Journal of biological chemistry, 250 6
P. Pfaffinger, Jennifer Martin, D. Hunter, N. Nathanson, B. Hille (1985)
GTP-binding proteins couple cardiac muscarinic receptors to a K channelNature, 317
N. Sherwood, L. Eiden, M. Brownstein, J. Spiess, J. Rivier, W. Vale (1983)
Characterization of a teleost gonadotropin-releasing hormone.Proceedings of the National Academy of Sciences of the United States of America, 80 9
P. Worley, J. Baraban, M. McCarren, S. Snyder, B. Alger (1987)
Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked neurotransmitter actions: electrophysiological studies in rat hippocampus.Proceedings of the National Academy of Sciences of the United States of America, 84 10
T. Katada, And, Ui Michio (1982)
Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.Proceedings of the National Academy of Sciences of the United States of America, 79 10
L. Jan, Y. Jan (1982)
Peptidergic transmission in sympathetic ganglia of the frog.The Journal of Physiology, 327
(1986)
Inositol lipids and signal transduction at CNS muscarinic receptors
Katada Katada, Bokoch Bokoch, Smigel Smigel, Ui Ui, Gilman Gilman (1984)
The inhibitory guanine nucleotide‐binding regulatory component of adenylate cyclaseJ. Biol. Chem., 259
(1975)
Activation of adenylate
(1986)
Inositol lipids and signal transduction at CNS muscarinic receptors . TIPS , Feb
S. Kuffler, T. Sejnowski (1983)
Peptidergic and muscarinic excitation at amphibian sympathetic synapses.The Journal of Physiology, 341
R. Nicoll (1988)
The coupling of neurotransmitter receptors to ion channels in the brain.Science, 241 4865
C. Downes (1988)
Inositol phosphates: a family of signal molecules?Trends in Neurosciences, 11
M. Graziano, A. Gilman (1987)
Guanine nucleotide-binding regulatory proteins; mediators of transmembrane signalingTrends in Pharmacological Sciences, 8
A. Dolphin, R. Scott (1987)
Calcium channel currents and their inhibition by (‐)‐baclofen in rat sensory neurones: modulation by guanine nucleotides.The Journal of Physiology, 386
(1981)
Why do barium ions
J. Horwitz, S. Tsymbalov, R. Perlman (1984)
Muscarine increases tyrosine 3-monooxygenase activity and phospholipid metabolism in the superior cervical ganglion of the rat.The Journal of pharmacology and experimental therapeutics, 229 2
Brown Brown, Adams Adams (1987)
Effects of phorbol dibutyrate on M currents and M current inhibition in Bullfrog sympathetic neuronsCell. Mol. Neurobiol., 7
(1982)
M-currents and other
P. Cuatrecasas, S. Jacobs, V. Bennett (1975)
Activation of adenylate cyclase by phosphoramidate and phosphonate analogs of GTP: possible role of covalent enzyme-substrate intermediates in the mechanism of hormonal activation.Proceedings of the National Academy of Sciences of the United States of America, 72 5
(1985)
Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels
Y. Momose, W. Giles, G. Szabó (1984)
Acetylcholine-induced k current in amphibian atrial cells.Biophysical journal, 45 1
(1987)
Possible involvement of GTP - binding proteins in coupling of muscarinic receptors to M - current in Bullfrog ganglion cells
Kurachi Kurachi, Nakajima Nakajima, Sugimoto Sugimoto (1986)
On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP‐binding proteinPflugers Arch., 407
P. Adams, D. Brown (1982)
Synaptic inhibition of the M‐current: slow excitatory post‐synaptic potential mechanism in bullfrog sympathetic neurones.The Journal of Physiology, 332
(1982)
inhibited human platelet adenylate cyclase
R. Andrade, R. Malenka, R. Nicoll (1986)
A G protein couples serotonin and GABAB receptors to the same channels in hippocampus.Science, 234 4781
(1986)
Inositide metabolism in the brain: its potential role in complex neuronal pathways
(1985)
Overview of the guanine nucleotide regulatory protein systems, N, and N,, which regulate adenylate cyclase activity in plasma membranes
G. Milligan (1988)
Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins.The Biochemical journal, 255 1
S. Jones, P. Adams, M. Brownstein, J. Rivier (1984)
Teleost luteinizing hormone-releasing hormone: action on bullfrog sympathetic ganglia is consistent with role as neurotransmitter, 4
Y. Katayama, S. Nishi (1982)
Voltage‐clamp analysis of peptidergic slow depolarizations in bullfrog sympathetic ganglion cells.The Journal of Physiology, 333
K. Ferguson, T. Higashijima, M. Smigel, A Gilman (1986)
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.The Journal of biological chemistry, 261 16
(1985)
Muscarinic and peptidergic excitation of Bullfrog
A. Gilman (1987)
G proteins: transducers of receptor-generated signals.Annual review of biochemistry, 56
Gary BokochSQ, T. Katadas, John, NorthupSY, Michio Uill, Alfred Gilmans (1984)
Purification and properties of the inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase.The Journal of biological chemistry, 259 6
The involvement of G proteins in the transduction mechanism of M current (Im) inhibition by extracellular ligands in bullfrog sympathetic neurons was examined using the hydrolysis resistant nucleotide analogues GTPγS and GDPβS. Im was recorded in large (40–60 μm) isolated neurons using the patch‐clamp technique in the whole‐cell configuration, as well as in neurons from the intact ganglion impaled with conventional microelectrodes. In whole‐cell recordings Im could be recorded without significant loss for 1 h or more provided ATP was present in the patch pipette. Muscarine, D‐Ala6‐LHRH, substance P and UTP reversibly inhibited Im in isolated control neurons, with full and rapid recovery of the current following agonist washout. Dialysis of isolated neurons with various concentrations of GTPγS (1–100 μM) affected, in a dose‐dependent manner, the recovery of Im after its inhibition by brief agonist application. With 50 μM GTPμS, Im inhibition became completely irreversible. Similarly, the reversibility of Im inhibition by muscarine was reduced or abolished by the iontophoretic injection of GTPμS through a second microelectrode into neurons of the intact ganglion. GTPμS by itself caused a slow, agonist‐independent suppression of Im in dialysed neurons, thus mimicking agonist action. Dialysis of isolated neurons with GDPβS (100—500 μM) attenuated by half or more the magnitude of Im inhibition by agonist as compared to control neurons. In addition, GDPβS attenuated the response of a given neuron to muscarine and D‐Ala6‐LHRH, and caused slow increase of Im, as a function of dialysis time. Incubation (2–72 h, 4–36°C) of isolated neurons or intact ganglions with activated pertussis toxin had no effect on the response to muscarine. Toxin injections to experimental animals were equally ineffective. In contrast to Im, the additional inward current with increase in conductance induced by muscarine and D‐Ala6‐LHRH reversed with agonist washout in GTPγS‐dialysed neurons, although more slowly than in control neurons. The results in this study indicate that a G protein, possibly pertussis toxin‐insensitive, provides a common coupling step linking muscarinic, substance P, D‐Ala6‐LHRH and UTP receptors to the inhibition of M current.
European Journal of Neuroscience – Wiley
Published: Sep 1, 1989
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