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Moore Moore, Johnson Johnson, Traver Traver, Garner Garner, Coffman Coffman, Amend Amend, Tritschler Tritschler (1977)
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SUMMARY Caecal fluid samples collected 8 and 24 hours after carbohydrate overload were quantitatively compared to control samples in terms of aerobic and anaerobic bacteria. Concomitant increases in lactic acid‐producing bacteria and decreases in Gram negative bacteria were substantiated during the onset of acute laminitis. Progressive decreases in caecal fluid pH were also quantitated. Although endotoxin assays of caecal fluid and blood were not done, the caecal flora changes suggest its presence during the onset of acute laminitis. RÉSUMÉ Des échantillons de fluide coecal recueillis 8 et 24 heures apràs une surcharge digestive en hydrates de carbone furent comparés à des échantillons témoins pour apprécier les modifications de la flore aérobie et anaérobie. On constata une augmentation des bactéries productrices d'acide lactique et une diminution des bactéries Gram—avec installation des signes de fourbure aigue. Une diminution progressive du Ph du liquide coecal fut également remarquée. On ne contrôla point la présence d'antoxines dans le liquide coecal ni dans le sang. Mais les variations de la flore coecale laissent penser à l'existence de telles toxines au début de la fourbure aigue. ZUSAMMENFASSUNG Blinddarminhalt wurde 8 und 24 Stunden nach Kohlenhydratüberfütterung entnommen und quantitativ verglichen mit Kontrollproben (Zahl der aeroben und anaeroben Bakterien). Beim Eintritt einer akuten Hufrehe kommt es gleichzeitig zu einer Vermehrung von Lactat‐produzierenden Bakterien und zu einer Verminderung von Gram‐negativen Keimen. Ein zunehmender Abfall des pH im Blindarminhalt konnte ebenfalls quantitativ erhärtet werden. Obgleich Endotoxinbestimmungen in der Blinddarmflüssigkeit und im Blut nicht vorgenommen werden konnten, kann das Vorhandensein von Endotoxin aufgrund der Veränderungen der Flora beim Eintritt einer akuten Rehe vermutet werden.
Equine Veterinary Journal – Wiley
Published: Oct 1, 1978
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